Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.
PLoS ONE, 2015 BST-2 (tetherin, CD317, HM1.24) restricts virus growth by tethering enveloped viruses to the cell surface. The role of BST-2 during influenza A virus infection (IAV) is controversial.
Sarah L Londrigan +10 more
doaj +1 more source
Sonophotocatalytic water splitting by BaTiO3@SrTiO3 core shell nanowires
Ultrasonics Sonochemistry, 2023 Sonophotocatalysis has garnered significant attention due to its potential to enhance advanced oxidation processes, particularly water splitting, by employing materials with combined sonocatalytic and photocatalytic properties.
Harshavardhan Mohan +2 more
doaj +1 more source
HIV-1 BF intersubtype recombinant Vpu second alpha helix plays an important role in the viral release and BST-2 degradation [PDF]
, 2013 We previously reported a naturally occurring BF intersubtype recombinant Vpu variant with augmented capacity to enhance viral replication. Structural analysis of this variant revealed that its transmembrane domain (TMD) and α-helix I in the cytoplasmic ...
Carobene, Mauricio +4 more
core +1 more source
PLoS Pathogens, 2009 The interferon-induced transmembrane protein BST-2/CD317 (tetherin) restricts the release of diverse enveloped viruses from infected cells. The HIV-1 accessory protein Vpu antagonizes this restriction by an unknown mechanism that likely involves the down-
Richard S Mitchell +9 more
doaj +1 more source
KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant [PDF]
, 2015 Dopamine D-4 Receptor Polymorphism : The dopamine D-4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit ...
Lintermans, Béatrice +3 more
core +4 more sources
BST-2 mediated restriction of simian–human immunodeficiency virus
Virology, 2010 Pathogenic simian-human immunodeficiency viruses (SHIV) contain HIV-1 Vpu and SIV Nef, both shown to counteract BST-2 (HM1.24; CD317; tetherin) inhibition of virus release in a species-specific manner. We show that human and pig-tailed BST-2 (ptBST-2) restrict SHIV.
Ruiz, Autumn +6 more
openaire +2 more sources
Development and Characterization of the Shortest Anti-Adhesion Peptide Analogue of B49Mod1
Molecules, 2020 Inhibition of cancer cell adhesion is an effective approach to killing adherent cancer cells. B49 and its analog B49Mod1 peptides, derived from the extracellular domain (ECD) of bone marrow stromal antigen 2 (BST-2), display anti-adhesion activity on ...
Yuan Lyu +2 more
doaj +1 more source
Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins. [PDF]
, 2019 The plasma membrane is a site of conflict between host defenses and many viruses. One aspect of this conflict is the host's attempt to eliminate infected cells using innate and adaptive cell-mediated immune mechanisms that recognize features of the ...
Guatelli, John +5 more
core +1 more source
Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/Tetherin [PDF]
AIDS Research and Human Retroviruses, 2009 Pathogenic microorganisms encode proteins that antagonize specific aspects of innate or adaptive immunity. Just as the study of the HIV-1 accessory protein Vif led to the identification of cellular cytidine deaminases as host defense proteins, the study of HIV-1 Vpu recently led to the discovery of the interferon-induced transmembrane protein BST-2 ...
Andrey, Tokarev +3 more
openaire +2 more sources
Viruses, 2016 BST-2/tetherin blocks the release of various enveloped viruses including HIV-1 with a “physical tethering” model. The detailed contribution of N-linked glycosylation to this model is controversial.
Zhu Han +6 more
doaj +1 more source