Results 31 to 40 of about 42,379 (196)

Bupivacaine (0.5%) Versus (0.5%) Bupivacaine with Ketamine (50 mg) for Subarachnoid Block in Lower Abdominal Surgeries: A Randomised Comparative Study [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Spinal anaesthesia is the preferred technique for most of the lower abdominal surgeries nowadays. Currently, Bupivacaine is the most commonly used drug in spinal anaesthesia.
Bhargav Vishnu Gantasala, Amol Singam, Karuna Talsande   +2 more
doaj   +1 more source

Incisional infiltration versus transversus abdominis plane block of liposomal bupivacaine after midline vertical laparotomy for suspected gynecologic malignancy: a pilot study

Gynecologic Oncology Reports, 2023
Background: To evaluate whether incisional infiltration of liposomal bupivacaine would decrease opioid requirement and pain scores after midline vertical laparotomy for suspected or known gynecologic malignancy compared with transversus abdominis plane ...
Ashley S. Moon, Vaagn Andikyan, Rakhee Agarwal, Stephanie Stroever, David Misita, Anya Laibangyang, David Doo, Linus T. Chuang   +7 more
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Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BMC Veterinary Research, 2020
Background Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy.
Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Max Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko   +7 more
doaj   +1 more source

Comparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2 mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor

Journal of Nepal Medical Association, 2007
Analgesia during labor provided by two epidural drug regimens was compared in a double blind, randomized, prospective study. Group A (n = 12) received 10 ml bolus doses of 0.1% bupivacaine with butorphanol 2 mg while Group B (n = 8) received 10 ml of 0 ...
CK Shrestha, KR Sharma, RR Shrestha
doaj   +1 more source

Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells

BMC Neuroscience, 2012
Background Bupivacaine-induced neurotoxicity has been shown to occur through apoptosis. Recently, bupivacaine was shown to elicit reactive oxygen species (ROS) production and induce apoptosis accompanied by activation of p38 mitogen-activated protein ...
Harato Misako, Huang Lei, Kondo Fumio, Tsunekawa Koji, Feng Guo-Gang, Fan Jun-Hua, Ishikawa Naohisa, Fujiwara Yoshihiro, Okada Shoshiro   +8 more
doaj   +1 more source

The safety of liposome bupivacaine following various routes of administration in animals

Journal of Pain Research, 2015
Girish P Joshi,1 Gary Patou,2 Vladimir Kharitonov21Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX, 2Pacira Pharmaceuticals, Inc., Parsippany, NJ, USABackground: This report presents results ...
Joshi GP, Patou G, Kharitonov V
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Efficacy and safety of different bupivacaine concentrations in periarticular infiltration combined with adductor canal block for bilateral total knee arthroplasty: a randomized controlled trial

Knee Surgery & Related Research
Background Pain management for bilateral total knee arthroplasty (BTKA) often combines adductor canal block (ACB) with periarticular infiltration (PAI). However, concerns arise regarding local anesthetic toxicity.
Sukanya Dej-arkom, Pawinee Pangthipampai, Weerawadee Chandranipapongse, Somruedee Chatsirichareonkul, Rapeepat Narkbunnam, Keerati Charoencholvanich, Suwida Tangchittam, Arissara Iamaroon   +7 more
doaj   +1 more source

Dexamethasone as adjuvant to bupivacaine prolongs the duration of thermal antinociception and prevents bupivacaine-induced rebound hyperalgesia via regional mechanism in a mouse sciatic nerve block model. [PDF]

PLoS ONE, 2015
BACKGROUND:Dexamethasone has been studied as an effective adjuvant to prolong the analgesia duration of local anesthetics in peripheral nerve block. However, the route of action for dexamethasone and its potential neurotoxicity are still unclear. METHODS:
Ke An, Nabil M Elkassabany, Jiabin Liu
doaj   +1 more source

Post-Cardiotomy Parasternal Nerve Block with Bupivacaine May Be Associated with Reduced Post-Operative Opioid Use in Children: A Retrospective Cohort Study

Children, 2020
Postoperative pain treatment affects immediate and long-term outcomes in children undergoing cardiac surgery. Opioids, as part of multimodal analgesia, are effective in treating pain, however, they can be disadvantageous due to adverse side effects ...
Francis X. Moga, Mark D. Lo Galbo, David M. Overman, Stefan J. Friedrichsdorf   +3 more
doaj   +1 more source

An evaluation of the analgesic effect of AnestaGel™ on mechanical allodynia in a rat model of postoperative incisional pain

Journal of Pain Research, 2017
Jacob Hutchins,1 William Taylor2 1Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA; 2InSitu Biologics, LLC, St Paul, MN, USA Purpose: Sustained release hydrogel with bupivacaine (AnestaGel™) is a novel formulation of ...
Hutchins J, Taylor W
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