Results 11 to 20 of about 74,417 (287)

Optimal Analgesic Volume for Popliteal Plexus Block After Total Knee Arthroplasty: A Blinded RCT Protocol. [PDF]

open access: yesActa Anaesthesiol Scand
ABSTRACT Background Adjunct treatment with a popliteal plexus block (PPB) provides moderate enhancement to multimodal analgesic regimens following total knee arthroplasty while maintaining motor function. However, the optimal anesthetic volume of local anesthetic for PPB remains unknown.
Sørensen JK   +4 more
europepmc   +2 more sources

Bupivacaine Liposomal versus Bupivacaine: Comparative Review [PDF]

open access: yesHospital Pharmacy, 2014
Bupivacaine liposomal injection was recently approved by the US Food and Drug Administration (FDA) as a local anesthetic for use in management of postsurgical pain in adults. When compared to placebo, bupivacaine liposomal decreases postoperative pain and opioid use.
Noviasky, John   +4 more
openaire   +3 more sources

The effect of adjuvant midazolam compared with fentanyl on the duration of spinal anesthesia with 0.5% bupivacaine in opium abusers [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundThere are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine
Farhad Safari   +2 more
doaj   +1 more source

Perineural Liposomal Bupivacaine Is Not Superior to Nonliposomal Bupivacaine for Peripheral Nerve Block Analgesia.

open access: yesAnesthesiology, 2020
BACKGROUND Liposomal bupivacaine is purported to extend analgesia of peripheral nerve blocks when administered perineurally. However, evidence of the clinical effectiveness of perineural liposomal bupivacaine is mixed.
N. Hussain   +6 more
semanticscholar   +1 more source

Clinical Effectiveness of Liposomal Bupivacaine Administered by Infiltration or Peripheral Nerve Block to Treat Postoperative Pain.

open access: yesAnesthesiology, 2020
The authors provide a comprehensive summary of all randomized, controlled trials (n = 76) involving the clinical administration of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, USA) to control postoperative pain that are currently published ...
B. Ilfeld, J. Eisenach, R. Gabriel
semanticscholar   +1 more source

Transversus Abdominis Plane Block With Liposomal Bupivacaine for Pain After Cesarean Delivery in a Multicenter, Randomized, Double-Blind, Controlled Trial

open access: yesAnesthesia and Analgesia, 2020
BACKGROUND: In women undergoing cesarean delivery under spinal anesthesia with intrathecal morphine, transversus abdominis plane (TAP) block with bupivacaine hydrochloride (HCl) may not improve postsurgical analgesia.
S. Nedeljkovic   +11 more
semanticscholar   +1 more source

Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation

open access: yesAnesthesiology, 2020
Background: Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable
E. Schwenk   +13 more
semanticscholar   +1 more source

Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2020
Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer   +5 more
doaj   +1 more source

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]

open access: yesPLoS ONE, 2018
In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li   +11 more
doaj   +1 more source

Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi   +6 more
doaj   +1 more source

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