Results 41 to 50 of about 186,568 (350)

Polyunsaturated fatty acids stimulate de novo lipogenesis and improve glucose homeostasis during refeeding with high fat diet [PDF]

, 2017
The recovery of body weight after a period of caloric restriction is accompanied by an enhanced efficiency of fat deposition and hyperinsulinemia—which are exacerbated by isocaloric refeeding on a high fat diet rich in saturated and monounsaturated ...
Bianco, Francesca, Cancelliere, Rosa, Crescenzo, Raffaella, Dulloo, Abdul G., Giacco, Antonia, Iossa, Susanna, Liverini, Giovanna, Mazzoli, Arianna   +7 more
core   +1 more source

Brown adipose tissue and bone [PDF]

International Journal of Obesity Supplements, 2015
Brown adipose tissue (BAT) is capable of transforming chemically stored energy, in the form of triglycerides, into heat. Recent studies have shown that metabolically active BAT is present in a large proportion of adult humans, where its activity correlates with a favorable metabolic status. Hence, the tissue is now regarded as an interesting target for
M E, Lidell, S, Enerbäck
openaire   +2 more sources

Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency

EBioMedicine, 2019
Background: Inflammation is the most relevant mechanism linking obesity with insulin-resistance and metabolic disease. It impacts the structure and function of tissues and organs involved in metabolism, such as the liver, pancreatic islets and the ...
José C. de-Lima-Júnior, Gabriela F. Souza, Alexandre Moura-Assis, Rodrigo S. Gaspar, Joana M. Gaspar, Andréa L. Rocha, Danilo L. Ferrucci, Tanes I. Lima, Sheila C. Victório, Ivan L.P. Bonfante, Claudia R. Cavaglieri, José C. Pareja, Sérgio Q. Brunetto, Celso D. Ramos, Bruno Geloneze, Marcelo A. Mori, Leonardo R. Silveira, Gesmar R.S. Segundo, Eduardo R. Ropelle, Lício A. Velloso   +19 more
doaj   +1 more source

The effect of estrogen on brown adipose tissue activity in male rats

BMC Research Notes, 2022
Objective Centrally administered estrogen can increase sympathetic nerve activity to brown adipose tissue, resulting in thermogenesis. The central thermogenic effects of estrogen have not been investigated in males.
W. Sievers, C. Kettle, R. A. Green, L. Van Schaik, M. W. Hale, H. R. Irving, D. R. Whelan, J. A. Rathner   +7 more
doaj   +1 more source

Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

Molecular Metabolism, 2021
Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling protein 1
Subramanian Senthivinayagam, Vlad Serbulea, Clint M. Upchurch, Renata Polanowska-Grabowska, Suresh K. Mendu, Srabani Sahu, Prathiba Jayaguru, Kevin W. Aylor, Mahendra D. Chordia, Limor Steinberg, Nathaniel Oberholtzer, Seichii Uchiyama, Noriko Inada, Ulrike M. Lorenz, Thurl E. Harris, Susanna R. Keller, Akshaya K. Meher, Alexandra Kadl, Bimal N. Desai, Bijoy K. Kundu, Norbert Leitinger   +20 more
doaj   +1 more source

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice [PDF]

, 2016
The present study aimed to determine the effect of thyroid hormone dysfunction on brown adipose tissue activity and white adipose tissue browning in mice.
Hankir, Mohammed [u.v.m.], Klöting, Nora, Kranz, Mathias, Kunath, Anne, Köhrle, Josef, Rijntjes, Eddy, Steinhoff, Karen, Weiner, Juliane, Zeisig, Vilia   +8 more
core   +1 more source

Deceptive Brown Adipose Tissue

Journal of the ASEAN Federation of Endocrine Societies
A 23-year-old female presented with headache, palpitation, and hypertensive spells. There was no similar family history. Twenty-four (24) hour urine testing showed elevated normetanephrine level with normal metanephrines [metanephrines 123 mcg/24 hrs (74-297); normetanephrines 5321.16 mcg/24 hrs (73-808)].
Biswajit Payra, Abhranil Dhar, Pankaj Singhania, Akshay Khatri, Pranab Kumar Sahana   +4 more
openaire   +3 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

Molecular Metabolism, 2019
Objective: Increasing the amounts of functionally competent brown adipose tissue (BAT) in adult humans has the potential to restore dysfunctional metabolism and counteract obesity.
Naja Z. Jespersen, Amir Feizi, Eline S. Andersen, Sarah Heywood, Helle B. Hattel, Søren Daugaard, Lone Peijs, Per Bagi, Bo Feldt-Rasmussen, Heidi S. Schultz, Ninna S. Hansen, Rikke Krogh-Madsen, Bente K. Pedersen, Natasa Petrovic, Søren Nielsen, Camilla Scheele   +15 more
doaj   +1 more source

Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation [PDF]

, 2019
Brown Adipose Tissue (BAT) is present in a significant number of adult humans and can be activated by exposure to cold. Measurement of active BAT presence, activity, and volume are desirable for determining the efficacy of potential treatments intended ...
Crandall, John P, Gajwani, Prateek, Mawhinney, Daniel D, O., Joo H, Sterzer, Fred, Wahl, Richard L   +5 more
core   +2 more sources