Results 51 to 60 of about 18,811 (223)

Upregulation of BST-2/Tetherin by HIV Infection In Vivo [PDF]

Journal of Virology, 2011
ABSTRACT The interferon-inducible antiviral factor BST-2 prevents several enveloped viruses, including HIV, from escaping infected cells. The HIV protein Vpu antagonizes this host defense. Little is known about the expression of BST-2 during HIV infection in vivo and whether it can be modulated to the host'
Stefanie, Homann, Davey, Smith, Susan, Little, Douglas, Richman, John, Guatelli   +4 more
openaire   +3 more sources

Single Amino Acid Substitution N659D in HIV-2 Envelope Glycoprotein (Env) Impairs Viral Release and Hampers BST-2 Antagonism

Viruses, 2016
BST-2 or tetherin is a host cell restriction factor that prevents the budding of enveloped viruses at the cell surface, thus impairing the viral spread. Several countermeasures to evade this antiviral factor have been positively selected in retroviruses:
François E. Dufrasne, Catherine Lombard, Patrick Goubau, Jean Ruelle   +3 more
doaj   +1 more source

Passing through the bounce in the ekpyrotic models [PDF]

, 2001
By considering a simplified but exact model for realizing the ekpyrotic scenario, we clarify various assumptions that have been used in the literature.
A. Borde, A. Lukas, A. Lukas, A. Lukas, A.H. Guth, C. Barceló, D.H. Lyth, D.H. Lyth, Dominik J. Schwarz, E.B. Bogomol’nyi, G. Veneziano, I. Antoniadis, J. Hwang, J. Hwang, J. Hwang, J. Khoury, J. Khoury, J. Martin, J. Martin, J. Preskill, J.E. Lidsey, J.M. Bardeen, Jérôme Martin, L. Randall, L. Randall, L. Randall, L.A. Wu, L.F. Abbott, M. Gasperini, M. Visser, M.K. Prasad, N. Arkani-Hamed, N. Arkani-Hamed, N. Deruelle, Nelson Pinto-Neto, P. Hořava, P. Hořava, P. Peter, P.J. Steinhardt, Patrick Peter, R. Brandenberger, R. Kallosh, R. Kallosh, R.H. Brandenberger, S. Carlip, V.F. Mukhanov, Ya.B. Zel’dovich   +46 more
core   +2 more sources

Single Center Experience of the Balloon-Stent Technique for the Treatment of Unruptured Distal Internal Carotid Artery Aneurysms: Sharing a Simple and Reliable Tip to Use Scepter-Atlas Combination

대한영상의학회지, 2021
Purpose The balloon-stent technique (BST) has certain strengths as an assisted technique for the treatment of complex aneurysms. After Atlas release, the BST can be executed without an exchange maneuver of the balloon to the stent-delivery catheter ...
Yu-jung Park, Jieun Roh, Seung Kug Baik, Jeong A Yeom, Chul-Hoo Kang, Hee Seok Jeong, Sang Won Lee   +6 more
doaj   +1 more source

Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo

Retrovirology, 2012
Background Bone marrow stromal cell antigen 2 (BST-2) is a cellular factor that restricts the egress of viruses such as human immunodeficiency virus (HIV-1) from the surface of infected cells, preventing infection of new cells.
Jones Philip H, Mehta Harshini V, Maric Martina, Roller Richard J, Okeoma Chioma M   +4 more
doaj   +1 more source

Tetherin inhibits prototypic foamy virus release [PDF]

, 2011
Background: Tetherin (also known as BST-2, CD317, and HM1.24) is an interferon- induced protein that blocks the release of a variety of enveloped viruses, such as retroviruses, filoviruses and herpesviruses. However, the relationship between tetherin and
Chen Liang, Dan Xu, Fengwen Xu, Juan Tan, Ruikang Liu, Wentao Qiao, Yue Li, Yunqi Geng   +7 more
core   +3 more sources

Antagonism to human BST-2/tetherin by Sendai virus glycoproteins

Journal of General Virology, 2013
Tetherin is an interferon-inducible factor that restricts viral particle production. We show here that Sendai virus (SeV) induces a drastic decrease in tetherin levels in infected HeLa cells. Using ectopic expression of tetherin in Madin–Darby canine kidney cells, we find that infectious SeV production is sensitive to restriction by tetherin ...
Bampi, Carole, Rasga, Lara, Roux, Laurent   +2 more
openaire   +3 more sources

Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors [PDF]

, 2010
Background The gibbon ape leukemia virus (GaLV) Env protein mediates entry into a wide range of human cells and is frequently used to pseudotype retroviral vectors.
Ilias Christodoulopoulos, Magali E Droniou-Bonzom, Jill E Oldenburg, Paula M Cannon   +3 more
core   +2 more sources

The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation.

PLoS Pathogens, 2011
The Endosomal Sorting Complexes Required for Transport (ESCRT) machinery, a highly conserved set of four hetero-oligomeric protein complexes, is required for multivesicular body formation, sorting ubiquitinylated membrane proteins for lysosomal ...
Katy Janvier, Annegret Pelchen-Matthews, Jean-Baptiste Renaud, Marina Caillet, Mark Marsh, Clarisse Berlioz-Torrent   +5 more
doaj   +1 more source

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species [PDF]

, 2009
In this study, we first demonstrate that endogenous hBST-2 is predominantly expressed on the plasma membrane of a human T cell line, MT-4 cells, and that Vpu-deficient HIV-1 was less efficiently released than wild-type HIV-1 from MT-4 cells. In addition,
Kei Sato, Seiji P Yamamoto, Naoko Misawa, Takeshi Yoshida, Takayuki Miyazawa, Yoshio Koyanagi   +5 more
core   +1 more source