Results 41 to 50 of about 104,086 (361)

Comparison between Epidural Bupivacaine with and without Magnesium Sulphate in Patients undergoing Elective Total Abdominal Hysterectomy: A Double-blinded Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: The effectiveness of a local anaesthetics increased by the addition of an adjuvant. Magnesium sulphate along with bupivacaine is effective in reducing the pain and extending the analgesia period.
Aishwarya Guru, S Vijay Naraya, B Anusha
doaj   +1 more source

Comparison of the efficacy of erector spinae plane block performed with different concentrations of bupivacaine on postoperative analgesia after mastectomy surgery: ramdomized, prospective, double blinded trial

BMC Anesthesiology, 2019
BackgroundBreast cancer surgery is one of the most common surgeries among the female population. Nearly half of the patients suffer chronic pain following breast cancer surgery, and 24% of them categorizing their pain as moderate to high.
B. Altıparmak, M. Korkmaz Toker, A. I. Uysal, S. Gümüş Demi̇rbi̇lek   +3 more
semanticscholar   +1 more source

Comparison of Equivalent Doses of Intrathecal Hyperbaric Levo-bupivacaine and Hyperbaric Bupivacaine for Caesarean Section: A Prospective Randomised Double-Blind Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Subarachnoid Block (SAB) with Hyperbaric Bupivacaine (HB) is the most common anaesthetic technique for Lower Segment Caesarean Section (LSCS). Levo-bupivacaine, an enantiomer of racemic bupivacaine, has been developed to provide anaesthesia
Noyomi Saring, Animesh Namdeo, Millo Apo, Ramapati Sanyal   +3 more
doaj   +1 more source

Benefits of thoracic epidural analgesia in patients undergoing an open posterior component separation for abdominal herniorrhaphy [PDF]

, 2017
INTRODUCTION: The implementation of open posterior component separation (PCS) surgery has led to improved outcomes for complex hernias. While the PCS technique has been shown to decrease recurrence rates, and provide a feasible option to repair hernias ...
Sellers, Austin
core   +1 more source

Is surgery more effective than non-surgical treatment for spinal stenosis and which non-surgical treatment is more effective? a systematic review [PDF]

, 2013
BACKGROUND: Spinal stenosis can be treated both conservatively and with decompression surgery. OBJECTIVES: To explore the effectiveness of surgery vs conservative treatment, and conservative interventions for spinal stenosis.
Comer, C, May, Stephen
core   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in herniorrhaphy: results from the phase 3 EPOCH 2 study

Hernia, 2019
Currently available local anesthetics have not demonstrated sufficient analgesia beyond 12–24 h postoperatively. The purpose of the study was to assess the safety and efficacy of HTX-011 (bupivacaine and meloxicam in Biochronomer® polymer technology), a ...
E. Viscusi, H. Minkowitz, P. Winkle, Sonia Ramamoorthy, J. Hu, N. Singla   +5 more
semanticscholar   +1 more source

The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats. [PDF]

PLoS ONE, 2017
OBJECTIVE:The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal
Qinqin Yin, Jun Li, Qingshan Zheng, Xiaolin Yang, Rong Lv, Longxiang Ma, Jin Liu, Tao Zhu, Wensheng Zhang   +8 more
doaj   +1 more source

Effect of Bupivacaine Liposome Injectable Suspension on Sensory Blockade and Analgesia for Dupuytren Contracture Release

Journal of Hand Surgery Global Online, 2019
Purpose: To study the efficacy of bupivacaine liposome injectable suspension in prolonging sensory blocks of the median and ulnar nerves for subjects with Dupuytren contracture release by collagenase injection.
Catherine F. Vandepitte, MD, PhD, Sam Van Boxstael, MD, Joris F. Duerinckx, MD, Ine Leunen, MD, Maxine M. Kuroda, PhD, MPH, Dieter Mesotten, MD, PhD, Marc Van De Velde, MD, PhD, Admir Hadzic, MD, PhD   +7 more
doaj   +1 more source

Synergistic drug combinations from electronic health records and gene expression. [PDF]

, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William, Daugherty, Aaron C, Desai, Manisha, Farrington, Carl, Gomez, Scarlett L, Hastie, Trevor, Kenkare, Pragati, Kurian, Allison W, Lim, Michael, Low, Yen S, Mathur, Maya, Radin, Andrew A, Schroeder, Elizabeth A, Seto, Tina, Shah, Nigam H, Sirota, Marina, Sledge, George W, Thompson, Caroline A, Weber, Susan, Yu, Peter P   +19 more
core   +2 more sources

Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine

British Journal of Anaesthesia, 1998
Bupivacaine has a chiral centre and is currently available as a racemic mixture of its two enantiomers: R(+)-bupivacaine and S(-)-bupivacaine. Preclinical studies have demonstrated that there is enantiomer selectivity of action with the bulk of central nervous system and cardiovascular toxicity residing with the R(+) isomer.
C. R. Cox, N. B. Scott, K. A. Faccenda, J. Bannister, L. M. M. Morrison, Charlotte Gilhooly   +5 more
openaire   +3 more sources