Results 1 to 10 of about 3,430 (160)

Two Human Cases of Fatal Meningoencephalitis Associated with Potosi and Lone Star Virus Infections, United States, 2020-2023. [PDF]

Emerg Infect Dis
We used clinical metagenomic next-generation sequencing of cerebrospinal fluid to investigate bunyavirus infections in 2 immunocompromised patients in the United States who had fatal meningoencephalitis.
Chiu CY, Godasi RR, Hughes HR, Servellita V, Foresythe K, Tubati A, Zorn K, Sidhu S, Wilson MR, Bethina SV, Abenroth D, Cheng Y, Grams R, Reese C, Isada C, Thottempudi N.   +15 more
europepmc   +2 more sources

Suppression of Interferon Response and Antiviral Strategies of Bunyaviruses. [PDF]

Trop Med Infect Dis
The order Bunyavirales belongs to the class of Ellioviricetes and is classified into fourteen families. Some species of the order Bunyavirales pose potential threats to human health.
He Y, Shen M, Wang X, Yin A, Liu B, Zhu J, Zhang Z.   +6 more
europepmc   +2 more sources

The mechanism of genome replication and transcription in bunyaviruses

PLoS Pathogens, 2023
Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority diseases requiring urgent development of medical countermeasures highlighting
Hélène Malet, Harry M. Williams, Stephen Cusack, Maria Rosenthal   +3 more
doaj   +2 more sources

Visualizing the ribonucleoprotein content of single bunyavirus virions reveals more efficient genome packaging in the arthropod host

Communications Biology, 2021
Bermúdez-Méndez et al. describe a FISH-immunofluorescence method that allows simultaneous visualization of bunyavirus genome segments and virions at single-molecule resolution.
Erick Bermúdez-Méndez, Eugene A. Katrukha, Cindy M. Spruit, Jeroen Kortekaas, Paul J. Wichgers Schreur   +4 more
doaj   +1 more source

Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice

mBio, 2021
Oropouche virus (OROV) infection of humans is associated with a debilitating febrile illness that can progress to meningitis or encephalitis. First isolated from a forest worker in Trinidad and Tobago in 1955, the arbovirus OROV has since been detected ...
Sarah Hulsey Stubbs, Marjorie Cornejo Pontelli, Nischay Mishra, Changhong Zhou, Juliano de Paula Souza, Rosa Maria Mendes Viana, W. Ian Lipkin, David M. Knipe, Eurico Arruda, Sean P. J. Whelan   +9 more
doaj   +1 more source

Immunological Responses to Seoul Orthohantavirus in Experimentally and Naturally Infected Brown Rats (Rattus norvegicus)

Viruses, 2021
To clarify the mechanism of Seoul orthohantavirus (SEOV) persistence, we compared the humoral and cell-mediated immune responses to SEOV in experimentally and naturally infected brown rats.
Shumpei P. Yasuda, Kenta Shimizu, Takaaki Koma, Nguyen Thuy Hoa, Mai Quynh Le, Zhuoxing Wei, Devinda S. Muthusinghe, Sithumini M. W. Lokupathirage, Futoshi Hasebe, Tetsu Yamashiro, Jiro Arikawa, Kumiko Yoshimatsu   +11 more
doaj   +1 more source

Development of Rice Stripe Tenuivirus Minireplicon Reverse Genetics Systems Suitable for Analyses of Viral Replication and Intercellular Movement

Frontiers in Microbiology, 2021
Rice stripe virus (RSV), a tenuivirus with four negative-sense/ambisense genome segments, is one of the most devastating viral pathogens affecting rice production in many Asian countries.
Xiaoyan Zhang, Kai Sun, Yan Liang, Shuo Wang, Kaili Wu, Zhenghe Li, Zhenghe Li, Zhenghe Li   +7 more
doaj   +1 more source

An Overview of the Infectious Cycle of Bunyaviruses

Viruses, 2022
Bunyaviruses represent the largest group of RNA viruses and are the causative agent of a variety of febrile and hemorrhagic illnesses. Originally characterized as a single serotype in Africa, the number of described bunyaviruses now exceeds over 500 ...
Hani Boshra
doaj   +1 more source

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

eLife, 2023
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe   +21 more
doaj   +1 more source

A rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis

Journal of Infection in Developing Countries, 2016
Herein we describe a rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis (HLH) in a 62-year-old female patient. The novel bunyavirus infects patients with or without HLH who have similar clinical features such as fever ...
Ling Lin, You-Zu Xu, Xiao-Mai Wu, Hong-Fei Ge, Jia-Xi Feng, Mei-Fang Chen, Dong-Qing Lv, Bo-Li Li, Jian Lin   +8 more
doaj   +1 more source