Results 81 to 90 of about 8,611 (185)

Antigen Delivery to Plasmacytoid Dendritic Cells via BST2 Induces Protective T Cell-Mediated Immunity [PDF]

open access: yesThe Journal of Immunology, 2011
Abstract Plasmacytoid dendritic cells (PDCs) are capable of presenting Ags to T cells in a tolerogenic or immunogenic manner depending on the formulation of the Ag and the mode of stimulation. It has not been investigated whether effective adaptive immune responses useful for vaccination can be induced by Ab-mediated Ag targeting to PDCs
Jakob, Loschko   +7 more
openaire   +2 more sources

Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity

open access: yesFrontiers in Cell and Developmental Biology, 2022
Abdominal obesity associates with cardiometabolic disease and an accumulation of lipids in the visceral adipose depot, whereas lipid accumulation in the subcutaneous depot is more benign.
Neha Mathur   +12 more
doaj   +1 more source

Spatiotemporal Transcriptomics Characterizes Immune Microenvironment During Mouse Liver Aging

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
T cells are the most dynamically altered immune population in the aged liver. Accumulation of CD8+ Tex in aged livers. Spatial enrichment of CD8+ Tex in the portal vein zone. PP hepatocytes promote T cell exhaustion via Lpin1. T cell exhaustion correlates with liver disease progression.
Jiahua Lu   +7 more
wiley   +1 more source

HIV and innate immunity ? a genomics perspective [PDF]

open access: yes, 2013
Innate immunity is a theme of increasing interest for HIV research. However, the term is overstretched to cover biological barriers, cellular systems, soluble factors, signaling pathways, and effectors and is inconsistently applied.
McLaren, P.J., Rausell, A., Telenti, A.
core   +1 more source

Use and characterization of personal psychotherapy by psychiatrists: Findings from a questionnaire survey in a sample of consultant and trainee psychiatrists in Ireland

open access: yesBritish Journal of Psychotherapy, Volume 42, Issue 2, Page 145-161, May 2026.
Abstract Existing research suggests that personal therapy positively contributes to the continued personal well‐being and ongoing professional development of mental health professionals, including psychiatrists. The aim of this research is to examine the use and characterization of personal therapy by consultant and trainee psychiatrists based in ...
R.E. Aubry   +3 more
wiley   +1 more source

Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2

open access: yesCell Death Discovery, 2021
Mesenchymal stem cells (MSCs) show significant therapeutic effects in type 1 diabetes mellitus (T1DM) as regulating the inflammatory processes. However, little is known about the detailed process of MSCs immunosuppression in T1DM.
Na Zhou   +7 more
doaj   +1 more source

Integrating Flow Cytometry in the Diagnostic Work of HIV‐Associated Hodgkin's Lymphomas

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Hodgkin lymphoma (HL) is prevalent worldwide and typically presents symptoms like sudden pain, swelling, and weight loss. Classical HL (cHL) is largely treatable with modern risk‐adapted and response‐based therapy. cHL represents one of the most common malignancies occurring during the course of evolution in patients living with HIV.
Maria Santa   +23 more
wiley   +1 more source

Hepatitis E Virus (HEV) egress: Role of BST2 (Tetherin) and interferon induced long non- coding RNA (lncRNA) BISPR.

open access: yesPLoS ONE, 2017
BackgroundThe biology of Hepatitis E Virus (HEV), a common cause of epidemic and sporadic hepatitis, is still being explored. HEV exits liver through bile, a process which is essential for its natural transmission by feco-oral route.
Daizy Paliwal   +2 more
doaj   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang   +10 more
wiley   +1 more source

Innate immune defects in HIV permissive cell lines. [PDF]

open access: yes, 2016
Primary CD4+ T cells and cell lines differ in their permissiveness to HIV infection. Impaired innate immunity may contribute to this different phenotype. We used transcriptome profiling of 1503 innate immunity genes in primary CD4+ T cells and permissive
Ciuffi, A.   +5 more
core   +4 more sources

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