Results 41 to 50 of about 106,557 (332)

The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats. [PDF]

PLoS ONE, 2017
OBJECTIVE:The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal
Qinqin Yin, Jun Li, Qingshan Zheng, Xiaolin Yang, Rong Lv, Longxiang Ma, Jin Liu, Tao Zhu, Wensheng Zhang   +8 more
doaj   +1 more source

The challenge of evaluating pain and a pre-incisional local anesthetic block. [PDF]

, 2014
Background. Our objective was to test the effectiveness of a local anesthetic line block administered before surgery in reducing postoperative pain scores in dogs undergoing ovariohysterectomy (OVHX). Methods.
Kass, Philip H, Lascelles, B Duncan X, McKune, Carolyn M, Pascoe, Peter J   +3 more
core   +2 more sources

Emerging roles of liposomal bupivacaine in anesthesia practice

Journal of Anaesthesiology Clinical Pharmacology, 2017
Despite advances in drug technology and improvements in technology, including peripheral nerve catheters and ultrasound, postoperative pain is still a significant problem in the clinical setting worldwide.
Obaid S Malik, A. Kaye, A. Kaye, K. Belani, R. Urman   +4 more
semanticscholar   +1 more source

Effect of Bupivacaine Liposome Injectable Suspension on Sensory Blockade and Analgesia for Dupuytren Contracture Release

Journal of Hand Surgery Global Online, 2019
Purpose: To study the efficacy of bupivacaine liposome injectable suspension in prolonging sensory blocks of the median and ulnar nerves for subjects with Dupuytren contracture release by collagenase injection.
Catherine F. Vandepitte, MD, PhD, Sam Van Boxstael, MD, Joris F. Duerinckx, MD, Ine Leunen, MD, Maxine M. Kuroda, PhD, MPH, Dieter Mesotten, MD, PhD, Marc Van De Velde, MD, PhD, Admir Hadzic, MD, PhD   +7 more
doaj   +1 more source

Assessment of the Safety and Efficiency of a Preperitoneal Continuous Infusion Using Bupivacaine after Abdominal Laparotomy in Digestive Carcinology

Anesthesiology Research and Practice, 2023
The purpose of this paper is to evaluate the safety and efficacy of continuous preperitoneal wound infiltration using bupivacaine after abdominal laparotomy in relation to plasma bupivacaine concentration and visual analog scale.
Hayat Ben-Saghroune, Mohammed Abdessadek, Sanae Achour, Youssef Kfal, Abderrahim El Bouazzaoui, Nabil Kanjaa, Hicham Sbai   +6 more
doaj   +1 more source

Is surgery more effective than non-surgical treatment for spinal stenosis and which non-surgical treatment is more effective? a systematic review [PDF]

, 2013
BACKGROUND: Spinal stenosis can be treated both conservatively and with decompression surgery. OBJECTIVES: To explore the effectiveness of surgery vs conservative treatment, and conservative interventions for spinal stenosis.
Comer, C, May, Stephen
core   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in herniorrhaphy: results from the phase 3 EPOCH 2 study

Hernia, 2019
Currently available local anesthetics have not demonstrated sufficient analgesia beyond 12–24 h postoperatively. The purpose of the study was to assess the safety and efficacy of HTX-011 (bupivacaine and meloxicam in Biochronomer® polymer technology), a ...
E. Viscusi, H. Minkowitz, P. Winkle, Sonia Ramamoorthy, J. Hu, N. Singla   +5 more
semanticscholar   +1 more source

COMPARISON OF HAEMODYNAMIC STABILITY WITH 0.5% AND 0.75% HYPERBARIC BUPIVACAINE DURING SPINAL ANAESTHESIA IN WOMEN UNDERGOING CAESAREAN SECTION

Pakistan Armed Forces Medical Journal, 2021
Objective: To compare the effect of 0.5% and 0.75% hyperbaric Bupivacaine on haemodynamic stability in terms of mean systolic blood pressure and heart rate recorded at 4 min in patients undergoing caesarian section in spinal anesthesia.
Hina Iftikhar, Aneel Aslam, Habib Ur Rehman, Zulfiqar Ali, Mohammad Ali Abbass, Zulfiqar Haider   +5 more
doaj  

ROS-mediated lysosomal membrane permeabilization is involved in bupivacaine-induced death of rabbit intervertebral disc cells

Redox Biology, 2018
Bupivacaine is frequently administered for diagnosing and controlling spine-related pain in interventional spine procedures. However, the potential cytotoxic effects of bupivacaine on intervertebral disc (IVD) cells and the underlying molecular ...
Xianyi Cai, Yunlu Liu, Yiqiang Hu, Xianzhe Liu, Hongyan Jiang, Shuhua Yang, Zengwu Shao, Yun Xia, Liming Xiong   +8 more
doaj   +1 more source

Transversus abdominis plane blocks; a national survey of techniques used by UK obstetric anaesthetists [PDF]

, 2011
No abstract ...
Kearns, R.J., Young, S.J.
core   +1 more source