Summary Background Plasma L‐lactate (lactate) is widely used as a prognostic marker in horses with acute gastrointestinal disease (colic), but association with obesity is unclear. In humans, plasma lactate is correlated with obesity and insulin resistance. Objectives This study aims to evaluate the association of obesity (body condition score ≥7/9) and
A. L. Tillisch +4 more
wiley +1 more source
A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor. [PDF]
Du X +14 more
europepmc +1 more source
The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Author Correction: The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue. [PDF]
Wang S +10 more
europepmc +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Diet and temperature interactively impact brown adipose tissue gene regulation controlled by DNA methylation. [PDF]
Hagemann T +9 more
europepmc +1 more source
The Anti-Obesity Effect of Fish Oil in Diet-Induced Obese Mice Occurs via Both Decreased Food Intake and the Induction of Heat Production Genes in Brown but Not White Adipose Tissue [PDF]
Takahiko Obo +12 more
openalex +1 more source
Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs
ABSTRACT Reproductive traits related to litter size are the main indicators of reproductive efficiency in pig production and are continuously evaluated for the selection of maternal lines. Several environmental and genetic factors are involved with the development of these traits.
Guilherme Oselame +10 more
wiley +1 more source
Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue. [PDF]
Jaeckstein MY +13 more
europepmc +1 more source
Abstract Here, we describe a new species of Peckoltia (Loricariidae; Hypostominae) from the rapids of the Rio Tocantins‐Araguaia basin, previously identified as Peckoltia vittata, using an integrative taxonomy approach. The new species is distinguished from congeners by ventral region presenting diffuse stripes on surface, not presenting spots or ...
Felipe Arian Andrade de Araújo +3 more
wiley +1 more source

