Results 11 to 20 of about 1,390,341 (404)
Assessment of brown adipose tissue function [PDF]
Frontiers in Physiology, 2013 In this review we discuss practical considerations for the assessment of brown adipose tissue in rodent models, focusing on mice. The central aim of the review is to provide a critical appraisal of the utility of specialised techniques for assessing ...
Samuel eVirtue +2 more
doaj +4 more sources
Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S] [PDF]
Journal of Lipid Research, 2018 In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade
P. Kotzbeck +11 more
semanticscholar +5 more sources
Current Opinion in Clinical Nutrition and Metabolic Care, 2012 Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure,
Townsend, Kristy L, Tseng, Yu-Hua
core +4 more sources
Brown and Beige Adipose Tissue and Aging [PDF]
Frontiers in Endocrinology, 2019 Across aging, adipose tissue (AT) changes its quantity and distribution: AT becomes dysfunctional with an increase in production of inflammatory peptides, a decline of those with anti-inflammatory activity and infiltration of macrophages.
E. Zoico +7 more
semanticscholar +6 more sources
Brown Adipose Tissue Growth and Development [PDF]
Scientifica, 2013 Brown adipose tissue is uniquely able to rapidly produce large amounts of heat through activation of uncoupling protein (UCP) 1. Maximally stimulated brown fat can produce 300 watts/kg of heat compared to 1 watt/kg in all other tissues.
Michael E. Symonds
doaj +3 more sources
Renaissance of Brown Adipose Tissue [PDF]
Hormone Research in Paediatrics, 2011 The recent discovery of functional brown adipose tissue in human adults raised this tissue again into the focus of current investigations concerning human energy homeostasis. Brown fat is a key thermogenic tissue and is essential for non-shivering thermogenesis in the human newborn and hibernating mammals.
Tews, D., Wabitsch, M.
openaire +3 more sources
Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning
International Journal of Molecular Sciences, 2022 The present narrative review gathers the studies reported so far, addressing sex differences in the effects of cold exposure, feeding pattern and age on brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning. In rodents, when exposed to decreasing temperatures, females activate thermogenesis earlier. Results obtained in humans
Iker Gómez-García +4 more
openaire +5 more sources
Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
Frontiers in Endocrinology, 2020 Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann +14 more
doaj +1 more source
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
doaj +1 more source
iScience, 2023 Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulation of
Moisés Castellá +18 more
doaj +1 more source