Results 11 to 20 of about 6,331 (185)
BST2/Tetherin enhances entry of human cytomegalovirus.
PLoS Pathogens, 2011 Interferon-induced BST2/Tetherin prevents budding of vpu-deficient HIV-1 by tethering mature viral particles to the plasma membrane. BST2 also inhibits release of other enveloped viruses including Ebola virus and Kaposi's sarcoma associated herpesvirus ...
Kasinath Viswanathan +5 more
doaj +4 more sources
Vpu and BST2: still not there yet? [PDF]
Frontiers in Microbiology, 2012 Extensive investigations have identified two cellular proteins in humans that potently inhibit HIV-1 replication and are widely accepted as ‘restriction factors’.
Kei eSato +3 more
doaj +5 more sources
Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin [PDF]
ChemistryOpen, 2021 We present in this work a first X‐ray Absorption Spectroscopy study of the interactions of Zn with human BST2/tetherin and SARS‐CoV‐2 orf7a proteins as well as with some of their complexes.
Dr. Maria Petrosino +8 more
doaj +9 more sources
Identification of BST2 Contributing to the Development of Glioblastoma Based on Bioinformatics Analysis [PDF]
Frontiers in Genetics, 2022 Rigorous molecular analysis of the immune cell environment and immune response of human tumors has led to immune checkpoint inhibitors as one of the most promising strategies for the treatment of human cancer.
Yang Kong +19 more
doaj +6 more sources
BST2/Tetherin Inhibition of Alphavirus Exit [PDF]
Viruses, 2015 Alphaviruses such as chikungunya virus (CHIKV) and Semliki Forest virus (SFV) are small enveloped RNA viruses that bud from the plasma membrane. Tetherin/BST2 is an interferon-induced host membrane protein that inhibits the release of many enveloped ...
Yaw Shin Ooi +2 more
exaly +5 more sources
BST2/tetherin inhibits dengue virus release from human hepatoma cells.
PLoS ONE, 2012 UnlabelledType I interferons (IFN) have been shown to play an important role for inhibiting Dengue virus (DENV) infection. Identifying IFN-induced cellular proteins are essential for understanding its mechanisms against DENV.
Xiao-Ben Pan +3 more
doaj +4 more sources
Identification of BST2 as a conjunctival epithelial stem/progenitor cell marker
iScience, 2023 Summary: The conjunctival epithelium consists of conjunctival epithelial cells and goblet cells derived from conjunctival epithelial stem/progenitor cells.
Masahiro Kitao +8 more
doaj +3 more sources
Journal of Immunology Research, 2021 Accumulating evidence has elucidated the biological function of lncRNAs in various tumors. FGD5 antisense RNA 1 (FGD5-AS1) is identified as a significant tumor regulator in malignancies. Up to now, the detailed function of FGD5-AS1 in cervical cancer and
Guokun Liu +4 more
doaj +2 more sources
, 2023 We provide evidence here from loss-of-function studies in mice and gain-of-function studies in human cells (1, 2) which demonstrate control of bone marrow stromal cell antigen 2, BST2, by the NLR (nucleotide-binding oligomerization domain-like receptor ...
Shahan Mamoor
core +2 more sources
Frontiers in Immunology, 2023 BackgroundEndometriosis (EM) is a benign, multifactorial, immune-mediated inflammatory disease that is characterized by persistent activation of the NF‐κB signaling pathway and some features of malignancies, such as proliferation and lymphangiogenesis ...
Jixin Li +8 more
doaj +3 more sources