Local anaesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro [PDF]
Scientific Reports, 2016 Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L +5 more
core +9 more sources
Analgesia Quality and Duration of Fentanyl and Sufentanil Added to Bupivacaine in Spinal Anesthesia in Inguinal Hernia Surgery: A Double‐Blind Parallel Randomized Controlled Trial [PDF]
Health Science ReportsBackground and Aims To compare the quality and duration of analgesia provided by Fentanyl and Sufentanil when added to 12–15 mg Bupivacaine 0.5% in spinal anesthesia for inguinal hernia surgery.
Haniyeh Soleimany +3 more
doaj +2 more sources
Liposomal Bupivacaine vs. Plain Bupivacaine with Dexamethasone for Rhomboid Intercostal Block in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery: A Randomized Non-inferiority Trial [PDF]
Pain and TherapyIntroduction Effective and sustained postoperative analgesia is essential to enhance recovery after video-assisted thoracoscopic surgery (VATS). Liposomal bupivacaine, a multivesicular formulation enabling extended local anesthetic release, offers a ...
Lei Xie +7 more
doaj +2 more sources
COMPARISON OF BUPIVACAINE AND BUPIVACAINE WITH FENTANYL IN CONTINUOUS EXTRADURAL ANALGESIA DURING LABOUR [PDF]
British Journal of Anaesthesia, 1989 In a randomized, double-blind study of 39 mothers in labour, we have compared a loading dose of 0.5% bupivacaine 6.0 ml and fentanyl 100 micrograms given extradurally, followed by an infusion of 0.08% bupivacaine 15 ml h-1 plus fentanyl 37.5 micrograms h-1, with a loading dose of 0.5% bupivacaine 6.0 ml and saline 2.0 ml, followed by an extradural ...
Gregory C. Jones +3 more
openalex +6 more sources
iTRAQ proteomics analysis reveals that PI3K is highly associated with bupivacaine-induced neurotoxicity pathways [PDF]
Proteomics, 2016 Bupivacaine, a commonly used local anesthetic, has potential neurotoxicity through diverse signaling pathways. However, the key mechanism of bupivacaine-induced neurotoxicity remains unclear.
Jiang, S +9 more
core +2 more sources
Comparison of pain with bupivacaine and bupivacaine-sufentanil combination in women undergoing cesarean section with spinal anesthesia: A double-blind randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022 Introduction: Today, spinal anesthesia is the method of choice for most cesarean sections. Postoperative pain control has always been one of the main concerns of anesthesiologists.
Hasan Zabetian +3 more
doaj +1 more source
Bioengineered, 2022 The study aimed to explore the effects of local anesthetic bupivacaine on bladder cancer cells in vivo and in vitro. The cytotoxicity was detected by MTT assay. Apoptosis was measured by Hoechst 33342 staining and TUNEL.
Jianli Hao, Weiqing Zhang, Zeqing Huang
semanticscholar +1 more source
JAMA Surgery, 2022 This randomized clinical trial assesses the efficacy and cost-effectiveness of liposomal bupivacaine plus bupivacaine hydrochloride compared with bupivacaine hydrochloride alone for postoperative recovery and pain management among patients undergoing ...
T. Hamilton +17 more
semanticscholar +1 more source
Frontiers in Oncology, 2021 Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti-tumor activity.
Jian-Hua Gu +6 more
doaj +1 more source