Results 101 to 110 of about 8,611 (185)

The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases [PDF]

, 2015
Dendritic cells (DCs) are key antigen-presenting cells that have an important role in autoimmune pathogenesis. DCs control both steady-state T cell tolerance and activation of pathogenic responses.
Abram, Akdis, Anandasabapathy, Asano, Aumeunier, Baban, Bacchetta, Bailey, Bailey-Bucktrout, Balasa, Banchereau, Bartholome, Belkaid, Berer, Bhattacharya, Billiard, Blasius, Blasius, Bonifaz, Boscardin, Bour-Jordan, Bourges, Bradshaw, Bresson, Calderon, Carrero, Chaussabel, Chen, Cheong, Chilton, Crozat, Darrasse-Jeze, den Haan, Diana, Diana, Dudziak, Dunne, Dzionek, Ferris, Finkelman, Furie, Gallo, Ghaemi Oskouie, Goverman, Gregori, Greter, Guilliams, Gulden, Gulden, Gupta, Hamilton-Williams, Hamilton-Williams, Hammer, Hawiger, Hawiger, Herold, Hildner, Hu, Idoyaga, Irla, Isaksson, Ivakine, Ivanov, Jakubzick, Ji, Kalunian, Kaneko, Katz, Kim, Kim, Kostic, Kriegel, Kriegel, Lau-Kilby, Lee, Lenschow, Li, Loschko, Loschko, Luo, Maraskovsky, Markle, Marleau, Martin, Mastrandrea, McMahon, Merrill, Morel, Mukhopadhaya, Nakano, Neubert, Nussenzweig, Ohnmacht, Orban, Orban, Pakala, Pelletier, Poligone, Poulin, Price, Price, Prinz, Reboulet, Richer, Richer, Ring, Rowland, Saeki, Salomon, Santin, Saxena, Schallenberg, Scroggins, Serbina, Shoda, Soares, Sosa, Stranges, Tai, Takaki, Tarbell, Tarbell, Teichmann, Theofilopoulos, Timper, Todd, Turner, Van Belle, Van Belle, Vasquez, Wang, Wang, Welzen-Coppens, Welzen-Coppens, Wen, Wlodarczyk, Wu, Wu, Xia, Yamanouchi, Yamazaki, Yamazaki, Yang, Yen, Yurkovetskiy, Zheng   +145 more
core   +2 more sources

Rab7A is required for efficient production of infectious HIV-1.

PLoS Pathogens, 2011
Retroviruses take advantage of cellular trafficking machineries to assemble and release new infectious particles. Rab proteins regulate specific steps in intracellular membrane trafficking by recruiting tethering, docking and fusion factors, as well as ...
Marina Caillet, Katy Janvier, Annegret Pelchen-Matthews, Delphine Delcroix-Genête, Grégory Camus, Mark Marsh, Clarisse Berlioz-Torrent   +6 more
doaj   +1 more source

Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease

Asian Pacific Journal of Tropical Medicine
id="st1" To explore which pattern recognition receptors (PRRs) play a key role in the development of hand, foot, and mouth disease (HFMD) by analyzing PRR-associated genes. id="st2" We conducted a comparative analysis of PRR-associated gene expression in
Muqi Wang, Huiling Deng, Yuan Chen, Yikai Wang, Yufeng Zhang, Chenrui Liu, Meng Zhang, Ting Li, Shuangsuo Dang, Yaping Li   +9 more
doaj   +1 more source

Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated Neuroinflammation

Frontiers in Microbiology, 2018
HTLV-1-Associated Myelopathy (HAM/TSP) is a progressive neuroinflammatory disorder for which no disease-modifying treatment exists. Modest clinical benefit from type I interferons (IFN-α/β) in HAM/TSP contrasts with its recently identified IFN-inducible ...
Fabio E. Leal, Fabio E. Leal, Soraya Maria Menezes, Emanuela A. S. Costa, Phillip M. Brailey, Lucio Gama, Aluisio C. Segurado, Esper G. Kallas, Douglas F. Nixon, Tim Dierckx, Ricardo Khouri, Ricardo Khouri, Jurgen Vercauteren, Bernardo Galvão-Castro, Rui Andre Saraiva Raposo, Johan Van Weyenbergh   +15 more
doaj   +1 more source

Reduced Type‐I Interferon by Plasmacytoid Dendritic Cells and Asthma in School‐Aged Children

Allergy, Volume 81, Issue 1, Page 109-120, January 2026.
Low type‐I interferon response to in vitro stimulation of plasmacytoid dendritic cells (pDC) with a TLR7/8 agonist (R848) is associated with current asthma in school‐aged children. Low type‐I interferon response is associated with increased level of atopy but appears to have limited impact on early life viral infection susceptibility.
Isabelle Coenen, Anya C. Jones, Alice A. White, Mari Takashima, Wen Ray Lee, Matthew D. Wong, Dwan Vilcins, Ulrich Kadolsky, Ali Sadiq Cheema, Alka Saxena, Anthony Bosco, Keith Grimwood, Peter D. Sly, Deborah H. Strickland, Jonatan Leffler   +14 more
wiley   +1 more source

Variational optimization algorithms for uniform matrix product states [PDF]

, 2018
We combine the density matrix renormalization group (DMRG) with matrix product state tangent space concepts to construct a variational algorithm for finding ground states of one-dimensional quantum lattices in the thermodynamic limit.
Fishman, MT, Haegeman, Jutho, Vanderstraeten, Laurens, Verstraete, Frank, Zauner-Stauber, V   +4 more
core   +4 more sources

Long non-coding RNA BST2/BISPR is induced by IFN and regulates the expression of the antiviral factor Tetherin

Frontiers in Immunology, 2015
Many long non-coding RNAs (lncRNAs) are expressed in cells but only a few have been well characterized. In these cases, lncRNAs have been shown to be key regulators of several cellular processes.
Marina eBarriocanal, Elena eCarnero, Victor eSegura, Puri eFortes   +3 more
doaj   +1 more source

Mechanisms underlying HIV-1 Vpu-mediated viral egress

Frontiers in Microbiology, 2014
Viruses such as lentiviruses that are responsible for long lasting infections, have to evade several level of cellular immune mechanisms to persist and efficiently disseminate in the host.
Nicolas eRoy, Grégory ePacini, Clarisse eBerlioz-Torrent, Katy eJanvier   +3 more
doaj   +1 more source

A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24. [PDF]

J Biol Chem
AbstractThe introduction of combined antiretroviral therapy (cART) has greatly improved the quality of life of human immunodeficiency virus type 1 (HIV-1)-infected individuals. Nonetheless, the ever-present desire to seek out a full remedy for HIV-1 infections makes the discovery of novel antiviral medication compelling. Owing to this, a new late-stage
Nyame P, Togami A, Yoshida T, Masunaga T, Begum MM, Terasawa H, Monde N, Tahara Y, Tanaka R, Tanaka Y, Appiah-Kubi J, Amesimeku WAO, Hossain MJ, Otsuka M, Yoshimura K, Ikeda T, Sawa T, Satou Y, Fujita M, Maeda Y, Tateishi H, Monde K.   +21 more
europepmc   +3 more sources

Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium [PDF]

, 2018
For the second time, the HIV Cure Research Center (HCRC) at Ghent University organised the HIV Cure and Reservoir Symposium, in Ghent, Belgium, where in this two-day conference, virologists, molecular biologists, immunologists and clinicians presented ...
Cole, Basiel, Kint, Sam, Sips, Magdalena, Van Hecke, Clarissa, Vandekerckhove, Linos   +4 more
core   +1 more source