Results 11 to 20 of about 76,850 (268)

Perineural Liposomal Bupivacaine Is Not Superior to Nonliposomal Bupivacaine for Peripheral Nerve Block Analgesia.

open access: yesAnesthesiology, 2020
BACKGROUND Liposomal bupivacaine is purported to extend analgesia of peripheral nerve blocks when administered perineurally. However, evidence of the clinical effectiveness of perineural liposomal bupivacaine is mixed.
N. Hussain   +6 more
semanticscholar   +1 more source

Clinical Effectiveness of Liposomal Bupivacaine Administered by Infiltration or Peripheral Nerve Block to Treat Postoperative Pain.

open access: yesAnesthesiology, 2020
The authors provide a comprehensive summary of all randomized, controlled trials (n = 76) involving the clinical administration of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, USA) to control postoperative pain that are currently published ...
B. Ilfeld, J. Eisenach, R. Gabriel
semanticscholar   +1 more source

Incisional infiltration versus transversus abdominis plane block of liposomal bupivacaine after midline vertical laparotomy for suspected gynecologic malignancy: a pilot study

open access: yesGynecologic Oncology Reports, 2023
Background: To evaluate whether incisional infiltration of liposomal bupivacaine would decrease opioid requirement and pain scores after midline vertical laparotomy for suspected or known gynecologic malignancy compared with transversus abdominis plane ...
Ashley S. Moon   +7 more
doaj   +1 more source

Transversus Abdominis Plane Block With Liposomal Bupivacaine for Pain After Cesarean Delivery in a Multicenter, Randomized, Double-Blind, Controlled Trial

open access: yesAnesthesia and Analgesia, 2020
BACKGROUND: In women undergoing cesarean delivery under spinal anesthesia with intrathecal morphine, transversus abdominis plane (TAP) block with bupivacaine hydrochloride (HCl) may not improve postsurgical analgesia.
S. Nedeljkovic   +11 more
semanticscholar   +1 more source

Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2020
Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer   +5 more
doaj   +1 more source

Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation

open access: yesAnesthesiology, 2020
Background: Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable
E. Schwenk   +13 more
semanticscholar   +1 more source

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]

open access: yesPLoS ONE, 2018
In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li   +11 more
doaj   +1 more source

Dexamethasone versus neostigmine as an adjuvant to bupivacaine 0.25% for caudal analgesia in children undergoing open inguinal hernia repair

open access: yesEgyptian Journal of Anaesthesia, 2017
Background: Co-administration of dexamethasone or neostigmine with local anesthetic solution for caudal block (CB) can prolong postoperative analgesia duration.
Mohamed M. Abu Elyazed, Gehan M. Eid
doaj   +1 more source

Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi   +6 more
doaj   +1 more source

Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta

open access: yesAnesthesiology Research and Practice, 2010
Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods.
Mai Mukozawa, Ko Takakura, Maki Mizogami
doaj   +1 more source

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