Results 11 to 20 of about 76,850 (268)
BACKGROUND Liposomal bupivacaine is purported to extend analgesia of peripheral nerve blocks when administered perineurally. However, evidence of the clinical effectiveness of perineural liposomal bupivacaine is mixed.
N. Hussain +6 more
semanticscholar +1 more source
The authors provide a comprehensive summary of all randomized, controlled trials (n = 76) involving the clinical administration of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, USA) to control postoperative pain that are currently published ...
B. Ilfeld, J. Eisenach, R. Gabriel
semanticscholar +1 more source
Background: To evaluate whether incisional infiltration of liposomal bupivacaine would decrease opioid requirement and pain scores after midline vertical laparotomy for suspected or known gynecologic malignancy compared with transversus abdominis plane ...
Ashley S. Moon +7 more
doaj +1 more source
BACKGROUND: In women undergoing cesarean delivery under spinal anesthesia with intrathecal morphine, transversus abdominis plane (TAP) block with bupivacaine hydrochloride (HCl) may not improve postsurgical analgesia.
S. Nedeljkovic +11 more
semanticscholar +1 more source
Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer +5 more
doaj +1 more source
Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation
Background: Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable
E. Schwenk +13 more
semanticscholar +1 more source
Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]
In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li +11 more
doaj +1 more source
Background: Co-administration of dexamethasone or neostigmine with local anesthetic solution for caudal block (CB) can prolong postoperative analgesia duration.
Mohamed M. Abu Elyazed, Gehan M. Eid
doaj +1 more source
Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum
Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi +6 more
doaj +1 more source
Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta
Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods.
Mai Mukozawa, Ko Takakura, Maki Mizogami
doaj +1 more source

