Results 21 to 30 of about 106,557 (332)
BMC Pharmacology and Toxicology, 2021 Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant ...
Hongfei Chen +3 more
doaj +1 more source
The effect of adjuvant midazolam compared with fentanyl on the duration of spinal anesthesia with 0.5% bupivacaine in opium abusers [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundThere are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine
Farhad Safari +2 more
doaj +1 more source
Anesthesiology, 2020 BACKGROUND Liposomal bupivacaine is purported to extend analgesia of peripheral nerve blocks when administered perineurally. However, evidence of the clinical effectiveness of perineural liposomal bupivacaine is mixed.
N. Hussain +6 more
semanticscholar +1 more source
Anesthesiology, 2020 The authors provide a comprehensive summary of all randomized, controlled trials (n = 76) involving the clinical administration of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, USA) to control postoperative pain that are currently published ...
B. Ilfeld, J. Eisenach, R. Gabriel
semanticscholar +1 more source
Anesthesia and Analgesia, 2020 BACKGROUND: In women undergoing cesarean delivery under spinal anesthesia with intrathecal morphine, transversus abdominis plane (TAP) block with bupivacaine hydrochloride (HCl) may not improve postsurgical analgesia.
S. Nedeljkovic +11 more
semanticscholar +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, 2020 Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer +5 more
doaj +1 more source
Gynecologic Oncology Reports, 2023 Background: To evaluate whether incisional infiltration of liposomal bupivacaine would decrease opioid requirement and pain scores after midline vertical laparotomy for suspected or known gynecologic malignancy compared with transversus abdominis plane ...
Ashley S. Moon +7 more
doaj +1 more source
Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation
Anesthesiology, 2020 Background: Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable
E. Schwenk +13 more
semanticscholar +1 more source
Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]
PLoS ONE, 2018 In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li +11 more
doaj +1 more source
Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum
Journal of Anaesthesiology Clinical Pharmacology, 2023 Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi +6 more
doaj +1 more source