Results 161 to 170 of about 186,568 (350)
Two-step regulation by matrix Gla protein in brown adipose cell differentiation
Molecular MetabolismObjective: Bone morphogenetic protein (BMP) signaling is intricately involved in adipose tissue development. BMP7 together with BMP4 have been implicated in brown adipocyte differentiation but their roles during development remains poorly specified ...
Li Zhang +10 more
doaj +1 more source
Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis. [PDF]
, 2019 Thermogenesis in brown adipose tissue (BAT) declines with age; however, what regulates this process remains poorly understood. Here, we identify mitochondria lipoylation as a previously unappreciated molecular hallmark of aged BAT in mice.
Chang, Chih-Hsiang +9 more
core
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
mmunohistochemical Identification And Quantification Of Brown Adipocytes In Human Adipose Tissue.
مجله كليه طب الكندي, 2016 Background: Obesity is a worldwide challenge and is closely connected to many metabolic diseases. Two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT) have been identified.
Insaf Jasim Mahmoud +3 more
doaj
Food Bioengineering, EarlyView.Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi +4 more
wiley +1 more source
Aloe vera Tannin Ameliorates Fructose‐Induced Dyslipidaemia and Oxidative Stress in Wistar Rats
Food Chemistry International, EarlyView.Aloe vera tannin (AVT) significantly enhances liver reduced glutathione and superoxide dismutase activities in rats. Fructose consumption creates dyslipidaemia in rats by significantly increasing serum cholesterol and LDL levels. AVT prevented fructose‐induced dyslipidaemia in rats by controlling the lipid profile. AVT did not affect liver, hippocampus
Nathan Isaac Dibal +12 more
wiley +1 more source
Food Frontiers, EarlyView.This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu +12 more
wiley +1 more source
Knockdown of VEGFB/VEGFR1 Signaling Promotes White Adipose Tissue Browning and Skeletal Muscle Development [PDF]
, 2022 Mingfa Ling +14 more
openalex +1 more source