Results 141 to 150 of about 77,500 (299)

Identification of brown adipose tissue using MR imaging in a human adult with histological and immunohistochemical confirmation

, 2014
Objective: Manipulation of human brown adipose tissue (BAT) represents a novel therapeutic option for diabesity. The aim of our study was to develop and test a novel magnetic resonance (MR) imaging-based method to identify human BAT, delineate it from ...
Yeo, Y.C., Adesanya, Oludolapo, Hutchinson, CE, Hutchinson, C.E, Reddy, N.L., Jones, T.A, Jones, Terence A., Hutchinson, C.E., Wayte, S.C, McTernan, P.G, McTernan, PG, Sankar, S., Sankar, S, Reddy, N.L, Barber, TM, Adesanya, O., Yeo, Y.C, Hutchinson, Charles E., Yeo, YC, Tripathi, G, Adesanya, O, Sankar, Sailesh, Kumar, S., Tripathi, G., Jones, TA, Barber, T. M., Yeo, Yen C., Randeva, HS, Wayte, Sarah C., Reddy, NL, Tripathi, Gyanendra, Kumar, Sudhesh, Jones, T.A., Randeva, Harpal S., Reddy, Narendra Lakshmana, McTernan, P. G., Kumar, S, McTernan, P.G., Wayte, S.C., Barber, T.M., Randeva, H.S., Randeva, H.S, Wayte, SC   +42 more
core   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

Lipids, EarlyView.
ABSTRACT Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high‐density lipoprotein cholesterol (HDL‐c), in relation to obesity status remains insufficiently explored.
Larissa Esthefani Barros Cirino, Divanei Zaniqueli, Oscar Geovanny Enriquez‐Martinez, Camila Maciel de Oliveira, Alexandre da Costa Pereira, Jordana Herzog Siqueira, Rafael de Oliveira Alvim   +6 more
wiley   +1 more source

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

Medicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang, Wen‐Bi He, Huan Wang, Hao Wang, Wen‐Jun Fang, Meng‐Qian Li, Jiong‐Xing Huang, Fei‐Peng Chen, Hui‐Guo Wang, Lin Zhu, Xiao‐Guang Liu   +10 more
wiley   +1 more source

Six‐ and Twelve‐Month Changes in Body Composition and 24‐h Energy Expenditure After a Very Low‐Calorie Ketogenic Diet

Obesity, EarlyView.
ABSTRACT Objective This study assessed changes in body composition and 24‐h energy metabolism at 6 and 12 months after initiation of a 1‐month very low‐calorie ketogenic diet (VLCKD) in women with obesity. Methods Seventeen women with obesity who completed a 1‐month VLCKD underwent a 4‐week transition phase with carbohydrate reintroduction, followed by
Alessio Basolo, Paolo Piaggi, Valentina Angeli, Paola Fierabracci, Chiara Bologna, Giordano Paolucci, Guido Salvetti, Luca Chiovato, Jonathan Krakoff, Alberto Landi, Ferruccio Santini   +10 more
wiley   +1 more source

Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue

Chinese Medicine
Background Obesity has become a critical public health challenge worldwide. Prioritizing prevention and tackling root causes—rather than merely managing symptoms—is critical to curbing this pandemic.
Zhiqi Huang, Ziyang Zhao, Haonan Shi, Runcheng He, Qianqian Feng, Yang Geng, Lei Zhang, Ti Zhang, Zhenteng Yan, Zhanhong Jia, Yanyan Jiang, Jianning Sun, Ang Cai, Shifen Dong, Lin Yang   +14 more
doaj   +1 more source

Dietary Protein Reduction During Isocaloric Conditions Reduces Body Weight in Men With Overweight or Obesity

Obesity, EarlyView.
Protein restriction, while meeting minimum requirements, induced weight loss and increased FGF21 in men with obesity under isocaloric conditions, without caloric restriction. ABSTRACT Objective Dietary protein reduction increases plasma fibroblast growth factor 21 (FGF21) and energy requirements in lean men under eucaloric conditions.
Aslak E. Lyster, Amalie S. Frederiksen, Jacob K. Jensen, Annemarie Lundsgaard, Nicoline R. Andersen, Kasper S. Jørgensen, Daniela Weber, Lukas Nachtigall, Erik A. Richter, Andreas M. Fritzen, Bente Kiens   +10 more
wiley   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Brown adipose tissue

Best Practice & Research Clinical Endocrinology & Metabolism, 2016
openaire   +4 more sources