Results 41 to 50 of about 6,331 (185)

Effects of BST2 knockdown by siRNA on BST2 expression in hAD-BMSCs.

open access: yes, 2016
RT-PCR and immunoblotting analyses (A) as well as qRT-PCR (B) demonstrated that the expression of BST2 was lower in cells treated for 5 days with OS and siBST2 #1 or #2 than in cells treated with OS and non-targeting siRNA (siCont).
Hyun-Dae Lim (3160980)   +8 more
core   +1 more source

Aberrant regulation of the BST2 (Tetherin) promoter enhances cell proliferation and apoptosis evasion in high grade breast cancer cells.

open access: yesPLoS ONE, 2013
Normal cellular phenotypes that serve an oncogenic function during tumorigenesis are potential candidates for cancer targeting drugs. Within a subset of invasive primary breast carcinoma, we observed relatively abundant expression of Tetherin, a cell ...
Aejaz Sayeed   +5 more
doaj   +1 more source

BST2/Tetherin enhances HCMV entry into fibroblasts.

open access: yes, 2013
A) Relative viral genome copies were quantified using Taqman probes in the BST2-expressing or control THFs exposed to HCMV AD169 (MOI = 2) at 37°C for 90 min followed by a citric acid (pH = 3) wash.
Mandana Mansouri (340371)   +5 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

Characterization of the BST2/Tetherin cytoplasmic tail and understanding BST2-mediated NF-κB activation [PDF]

open access: yes, 2017
BST2/Tetherin is an interferon-induced anti-viral host protein that restricts the release of newly assembled virions of enveloped viruses at the plasma membrane (PM) of infected cells.
Rizk, Maryan
core  

BST2 binds and effectively activates ILT7.

open access: yes, 2015
(A-E) BST2 binds ILT7. (A) Purified GST-BST2 and bacILT7 were analyzed by SDS-PAGE and visualized by Coomassie brilliant blue staining. (B) Recombinant GST-BST2 pre-coated on the surface of Biacore sensor chips, was mixed with the indicated ...
Mariana G. Bego (107768)   +5 more
core   +1 more source

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

open access: yesAnimal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren   +6 more
wiley   +1 more source

HIV-1 Adapts To Replicate in Cells Expressing Common Marmoset APOBEC3G and BST2 [PDF]

open access: yesJournal of Virology, 2016
ABSTRACT Previous studies have shown that a major block to HIV-1 replication in common marmosets operates at the level of viral entry and that this block can be overcome by adaptation of the virus in tissue-cultured cells. However, our current studies indicate that HIV-1 encounters additional postentry blocks in common marmoset ...
Fernández-Oliva, Alberto   +5 more
openaire   +3 more sources

Antagonism of BST2/Tetherin, a new restriction factor of respiratory syncytial virus, requires the viral NS1 protein.

open access: yesPLoS Pathogens
Human respiratory syncytial virus (RSV) is an enveloped RNA virus and the leading viral agent responsible for severe pediatric respiratory infections worldwide.
Katherine Marougka   +7 more
doaj   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

open access: yesArthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy