Results 191 to 200 of about 39,242 (266)

The Role of miR-326-3p in Regulating Differentiation and Thermogenesis Genes in Goat Brown Adipocytes. [PDF]

Genes (Basel)
Zhu Y, Suo L, Jiang T, Jiang X, Xia Y, Wang L.   +5 more
europepmc   +1 more source

Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes. [PDF]

iScience, 2023
Kwon J, Yeh YS, Kawarasaki S, Minamino H, Fujita Y, Okamatsu-Ogura Y, Takahashi H, Nomura W, Matsumura S, Yu R, Kimura K, Saito M, Inagaki N, Inoue K, Kawada T, Goto T.   +15 more
europepmc   +1 more source

Human Islet miR‐199a‐5p and miR‐214‐3p Associate With Donor Age, BMI, and Sex and Mediate Cellular Aging in Islet‐Derived Cells

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Objectives Human islets are widely researched to understand pathophysiological mechanisms leading to diabetes. Sex, age, and body mass index (BMI) are key donor traits influencing islet function, which is also regulated by an intricate network of microRNAs.
Wilson K. M. Wong, Isabelle El‐Azzi, Aditya Nachanekar, Ehsan Alvandi, Nhan Ho Trong Pham, Hrishikesh P. Hardikar, Mya Polkamp, Vijit Saini, Feifei Cheng, Guozhi Jiang, Anja E. Sørensen, Yi Vee Chew, Helen E. Thomas, Thomas Loudovaris, Ronald C. W. Ma, Wayne J. Hawthorne, Louise T. Dalgaard, Mugdha V. Joglekar, Anandwardhan A. Hardikar   +18 more
wiley   +1 more source

Ei24 deficiency in brown adipocytes induces severe hypothermia under cold stress independent of UCP1 activity. [PDF]

Nat Commun
Lee SB, Thanh Thu B, Nam TW, Song Y, Lee JH, Jeong Y, Lee HW.   +6 more
europepmc   +1 more source

A CRISPR Screen Identifies the E3 Ubiquitin Ligase Rfwd2 as a Negative Regulator of Glucose Uptake in Brown Adipocytes. [PDF]

Genes (Basel), 2023
Lynes MD, Huang Q, Cora C, Su SC, Yi P, Tseng YH.   +5 more
europepmc   +1 more source

Jiuwei Xiaozhi Decoction Alleviates High‐Fat Diet‐Induced MASLD by Suppressing Hepatic SREBP2‐Driven Cholesterogenesis and Restoring PPARα‐Mediated Fatty Acid Oxidation

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Studies have found that Jiuwei Xiaozhi Decoction can improve high‐fat diet‐induced fatty liver disease, mainly by regulating the SREBP2 and PPARα pathways to balance hepatic lipid metabolism while reducing inflammatory responses. ABSTRACT Jiuwei Xiaozhi Decoction (JWXZ) is a nine‐herb traditional Chinese medicine formula clinically used for hepatic ...
Youcheng Ma, Xinrui Gao, Ji Wang, Lingru Li, Zhen Huang, Fangli Li   +5 more
wiley   +1 more source

Cold Exposure Induces Swine Brown Adipocytes to Display an Island-like Distribution with Atypical Characteristics. [PDF]

Int J Mol Sci
Guo Z, Lv L, Ma H, Wang L, Fu B, Wang F, Yang S, Liu D, Zhang D.   +8 more
europepmc   +1 more source

ACOX-driven peroxisomal heterogeneity and functional compartmentalization in brown adipocytes of hypothyroid rats. [PDF]

R Soc Open Sci, 2023
Aleksic M, Golic I, Jankovic A, Cvoro A, Korac A.   +4 more
europepmc   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Targeted Disruption of Selenocysteine Lyase in Brown Adipocytes Controls Glutathione Peroxidase 1 and 4 Expression in Males. [PDF]

Biol Trace Elem Res
Santiago PJD, Shimada BK, Alfulaij N, Hallam KA, Soares AG, Young V, Swanson SM, Remedios GL, Toh P, Seale LA.   +9 more
europepmc   +1 more source