Results 21 to 30 of about 76,850 (268)

Comparison between Epidural Bupivacaine with and without Magnesium Sulphate in Patients undergoing Elective Total Abdominal Hysterectomy: A Double-blinded Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: The effectiveness of a local anaesthetics increased by the addition of an adjuvant. Magnesium sulphate along with bupivacaine is effective in reducing the pain and extending the analgesia period.
Aishwarya Guru, S Vijay Naraya, B Anusha
doaj   +1 more source

Comparison of Equivalent Doses of Intrathecal Hyperbaric Levo-bupivacaine and Hyperbaric Bupivacaine for Caesarean Section: A Prospective Randomised Double-Blind Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Subarachnoid Block (SAB) with Hyperbaric Bupivacaine (HB) is the most common anaesthetic technique for Lower Segment Caesarean Section (LSCS). Levo-bupivacaine, an enantiomer of racemic bupivacaine, has been developed to provide anaesthesia
Noyomi Saring, Animesh Namdeo, Millo Apo, Ramapati Sanyal   +3 more
doaj   +1 more source

Comparison of the efficacy of erector spinae plane block performed with different concentrations of bupivacaine on postoperative analgesia after mastectomy surgery: ramdomized, prospective, double blinded trial

BMC Anesthesiology, 2019
BackgroundBreast cancer surgery is one of the most common surgeries among the female population. Nearly half of the patients suffer chronic pain following breast cancer surgery, and 24% of them categorizing their pain as moderate to high.
B. Altıparmak, M. Korkmaz Toker, A. I. Uysal, S. Gümüş Demi̇rbi̇lek   +3 more
semanticscholar   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study

Regional anesthesia and pain medicine, 2019
Background and objectives There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release ...
E. Viscusi, J. Gimbel, R. Pollack, Jia Hu, Gwo-Chin Lee   +4 more
semanticscholar   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in herniorrhaphy: results from the phase 3 EPOCH 2 study

Hernia, 2019
Currently available local anesthetics have not demonstrated sufficient analgesia beyond 12–24 h postoperatively. The purpose of the study was to assess the safety and efficacy of HTX-011 (bupivacaine and meloxicam in Biochronomer® polymer technology), a ...
E. Viscusi, H. Minkowitz, P. Winkle, Sonia Ramamoorthy, J. Hu, N. Singla   +5 more
semanticscholar   +1 more source

Effect of Bupivacaine Liposome Injectable Suspension on Sensory Blockade and Analgesia for Dupuytren Contracture Release

Journal of Hand Surgery Global Online, 2019
Purpose: To study the efficacy of bupivacaine liposome injectable suspension in prolonging sensory blocks of the median and ulnar nerves for subjects with Dupuytren contracture release by collagenase injection.
Catherine F. Vandepitte, MD, PhD, Sam Van Boxstael, MD, Joris F. Duerinckx, MD, Ine Leunen, MD, Maxine M. Kuroda, PhD, MPH, Dieter Mesotten, MD, PhD, Marc Van De Velde, MD, PhD, Admir Hadzic, MD, PhD   +7 more
doaj   +1 more source

Assessment of the Safety and Efficiency of a Preperitoneal Continuous Infusion Using Bupivacaine after Abdominal Laparotomy in Digestive Carcinology

Anesthesiology Research and Practice, 2023
The purpose of this paper is to evaluate the safety and efficacy of continuous preperitoneal wound infiltration using bupivacaine after abdominal laparotomy in relation to plasma bupivacaine concentration and visual analog scale.
Hayat Ben-Saghroune, Mohammed Abdessadek, Sanae Achour, Youssef Kfal, Abderrahim El Bouazzaoui, Nabil Kanjaa, Hicham Sbai   +6 more
doaj   +1 more source

The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats. [PDF]

PLoS ONE, 2017
OBJECTIVE:The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal
Qinqin Yin, Jun Li, Qingshan Zheng, Xiaolin Yang, Rong Lv, Longxiang Ma, Jin Liu, Tao Zhu, Wensheng Zhang   +8 more
doaj   +1 more source

Emerging roles of liposomal bupivacaine in anesthesia practice

Journal of Anaesthesiology Clinical Pharmacology, 2017
Despite advances in drug technology and improvements in technology, including peripheral nerve catheters and ultrasound, postoperative pain is still a significant problem in the clinical setting worldwide.
Obaid S Malik, A. Kaye, A. Kaye, K. Belani, R. Urman   +4 more
semanticscholar   +1 more source