Results 31 to 40 of about 8,611 (185)

Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis

Frontiers in Immunology, 2023
BackgroundEndometriosis (EM) is a benign, multifactorial, immune-mediated inflammatory disease that is characterized by persistent activation of the NF‐κB signaling pathway and some features of malignancies, such as proliferation and lymphangiogenesis ...
Jixin Li, Yanan He, Yanjun Qu, Chengcheng Ren, Xiaotong Wang, Yan Cheng, Liyuan Sun, Xin Zhang, Guangmei Zhang   +8 more
doaj   +1 more source

BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer [PDF]

Cell Death & Disease, 2017
AbstractConcurrent/adjuvant cisplatin-based chemoradiotherapy is regarded as the standard of treatment for locoregionally advanced nasopharyngeal carcinoma (NPC). However, patients who do not respond to cisplatin suffer, rather than benefit, from chemotherapy treatment.
Kuang, Chun-mei, Fu, Xiang, Hua, Yi-jun, Shuai, Wen-di, Ye, Zhi-hua, Li, Yingchang, Peng, Qi-hua, Li, Yi-zhuo, Chen, Shuai, Qian, Chao-nan, Huang, Wenlin, Liu, Ran-yi   +11 more
openaire   +2 more sources

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity [PDF]

, 2015
The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear.
Abudureyimu, A, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +4 more
core   +2 more sources

Evaluating predictive markers for viral rebound and safety assessment in blood and lumbar fluid during HIV-1 treatment interruption [PDF]

, 2020
Background: Validated biomarkers to evaluate HIV-1 cure strategies are currently lacking, therefore requiring analytical treatment interruption (ATI) in study participants.
De Langhe, Nele, De Scheerder, Marie-Angélique, Fuchs, Dietmar, Gisslén, Magnus, Lemey, Philippe, Noppe, Ytse, Palmer, Sarah, Pelgrom, Jolanda, Rutsaert, Sofie, Trypsteen, Wim, Van Der Gucht, Beatrijs, Van Hecke, Clarissa, Van Wanzeele, Filip, Vandekerckhove, Linos, Vrancken, Bram, Zetterberg, Henrik   +15 more
core   +1 more source

BST2 Mediates Osteoblast Differentiation via the BMP2 Signaling Pathway in Human Alveolar-Derived Bone Marrow Stromal Cells.

PLoS ONE, 2016
The molecular mechanisms controlling the differentiation of bone marrow stromal stem cells into osteoblasts remain largely unknown. In this study, we investigated whether bone marrow stromal antigen 2 (BST2) influences differentiation toward the ...
Su-Hyang Yoo, Jae Goo Kim, Beom-Su Kim, Jun Lee, Sung-Hee Pi, Hyun-Dae Lim, Hong-In Shin, Eui-Sic Cho, Hyung-Keun You   +8 more
doaj   +1 more source

BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer

International Journal of Biological Sciences, 2023
Background: Tumor-associated macrophages (TAMs) are one of the most prominent tumor-infiltrating immune cells in the tumor microenvironment (TME) of CRC and play a vital role in the progression of CRC. BST2 was predicted to be associated with the infiltration of TAMs.
He, Xuefeng, Chen, Huaijun, Zhong, Xinyang, Wang, Yaxian, Hu, Zijuan, Huang, Huixia, Zhao, Senlin, Wei, Ping, Shi, Debing, Li, Dawei   +9 more
openaire   +2 more sources

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]

, 2015
Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A, Anstaett, O L, Brownlie, J, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +6 more
core   +2 more sources

BST2 facilitates activation of hematopoietic stem cells through ERK signaling. [PDF]

Exp Hematol
The proinflammatory cytokine interferon gamma (IFNγ) is upregulated in a variety of infections and contributes to bone marrow failure through hematopoietic stem cell (HSC) activation and subsequent exhaustion. The cell-surface protein, bone marrow stromal antigen 2 (BST2), is a key mediator of this process, because it is induced upon IFN stimulation ...
Florez MA, Thatavarty A, Le DT, Hill HA, Jeong Y, Ho BM, Kus P, Wathan TK, Kain BN, Huang S, Park D, King KY.   +11 more
europepmc   +3 more sources

Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection. [PDF]

, 2013
A majority of individuals infected with human immunodeficiency virus (HIV) have inadequate access to antiretroviral therapy and ultimately develop debilitating oral infections that often correlate with disease progression.
A Uehara, Aftab A. Ansari, Angeline T. Dang, AR Thurman, AT Dang, BA Dale, BL Shacklett, BP Gomes, Bruce J. Paster, C Beaurepaire, C Gervasoni, C Heise, Chin-Shang Li, Christina Murphy, D Preza, DA Reznik, DR Dixon, E Elinav, E Zaura, F Meurens, FE Dewhirst, G Diamond, G Diamond, G Xie, H Wang, H Yang, HT Rupniak, I Viard-Leveugle, J Benes, J Mitchell, JA Aas, JA Aas, JC Leao, JE Hull, JE Meyer, JM Garcia-Lechuz, JT Arotiba, L Feller, M Bando, M Bruewer, M Guadalupe, M Mittal, M Raffatellu, MD George, MD George, MD George, MH Shaw, Michael D. George, MP George, MT Pollanen, Niku Borujerdpur, P Regenhard, R Saini, RM Zakir, Ross Tarara, RS Veazey, S Chotai, S Gennaro, S Sugawara, Satya Dandekar, Sumathi Sankaran-Walters, Susan Ocon, T Chen, TG Shrihari, W Hartzell, Z Smit-McBride   +65 more
core   +3 more sources

Control of BST2 by NOD2.

, 2023
We provide evidence here from loss-of-function studies in mice and gain-of-function studies in human cells (1, 2) which demonstrate control of bone marrow stromal cell antigen 2, BST2, by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2.
openaire   +1 more source