Results 71 to 80 of about 18,811 (223)

Site-Directed Mutagenesis of HIV-1 vpu Gene Demonstrates Two Clusters of Replication-Defective Mutants with Distinct Ability to Down-Modulate Cell Surface CD4 and Tetherin [PDF]

, 2010
HIV-1 Vpu acts positively on viral infectivity by mediating CD4 degradation in endoplasmic reticulum and enhances virion release by counteracting a virion release restriction factor, tetherin.
Masako Nomaguchi, Naoya Doi, Sachi Fujiwara, Mikako Fujita, Akio Adachi   +4 more
core   +1 more source

Efecto del reemplazo folicular (GnRH) y de somatotropina bovina (bST) sobre la fertilidad de vacas lecheras expuestas a estrés calórico

Revista Mexicana de Ciencias Pecuarias, 2020
Tres protocolos reproductivos fueron evaluados: 1) PG: inyección de PGF2α en el día 50 posparto e inseminación (IA) en base a detección del estro. 2) OVS (Ovsynch: día 0, GnRH; día 7, PGF2α; día 9, GnRH; día 10, IA); y 3) ROV (GnRH + Ovsynch: día- 7 ...
Renato Raúl Lozano-Domínguez, Carlos Fernando Aréchiga-Flores, Marco Antonio López-Carlos, Zimri Cortés-Vidauri, Melba Rincón-Delgado, José Ma. Carrera-Chávez, Ulises Macías-Cruz, Joel Hernández-Cerón   +7 more
doaj   +1 more source

Manipulating Atomic Disorder and Mesoscale Architectures for High‐Efficiency Thermoelectric Modules

Advanced Science, EarlyView.
The in situ reaction of PbTiO3 precursor reacts in situ with the Bi0.5Sb1.5Te3 matrix, effectively enlarging the energy barrier for minority carrier excitation and suppressing bipolar diffusion, and predominantly scattering mid‐to‐low frequency phonons. Ultimately, a single thermoelectric module was fabricated to achieve a competitive efficiency of ∼7%
Jiwu Xin, Bo Wang, Chengyun Xu, Wang Li, Pengyu Zhang, Dongwang Yang, Yongke Wang, Jinfeng Dong, Lei Wei, Ting Zhang, Qinghui Jiang   +10 more
wiley   +1 more source

Coupled Vacancy and Phonon‐Scattering Engineering Drive Defect Evolution Toward Multifunctional High‐Performance Bi2Te3 Thermoelectrics

Advanced Science, EarlyView.
ZnSb reduces carrier concentration and suppresses Te volatilization, while Se substitution within QLs softens phonons and enhances anharmonicity. Swapped bilayers near twin boundaries strengthen phonon scattering and interlayer bonding. As a result, the optimal sample achieves an ultra‐high zT ∼1.51, cooling temperature difference of ∼70 K, power ...
Ruiheng Li, Minwen Yang, Huangshui Ma, Jie Zheng, Shengqiang Cui, Xiaobo Tan, Xuri Rao, Xiang An, Zongxiang Kan, Siqi Huo, Jing Shuai, Min Hong, Ran Ang   +12 more
wiley   +1 more source

Tetherin restricts direct cell-to-cell infection of HIV-1 [PDF]

, 2010
Background Tetherin (BST-2/CD317/HM1.24) is an interferon (IFN)-inducible factor of the innate immune system, recently shown to exert antiviral activity against HIV-1 and other enveloped viruses by tethering nascent viral particles to the ...
Björn D Kuhl, Richard D Sloan, Daniel A Donahue, Tamara Bar-Magen, Chen Liang, Mark A Wainberg   +5 more
core   +1 more source

Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration [PDF]

Proceedings of the National Academy of Sciences, 2009
Tetherin is an IFN-inducible restriction factor that inhibits HIV-1 particle release in the absence of the HIV-1 countermeasure, viral protein U (Vpu). Although ubiquitous in HIV-1 and simian immunodeficiency viruses from chimpanzees, greater spot nosed monkeys, mustached monkeys, and Mona monkeys, other primate lentiviruses do not encode a Vpu protein.
Gupta, R. K., Mlcochova, P., Pelchen-Matthews, A., Petit, S. J., Mattiuzzo, G., Pillay, D., Takeuchi, Y., Marsh, M., Towers, G. J.   +8 more
openaire   +2 more sources

Direct restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particles.

PLoS Pathogens, 2010
Investigation of the Vpu protein of HIV-1 recently uncovered a novel aspect of the mammalian innate response to enveloped viruses: retention of progeny virions on the surface of infected cells by the interferon-induced, transmembrane and GPI-anchored ...
Kathleen Fitzpatrick, Mark Skasko, Thomas J Deerinck, John Crum, Mark H Ellisman, John Guatelli   +5 more
doaj   +1 more source

The dielectric and ferroelectric properties of (Ba0.5Sr0.5)TiO3-doped (Bi0.5Na0.5)TiO3 lead-free ceramics [PDF]

Journal of Advanced Dielectrics, 2017
This work prepares (Ba0.5Sr0.5)TiO3 (BST)-doped (Bi1∕2Na1∕2)TiO3 (NBT) lead free ceramics through conventional solid reaction method and analyzes the doping effect of BST on phases, microstructure, dielectric and ferroelectric properties.
Guoliang Xue, Qiankun Wu, Gang Li, Huaizhou Lin, Gang Liu, Yi Chen, Xiaokui Liu, Yan Yan   +7 more
doaj   +1 more source

Multifunctional TiO2‐Graphene Hybrid Interfaces for Printable High‐Energy‐Density Polymer Thin Film Capacitor

Advanced Electronic Materials, EarlyView.
ABSTRACT The rapid advancement of flexible and wearable electronics demands printable thin‐film capacitors that combine high dielectric performance with scalable fabrication. However, achieving this balance in polymer dielectrics remains challenging, as enhancements in dielectric constant typically come at the expense of increased loss and reduced ...
Yujia Fan, Yujia Li, Ruixiang Li, Shaoliang Guan, Mengyan Nie, Shahab Akhavan, Buddha Deka Boruah, Mingqing Wang   +7 more
wiley   +1 more source

Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles

Chemistry – A European Journal, EarlyView.
A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook, Blandine McKay, Craig Jamieson, Lee J. Edwards, Charlotte Harriman, Zackary S. Read, Simon T. Bate   +6 more
wiley   +1 more source