Results 171 to 180 of about 3,183,818 (254)

Deciphering the Presence of Active Interscapular Brown Adipose Tissue in Humans. [PDF]

Acta Physiol (Oxf)
Sanchez-Gomez J, Ruiz-Campos S, Chica-Perez A, Baena-Raya A, Acosta FM, Wolfrum C, Rensen PCN, Romacho T, Martinez-Tellez B.   +8 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Immune-Induced Fever and Psychogenic Hyperthermia Can Occur Independently of Uncoupling Protein 1-Mediated Brown Adipose Tissue Thermogenesis. [PDF]

Acta Physiol (Oxf)
Matsuwaki T, Harigai W, Maksimov V, Nakayama Y, Uchida K, Chambers JK, Yamanouchi K, Eskilsson A, Blomqvist A.   +8 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Gut microbiota, brown adipose tissue whitening, and obesity: nutritional modulators and metabolic crosstalk. [PDF]

Nutr Metab (Lond)
Ghodraty M, Fekri M, Kiani M, Esmaeel Zadegan S, Abdoli Rezaei S, Mousavi Gilani SS, Manafi Varkiani M, Ghafouri A, Mehrnia N, Amudi M, Khodayar Z, Jouya Talaei A, Baadkoubehazaveh M.   +12 more
europepmc   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Fueling or Fighting Cancer? The Thermogenic Paradox of Brown Adipose Tissue. [PDF]

Curr Obes Rep
Guerrero JJG, Encarnacion PC, Wang CH, Del Rosario MAS, Notarte KI, Zhou J, Hsieh YT, Wang WY, Chang CW, Li WC.   +9 more
europepmc   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Sex-Dependent S1P-Related Gene Expression in Brown Adipose Tissue Across Exercise and Thermal Conditions. [PDF]

Int J Mol Sci
Ozabrahamyan S, Nirengi S, Vidal P, Baer LA, Stanford KI.   +4 more
europepmc   +1 more source

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source