Results 171 to 180 of about 180,287 (345)

Brown adipose tissue

Best Practice & Research Clinical Endocrinology & Metabolism, 2016
openaire   +4 more sources

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

Brown adipose tissue identification in an adult human using IDEAL MRI [PDF]

, 2013
Narendra Reddy, T. Jones, Sarah Wayte, Oludolapo Adesanya, Yen Yeo, Harpal Randeva, Sudhesh Kumar, Charles Hutchinson, T. Barber   +8 more
openalex   +1 more source

Integrated Analysis of Transcriptome, microRNAs, and Chromatin Accessibility Revealed Potential Early B-Cell Factor1-Regulated Transcriptional Networks during the Early Development of Fetal Brown Adipose Tissues in Rabbits [PDF]

, 2022
Kun Du, Yu Shi, Xue Bai, Li Chen, Wenqiang Sun, Shiyi Chen, Jie Wang, Xianbo Jia, Songjia Lai   +8 more
openalex   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Overexpressing the hydroxycarboxylic acid receptor 1 in mouse brown adipose tissue restores glucose tolerance and insulin sensitivity in diet-induced obese mice

, 2022
Hyeon-Young Min, Jiyeon Hwang, Yuna Choi, Young‐Hwan Jo   +3 more
openalex   +2 more sources

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham, KayLene Y. H. Yamada, Emma M. Rhodes, Agata. M. Rudolf, Wendy R. Hood   +4 more
wiley   +1 more source

Brown adipose tissue

, 2015
Anna Maffione, Arlene Campos, Mostafa Elfeky   +2 more
openaire   +2 more sources

Protocol for the injection of adenoviruses into brown adipose tissue in mice. [PDF]

STAR Protoc
Prida E, Vázquez-Durán JA, Muñoz-Moreno D, Díaz-Garzón L, Torres Caldas AM, Seoane LM, Quiñones M, Pardo M, Al-Massadi O.   +8 more
europepmc   +1 more source