Results 71 to 80 of about 6,331 (185)

Use of the “Ru‐1O2‐Hydrazide” System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells

Advanced Science, Volume 13, Issue 52, 18 September 2026.
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun, Kaihong Wang, Haifu Sun, Kemei Tao, Xiang Li, Xiuhua Zhao, Shuang Qiu   +6 more
wiley   +1 more source

BST2 immunolocalization in primary invasive breast cancer.

, 2013
The association between BST2 positive status and histological grade is significant ...
Zhenhang Meng (424445), Aejaz Sayeed (220486), Gloria Luciani-Torres (424444), James L. Bennington (424446), Shanaz H. Dairkee (167120), Dan H. Moore (424447)   +5 more
core   +1 more source

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi, Hanlou Yang, Junting Huang, Pengfei Wu, Shiying Zhou, Zunde Liao, Min Han, Zishan Chen, Xiaoyu Huang, Nan Ma, Jie Zhou, Mingqiang Li, Yiling Zhong   +12 more
wiley   +1 more source

BST2 inhibits SARS-CoV-2 virion release but the virus downregulates BST2.

(A) A549-ACE2 cells were not infected (untreated), infected with lentiviral-like particles (mock), or infected with SARS-CoV-2 HK at MOI = 1. Six hours later, the mRNA levels of BST2 were measured by RT-qPCR.
Sydney Simpson (5132285), Ruth Serra-Moreno (66346), Jared Benjamin (11621560), Yuexuan Chen (11424022), Haley Aull (17756318), Yuhang Shi (8491302)   +5 more
core   +1 more source

BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer [PDF]

Cell Death & Disease, 2017
AbstractConcurrent/adjuvant cisplatin-based chemoradiotherapy is regarded as the standard of treatment for locoregionally advanced nasopharyngeal carcinoma (NPC). However, patients who do not respond to cisplatin suffer, rather than benefit, from chemotherapy treatment.
Kuang, Chun-mei, Fu, Xiang, Hua, Yi-jun, Shuai, Wen-di, Ye, Zhi-hua, Li, Yingchang, Peng, Qi-hua, Li, Yi-zhuo, Chen, Shuai, Qian, Chao-nan, Huang, Wenlin, Liu, Ran-yi   +11 more
openaire   +2 more sources

IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

Cell Reports
Summary: Pancreatic ductal adenocarcinoma (PDAC) features an immunosuppressive tumor microenvironment (TME) that resists immunotherapy. Tumor-associated macrophages, abundant in the TME, modulate T cell responses.
Chenlei Zheng, Junli Wang, Yu Zhou, Yi Duan, Rujia Zheng, Yuting Xie, Xiaobao Wei, Jiangchao Wu, Hang Shen, Mao Ye, Bo Kong, Yun-Hua Liu, Pinglong Xu, Qi Zhang, Tingbo Liang   +14 more
doaj   +1 more source

Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressorsResearch in context

EBioMedicine, 2019
Background: A wide range of host restriction factors (RF) become upregulated upon HIV-1 infection to suppress viral infectivity and may aid viremic control in vivo.
Clarissa Van Hecke, Wim Trypsteen, Eva Malatinkova, Ward De Spiegelaere, Karen Vervisch, Sofie Rutsaert, Sabine Kinloch-de Loes, Magdalena Sips, Linos Vandekerckhove   +8 more
doaj   +1 more source

Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2

Cell Death Discovery, 2021
Mesenchymal stem cells (MSCs) show significant therapeutic effects in type 1 diabetes mellitus (T1DM) as regulating the inflammatory processes. However, little is known about the detailed process of MSCs immunosuppression in T1DM.
Na Zhou, Weijiang Liu, Wei Zhang, Yuanlin Liu, Xue Li, Yang Wang, Rongxiu Zheng, Yi Zhang   +7 more
doaj   +1 more source

Neurobiological mechanisms of 40‐Hz stimulation in Alzheimer's disease: evidence, heterogeneity, and constraints

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract Early disruption of gamma oscillations is increasingly recognized as a contributor to neurodegeneration and cognitive decline in Alzheimer's disease (AD), positioning 40‐Hz stimulation as a promising neuromodulatory strategy. However, its neurophysiological and cognitive effects remain highly variable across studies, underscoring the need for ...
Lin Qi, Weiye Wang, Reema Abdullah, Yilei Zhao, Zhibin Wang, Yi Tang, Benyan Luo, Guoping Peng   +7 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1673-1685, August 2026.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source