Results 41 to 50 of about 74,417 (287)

Are reinfusion drains safe to use with periarticular liposomal bupivacaine? An analysis of systemic bupivacaine toxicity

Arthroplasty Today, 2018
Background: Intraoperative periarticular injection (PAI) with local anesthetic is an important component of multimodal pain control in total joint arthroplasty (TJA).
Marc R. Angerame, MD, Gavin P. Hart, MD, Susan M. Odum, PhD, Bryan D. Springer, MD   +3 more
doaj   +1 more source

Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BMC Veterinary Research, 2020
Background Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy.
Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Max Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko   +7 more
doaj   +1 more source

COMPARISON OF CARBONATED BUPIVACAINE AND BUPIVACAINE HYDROCHLORIDE FOR EXTRADURAL ANAESTHESIA

British Journal of Anaesthesia, 1980
A double-blind comparison of carbonated bupivacaine and bupivacaine hydrochloride in extradural anaesthesia was performed in 40 patients. No significant differences in the onset times, sensory blockade, motor blockade and duration of anaesthesia were demonstrated. Carbonated bupivacaine does not appear to offer any advantage over the hydrochloride salt
B.G. Covino, D.T. Brown, D.H. Morison, D.B. Scott   +3 more
openaire   +3 more sources

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Post-operative pain and analgesic requirements after paravertebral block for mastectomy: A randomized controlled trial of different concentrations of bupivacaine and fentanyl

Indian Journal of Anaesthesia, 2012
Background: Paravertebral block (PVB) is useful for post-operative analgesia after breast surgery. Bupivacaine is used for PVB at higher concentrations (0.5%), which may lead to systemic toxicity after absorption.
V Bhuvaneswari, Jyotsna Wig, Preethy J Mathew, Gurpreet Singh   +3 more
doaj   +1 more source

Response to “Bupivacaine Liposomal versus Bupivacaine: Comparative Review” [PDF]

Hospital Pharmacy, 2014
To the Editor: The recent article, “Bupivacaine Liposomal Versus Bupivacaine: Comparative Review,” by Noviasky et al [Hosp Pharm. 2014;49(6):539-543] is a valiant effort to review this topic. However, the authors have made a critical oversight in their attempt to interpret analgesic efficacy based solely on pain intensity.
openaire   +3 more sources

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

Advanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim, Hyeongseop Keum, Hassan Albadawi, Ismail Altinbasak, Furkan Yavuz, Erin H. Graf, Nitin Mishra, Rahmi Oklu   +7 more
wiley   +1 more source

Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro

Scientific Reports, 2016
Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
W. Xuan, Hailin Zhao, J. Hankin, Lin Chen, S. Yao, D. Ma   +5 more
semanticscholar   +1 more source

Cold Plasma Generates a Localized Inflammatory Response and Promotes Muscle Repair

Advanced Therapeutics, EarlyView.
The immediate tissue response to plasma is a pro‐inflammatory response which is characterized by collagen clumping, innate immune cell infiltration, enhanced metabolic processes, and decreased apoptosis. The long‐term tissue response (4‐ and 14‐days) to plasma treatment is characterized by a decreased inflammatory response, decreased adipogenesis, and ...
Carly J. Smith, Amanda R. Watkins, Abigail A. Lucas, Arianna J. Moniodes, Conn Ritchie, Thomas P. Thompson, Thomas P. Schaer, Brendan F. Gilmore, Noreen J. Hickok, Theresa A. Freeman   +9 more
wiley   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

Advanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang, Xiuru Ji, Yu Sun, Han Wang, Ting Wang, Tao Luo, Yanyong Cheng, Jia Yan, Dalong Ni, Hong Jiang   +9 more
wiley   +1 more source