Results 61 to 70 of about 6,331 (185)
Med Research, EarlyView.This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang +4 more
wiley +1 more source
BST2 is present in HCMV virions.
, 2013 A) HCMV preparations were separated by a discontinuous (5–50%) Nycodenz gradient and equal-sized fractions were isolated prior to spectrophotometric analysis of total DNA. B) Immunoblot for IE1 or GAPDH of HFFs infected with each of the fractions.
Mandana Mansouri (340371) +5 more
core +1 more source
Effect of dietary supplementation with β-hydroxy-β-methylbutyrate on stress parameters in goat kids
Revista Brasileira de Zootecnia, 2020 The objective of this study was to determine the effect of dietary supplementation with β-hydroxy-β-methylbutyric acid (HMB) on live weight loss and selected blood parameters in goat kids after transportation to the slaughterhouse.
Janina Sowińska +6 more
doaj +1 more source
Allergy, EarlyView.Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri +11 more
wiley +1 more source
Viruses, 2019 The measles virus (MeV), a member of the genus Morbillivirus, is an established pathogen of humans. A key feature of morbilliviruses is their ability to spread by virus−cell and cell−cell fusion.
James T. Kelly +10 more
doaj +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
PLoS ONE, 2017 BackgroundThe biology of Hepatitis E Virus (HEV), a common cause of epidemic and sporadic hepatitis, is still being explored. HEV exits liver through bile, a process which is essential for its natural transmission by feco-oral route.
Daizy Paliwal +2 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 9, Page 2323-2339, September 2026.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Detection of BST2 proteins and glycosylation analysis.
, 2015 (A) SDS-PAGE analysis of BST2 mutants under denaturing conditions. 293T cells and CrFk cells were transfected with 500 ng of fBST2, fBST2 N79A, fBST2 N119A, fBST2 N79/119A, fBST2-IHA, fBST2-NHA and fBST2*. After 48 h, cells were harvested and analyzed by
Bin Yu (14464) +10 more
core +1 more source
, 2022 Bone Marrow Stromal Cell Antigen 2 (BST2) is a type II transmembrane protein expressed on various cell types that tethers the release of viruses.
Soo Kyung Jeong +9 more
core +1 more source