Results 181 to 190 of about 66,586 (258)

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

Experimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

Chaperone-mediated autophagy controls brown adipose tissue thermogenic activity. [PDF]

Sci Adv
Mestres-Arenas A, Quesada-López T, Blasco-Roset A, Gavaldà-Navarro A, Godoy-Nieto FJ, Cereijo R, Kaushik S, Diaz A, Giralt M, Villarroya F, Cuervo AM, Villarroya J.   +11 more
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Periodic fasting and refeeding re-shapes lipid saturation, storage, and distribution in brown adipose tissue. [PDF]

PLoS Biol
Zhang X, Jiang T, Wang C, Montenegro Vazquez VF, Wu D, Yang X, Le Q, Sun MS, Wang X, Yang XO, Pu J, Campen M, Feng C, Liu M.   +13 more
europepmc   +1 more source

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

Experimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett, James J McCormick, Kelli E King, Kristina‐Marie T Janetos, Nathalie V Kirby, Fergus K O'Connor, Glen P Kenny   +6 more
wiley   +1 more source

Myeloid GHSR Deficiency Protects Against Thermogenic Impairment in Aging Through Immune Remodeling of Brown Adipose Tissue. [PDF]

Cells
Han HW, Kim DM, Baratiboldaji R, Wang H, Liu Z, Shen Z, Jha DK, Teferra T, Septiningsih EM, Patil B, Sun Y.   +10 more
europepmc   +1 more source

The impact of biological sex and stroke volume constituents on heterogeneity in the Q̇$\dot{Q}$–V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$ relationship and skeletal muscle saturation during cycling

Experimental Physiology, EarlyView.
Abstract Interindividual variability in the cardiac output (Q̇$\dot{Q}$) to the rate of oxygen consumption (V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$) slope (Q̇$\dot{Q}$–V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$) in healthy males is related to stroke volume (SV); however, the impact of differences in left ventricular (LV) structure and function as well as ...
Adam N. Di Salvo, Sinan Osman, Jacob L. Schwartz, Nino Nikolovski, Robert F. Bentley   +4 more
wiley   +1 more source

11-Oxygenated Androgens Inhibit Brown Adipose Tissue Differentiation.

Endocrinology
Yuan Y, Steenbergen J, de Oliveira Santos Goulart A, Sabaté-Pérez A, Visser JA.   +4 more
europepmc   +1 more source

Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue. [PDF]

EMBO Rep
Jaeckstein MY, Fischer AW, Rissiek B, Staehler T, Heine M, Behrens J, Mann O, Pfeifer A, Magnus T, Schlein C, Worthmann A, Scheja L, Koch-Nolte F, Heeren J.   +13 more
europepmc   +1 more source

Acute and lifelong exercise modulate the tumorigenic potential of human lung cancer cells and their susceptibility to cisplatin

Experimental Physiology, EarlyView.
Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares, João P. Moura, Leonardo M. R. Ferreira, Ana Pedrosa, Pedro Filipe, Luís Rama, Ana M. Teixeira, Ana M. Urbano   +7 more
wiley   +1 more source