The Development of Eletriptan Hydrobromide Immediate Release Buccal Films Using Central Composite Rotatable Design: An In Vivo and In Vitro Approach. [PDF]
Polymers (Basel), 2022 The objective is to develop immediate release buccal films of Eletriptan Hydrobromide (EHBR) using hydroxypropyl methylcellulose (HPMC) E5. The buccal films have the ability to disintegrate rapidly and provide both systemic and local effects. The solvent
Siddique W +9 more
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Physicochemical Properties of Pineapple Stem Fiber/Gellan Gum Biocomposite Films as a Potential Platform for Buccal Drug Delivery [PDF]
Journal of Functional BiomaterialsThe physicochemical properties of buccal films are vital for evaluating their suitability for mucosal applications. By focusing on these properties, researchers can enhance the mechanical functionality and mucoadhesion of the films.
Tuty Fareyhynn Mohammed Fitri +4 more
doaj +2 more sources
Mucoadhesive buccal films of tramadol for effective pain management
Revista Brasileira de AnestesiologiaBackground and objectives: Tramadol hydrochloride is a centrally-acting synthetic opioid analgesic binding to specific opioid receptors. It is used in the management of chronic pain and is recommended as first line drug in the treatment of postoperative ...
Xiao-Qin Li +6 more
doaj +2 more sources
Preparation of orally disintegrated membranes from liquorice inclusion complexes [PDF]
BIO Web of Conferences, 2023 Objective: to prepare and evaluate orally disintegrating films of liquorice inclusion complexes. Methods: the active components of Chinese liquorice were extracted by pressurised extraction technique, and the inclusion complexes were prepared by ...
Chen Lei +5 more
doaj +1 more source
Development of polymer-bound fast-dissolving metformin buccal film with disintegrants
International Journal of Nanomedicine, 2015 Shaikh Ershadul Haque, Angappan Sheela Materials Chemistry Division, Centre for Nanomaterials, School of Advanced Sciences, VIT University, Vellore, India Abstract: Fast-dissolving drug-delivery systems are considered advantageous over the existing ...
Haque SE, Sheela A
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Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation
Pharmaceutics, 2021 The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low oral bioavailability and extensive first pass metabolism. The purpose of this investigation was to optimize the thin mucoadhesive buccal film of rizatriptan and
Anroop B. Nair +6 more
doaj +1 more source
An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
doaj +1 more source
Buccal films of prednisolone with enhanced bioavailability [PDF]
Drug Delivery, 2014 The conventional formulation of prednisolone is considered to be low in efficacy, primarily on account of their failure in providing and maintaining effective therapeutic drug levels. This study aims to focus on development of a mucoadhesive buccal delivery system with a twofold objective of offering a rapid as well as a prolonged delivery of ...
Rachna, Kumria +3 more
openaire +2 more sources
Applied Sciences, 2021 Background: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health and wellbeing.
Patrícia Batista +4 more
doaj +1 more source
Evaluation of Monolayer and Bilayer Buccal Films Containing Metoclopramide. [PDF]
PharmaceuticsThe objective of this study was to develop buccal film formulations containing metoclopramide hydrochloride monohydrate (MCP) with and without a backing layer and to evaluate their release properties and physiochemical stability. The crystallization of MCP in the polymer matrix was monitored with image analysis techniques for rapid and scalable ...
Grilc B, Planinšek O.
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