Results 151 to 160 of about 68,398 (313)

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Identification of Neuritin 1 as a local metabolic regulator of brown adipose tissue. [PDF]

Nat Commun
Sánchez-Feutrie M, Romero M, Veiga SR, Borràs-Ferré N, Berrow N, Ràfols M, Giménez N, Rodgers-Furones A, Sabaté-Pérez A, Rodríguez Pérez Á, Cataldo LR, Burghardt H, Sebastián D, Plana N, Hernández V, Alcaide LI, Reina Ó, Monte MJ, Marin JJG, Palacín M, Burcelin R, Antonson P, Gustafsson JA, Zorzano A.   +23 more
europepmc   +1 more source

Fat metabolism in brown adipose tissue in vivo

, 1970
Matthew J. Hardman, D. Hull
openalex   +2 more sources

Exclusive occurrence of thermogenin antigen in brown adipose tissue [PDF]

, 1982
Barbara Cannon, A. Hedin, Jan Nedergaard
openalex   +1 more source

Brown adipose tissue: The magic bullet? [PDF]

Obesity, 2017
Patrick Schrauwen, Wouter D. van Marken Lichtenbelt   +1 more
openaire   +3 more sources

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

Measuring Peripheral Tissue DHA Turnover Using a Novel 13C Enrichment Technique

Lipids, EarlyView.
ABSTRACT Recently, through the use of compound‐specific isotope analysis (CSIA), our lab validated the utility of 13C enrichment (δ13C) of docosahexaenoic acid (DHA) by using a very high δ13C in a diet switch study by measuring brain, liver, and plasma DHA turnover and half‐lives via high‐precision gas chromatography combustion isotope ratio mass ...
Brinley J. Klievik, Adam H. Metherel, Rodrigo Valenzuela, Richard P. Bazinet   +3 more
wiley   +1 more source

Metabolic signals in sleep regulation: the role of brown adipose tissue. [PDF]

Neurobiol Sleep Circadian Rhythms
Szentirmai É, Kapás L.
europepmc   +1 more source

Portein kinases in brown adipose tissue of developing rats. State of activation of protein kinase during development and cold exposure and its relationship to adenosine 3':5'-monophosphate, lipolysis, and heat production.

, 1977
Josef P. Skála, Brian L. Knight
openalex   +1 more source

Mesenchymal Stem Cell‐Engrafted Bacterial Cellulose and Graphene Oxide Scaffolds Enhance Peripheral Nerve Repair in a Rat Model

Macromolecular Materials and Engineering, EarlyView.
This study investigates the use of graphene oxide‐decorated bacterial cellulose (BC/GO) scaffolds combined with mesenchymal stem cells (MSCs) to enhance axonal regeneration after sciatic nerve injury in rats. Graphene oxide is embedded monodispersely into the BC fibrillar matrix.
Ismail Simsek, Semra Unal, Efecan Cekic, Ecem Dogan, Ozlem Kirazli, Ferhat Harman   +5 more
wiley   +1 more source