Results 71 to 80 of about 3,430 (160)

Crimean-Congo Hemorrhagic Fever Virus for Clinicians—Epidemiology, Clinical Manifestations, and Prevention

open access: yesEmerging Infectious Diseases
Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate
Maria G. Frank   +2 more
doaj   +1 more source

RNA Encapsidation and Packaging in the Phleboviruses

open access: yesViruses, 2016
The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Katherine E. Hornak   +2 more
doaj   +1 more source

Tamdy virus pathogenesis in immunocompetent and immunocompromised mouse models

open access: yesVirulence
Tamdy virus (TAMV) is one of the zoonotic tick-borne bunyaviruses that have emerged as global public health threats in recent decades. To date, however, TAMV pathogenesis remains poorly understood.
Mingxue Cui   +8 more
doaj   +1 more source

Rift Valley fever virus activates multiple cell death pathways in neurons

open access: yesJournal of Virology
Neuronal injury and death contribute to long-term impairments and lethality during viral encephalitis. Rift Valley fever virus (RVFV), an arbovirus with epidemic potential, can manifest as late-onset encephalitis in humans, yet this disease outcome ...
Kaleigh A. Connors   +7 more
doaj   +1 more source

Non-Structural Proteins of Arthropod-Borne Bunyaviruses: Roles and Functions

open access: yesViruses, 2013
Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl   +4 more
doaj   +1 more source

Development of FRET-based cap-snatching endonuclease assay

open access: yesMicrobiology Spectrum
The order Bunyavirales consists of over 300 species of segmented, negative-strand RNA viruses. These viruses have a tri-segmented genome (S, M, and L segments) that encodes the nucleocapsid protein (N protein), glycoprotein precursor, and RNA-dependent ...
Jeeva Subbiah   +3 more
doaj   +1 more source

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

open access: yesmBio, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU)
Florine E. M. Scholte   +10 more
doaj   +1 more source

Three-Segment RNA Genome of Lumbo Virus (Bunyavirus)

open access: yesIntervirology, 1973
The sedimentation analysis and polyacrylamide gel electrophoresis of RNA extracted from Lumbo and Tahyna viruses, which belong to the California group of the Bunyamwera supergroup of arboviruses ...
M, Bouloy   +3 more
openaire   +2 more sources

Spatiotemporal Analysis of Guaroa Virus Diversity, Evolution, and Spread in South America

open access: yesEmerging Infectious Diseases, 2015
We conducted phylogeographic modeling to determine the introduction and spread of Guaroa virus in South America. The results suggest a recent introduction of this virus into regions of Peru and Bolivia over the past 60–70 years and emphasize the need for
Allison Groseth   +8 more
doaj   +1 more source

A highly pathogenic new bunyavirus emerged in China

open access: yesEmerging Microbes & Infections, 2013
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that was discovered in China in 2010. The causative agent has been identified as a new member of the Phlebovirus genus in the family Bunyaviridae and has been designated severe fever with thrombocytopenia virus (SFTSV).
openaire   +2 more sources

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