Background: Co-administration of dexamethasone or neostigmine with local anesthetic solution for caudal block (CB) can prolong postoperative analgesia duration.
Mohamed M. Abu Elyazed, Gehan M. Eid
doaj +1 more source
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange+8 more
wiley +1 more source
Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta
Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods.
Mai Mukozawa, Ko Takakura, Maki Mizogami
doaj +1 more source
Comparison of Equivalent Doses of Intrathecal Hyperbaric Levo-bupivacaine and Hyperbaric Bupivacaine for Caesarean Section: A Prospective Randomised Double-Blind Study [PDF]
Introduction: Subarachnoid Block (SAB) with Hyperbaric Bupivacaine (HB) is the most common anaesthetic technique for Lower Segment Caesarean Section (LSCS). Levo-bupivacaine, an enantiomer of racemic bupivacaine, has been developed to provide anaesthesia
Noyomi Saring+3 more
doaj +1 more source
BackgroundBreast cancer surgery is one of the most common surgeries among the female population. Nearly half of the patients suffer chronic pain following breast cancer surgery, and 24% of them categorizing their pain as moderate to high.
B. Altıparmak+3 more
semanticscholar +1 more source
Comparison between Epidural Bupivacaine with and without Magnesium Sulphate in Patients undergoing Elective Total Abdominal Hysterectomy: A Double-blinded Randomised Clinical Trial [PDF]
Introduction: The effectiveness of a local anaesthetics increased by the addition of an adjuvant. Magnesium sulphate along with bupivacaine is effective in reducing the pain and extending the analgesia period.
Aishwarya Guru, S Vijay Naraya, B Anusha
doaj +1 more source
Liposomal bupivacaine: a review of a new bupivacaine formulation
Many attempts have been made to increase the duration of local anesthetic action. One avenue of investigation has focused on encapsulating local anesthetics within carrier molecules to increase their residence time at the site of action. This article aims to review the literature surrounding the recently approved formulation of bupivacaine, which ...
Praveen Chahar, Kenneth C. Cummings
openaire +4 more sources
Liposomal Bupivacaine in Single‐Injection Quadratus Lumborum Block for Pediatric Kidney Transplant: Case Report of a Novel Application [PDF]
ABSTRACT Background Liposomal bupivacaine is FDA‐approved long‐acting bupivacaine for intraoperative local wound infiltration in pediatric patients 6 years and older, but not for ultrasound‐guided peripheral nerve blocks. There are few prior reports of using liposomal bupivacaine for preoperative peripheral nerve blocks in pediatric patients. We report
Bonaroti R, Ganoza A, Visoiu M.
europepmc +2 more sources
Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain.
BACKGROUND Despite multi-modal analgesic techniques, acute postoperative pain remains an unmet health need, with up to three quarters of people undergoing surgery reporting significant pain. Liposomal bupivacaine is an analgesic consisting of bupivacaine
T. Hamilton+6 more
semanticscholar +1 more source
The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats. [PDF]
OBJECTIVE:The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal
Qinqin Yin+8 more
doaj +1 more source