Results 171 to 180 of about 8,546 (246)

VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channels. [PDF]

PNAS Nexus
Kolski-Andreaco A, Balut CM, Green MD, Sembrat J, Bridges RJ, Singh AK, Tse C, Butterworth MB, Devor DC.   +8 more
europepmc   +1 more source

Neuronal swelling implicated in functional recovery after spinal cord injury. [PDF]

Neural Regen Res
Li Q.
europepmc   +1 more source

When the gatekeeper falls: developmental vulnerability of the thalamic reticular nucleus in neonatal and pediatric hypoxic-ischemic brain injury. [PDF]

Front Syst Neurosci
Hsiao K.
europepmc   +1 more source

Combined use of Bumetanide and MGE cell transplantation alleviates neuropathic pain and its mechanism after spinal cord injury in mice. [PDF]

Front Immunol
Yu Y, Wang F.
europepmc   +1 more source

Sodium Bumetanide Trihydrate

Acta Crystallographica Section C Crystal Structure Communications, 1995
The structure of sodium 3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoate trihydrate (sodium bumetanide trihydrate), Na + .C 17 H 19 N 2 O 5 S - .3H 2 O, consists of a layer of sodium ions and water molecules between two layers of bumetanide molecules.
SAVIANO M, FATTORUSSO, Roberto, LOMBARDI A, ZACCARO L, PEDONE C.   +4 more
openaire   +5 more sources

Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain

Neuropharmacology, 2017
There is accumulating evidence that bumetanide, which has been used over decades as a potent loop diuretic, also exerts effects on brain disorders, including autism, neonatal seizures, and epilepsy, which are not related to its effects on the kidney but ...
Kerstin Römermann, Maren Fedrowitz, Philip Hampel   +2 more
exaly   +4 more sources