Results 21 to 30 of about 292,612 (343)

Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.

Cell Metabolism, 2018
Skeletal muscle and brown adipose tissue (BAT) are functionally linked, as exercise increases browning via secretion of myokines. It is unknown whether BAT affects muscle function. Here, we find that loss of the transcription factor IRF4 in BAT (BATI4KO)
X. Kong, Ting Yao, P. Zhou, L. Kazak, Danielle E. Tenen, A. Lyubetskaya, Brian A. Dawes, Linus T. Tsai, B. Kahn, B. Spiegelman, Tiemin Liu, E. Rosen   +11 more
semanticscholar   +3 more sources

Identification and importance of brown adipose tissue in adult humans.

New England Journal of Medicine, 2009
A. Cypess, S. Lehman, Gethin Williams, Ilan Tal, D. Rodman, A. Goldfine, F. Kuo, E. Palmer, Y. Tseng, A. Doria, G. Kolodny, R. Kahn   +11 more
semanticscholar   +3 more sources

Cold-activated brown adipose tissue in healthy men.

New England Journal of Medicine, 2009
W. D. van Marken Lichtenbelt, Joost W. Vanhommerig, N. M. Smulders, Jamie Drossaerts, Gerrit J. Kemerink, N. D. Bouvy, Patrick Schrauwen, G. J. J. Teule   +7 more
semanticscholar   +3 more sources

ELOVL3 regulates phospholipid homeostasis and thermogenesis in brown adipose tissue. [PDF]

J Lipid Res
Qin Z, Wang P, Lu M, Tang Y, Ren Q, Chen FJ, Zhang WJ, Wei C.   +7 more
europepmc   +3 more sources

Changes in circulating bile acid levels during cold exposure are associated with brown adipose tissue in humans: a secondary analysis from the ACTIBATE study. [PDF]

J Physiol Biochem
Jurado-Fasoli L, Martinez-Tellez B, Kohler I, Ruiz JR, Osuna-Prieto FJ.   +4 more
europepmc   +2 more sources

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Reviews in Endocrine & Metabolic Disorders, 2023
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregulation.
Zeinab Ghesmati, Mohsen Rashid, S. Fayezi, F. Gieseler, E. Alizadeh, Masoud Darabi   +5 more
semanticscholar   +1 more source

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

Frontiers in Endocrinology, 2023
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy expenditure, has been extensively studied as a potential avenue to combat obesity.
K. Ziqubu, P. Dludla, S. Mthembu, B. Nkambule, S. Mabhida, B. Jack, T. M. Nyambuya, S. Mazibuko-Mbeje   +7 more
semanticscholar   +1 more source

Brown Adipose Tissue—A Translational Perspective

Endocrine reviews, 2022
Brown adipose tissue (BAT) displays the unique capacity to generate heat through uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for cardiometabolic diseases.
A. Carpentier, D. Blondin, F. Haman, D. Richard   +3 more
semanticscholar   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

Adipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng, Jingkang Wang, Hongyu Dai, Yuhui Duan, Yongcheng An, Lu Shi, Ying-lan Lv, Huimin Li, Chen Wang, Quantao Ma, Yaqi Li, Pengfei Li, Haifeng Du, Baosheng Zhao   +13 more
semanticscholar   +1 more source

Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis

International Journal of Molecular Sciences, 2021
The increased worldwide prevalence of obesity, insulin resistance, and their related metabolic complications have prompted the scientific world to search for new possibilities to combat obesity.
K. Maliszewska, A. Krętowski
semanticscholar   +1 more source