CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes. [PDF]
Ding M +12 more
europepmc +1 more source
Summary Background Plasma L‐lactate (lactate) is widely used as a prognostic marker in horses with acute gastrointestinal disease (colic), but association with obesity is unclear. In humans, plasma lactate is correlated with obesity and insulin resistance. Objectives This study aims to evaluate the association of obesity (body condition score ≥7/9) and
A. L. Tillisch +4 more
wiley +1 more source
SENP2 regulates UCP1-dependent thermogenesis in brown adipocytes via deSUMOylation of ERRα. [PDF]
Choe HJ +6 more
europepmc +1 more source
A Novel LncRNA MSTRG.310246.1 Promotes Differentiation and Thermogenesis in Goat Brown Adipocytes. [PDF]
Tang J +10 more
europepmc +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source
Deletion of PPARα in mouse brown adipocytes increases their De Novo Lipogenesis. [PDF]
Batrow PL +15 more
europepmc +1 more source
A purinergic call to arms from dying brown adipocytes. [PDF]
Hankir MK.
europepmc +1 more source
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira +8 more
wiley +1 more source
Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice. [PDF]
Wu H +6 more
europepmc +1 more source
Specific and efficient gene knockout and overexpression in mouse interscapular brown adipocytes in vivo. [PDF]
Xue K, Wu D, Qiu Y.
europepmc +1 more source

