Interscalene nerve block with plain bupivacaine versus liposomal bupivacaine for arthroscopic rotator cuff repair: A randomized controlled trial. [PDF]
Saudi J AnaesthBackground: Although single injections with anesthetics are commonly administered given their safety, their short-acting nature limits pain control.
Lee PS +8 more
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Comparison of pain with bupivacaine and bupivacaine-sufentanil combination in women undergoing cesarean section with spinal anesthesia: A double-blind randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022 Introduction: Today, spinal anesthesia is the method of choice for most cesarean sections. Postoperative pain control has always been one of the main concerns of anesthesiologists.
Hasan Zabetian +3 more
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Comparison of addition of fentanyl or clonidine to Intrathecal bupivacaine versus Intrathecal bupivacaine alone for lower limb surgeries in elderly patients: A prospective, randomised study: Intrathecal fentanyl/clonidine ± bupivacaine for surgery in elderly [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2023 Orthopaedic long bone fracture surgeries in elderly patients have their own inherent risks during anaesthesia. We aimed to compare the effect of adding clonidine or fentanyl to low dose intrathecal bupivacaine as opposed to intrathecal bupivacaine alone.
Bhat Pai Rohini V. +5 more
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Frontiers in Oncology, 2021 Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti-tumor activity.
Jian-Hua Gu +6 more
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Real-World Pharmacovigilance Analysis of Adverse Events Associated with Liposomal Bupivacaine and Bupivacaine. [PDF]
J Pain ResDong Xu Chen,1,2,* Xuan Ming Chen,3,* Shou Ming Chen,1,2 Yi Da Wang3 1Department of Anesthesiology, West China Second Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Key Laboratory of Birth Defects and Related Diseases of ...
Chen DX, Chen XM, Chen SM, Wang YD.
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BMC Pharmacology and Toxicology, 2021 Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant ...
Hongfei Chen +3 more
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The effect of adjuvant midazolam compared with fentanyl on the duration of spinal anesthesia with 0.5% bupivacaine in opium abusers [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundThere are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine
Farhad Safari +2 more
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Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum
Journal of Anaesthesiology Clinical Pharmacology, 2023 Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi +6 more
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Advances in Pharmacological and Pharmaceutical Sciences, 2020 Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer +5 more
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Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]
PLoS ONE, 2018 In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li +11 more
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