Results 61 to 70 of about 102,685 (330)

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator [PDF]

, 2018
We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel ...
Joseph, Ancy, Okada, Masayoshi, Thanh, Le Tat, Thuy, Tran Thi Thu   +3 more
core   +2 more sources

Comparison of caudal bupivacaine, bupivacaine-morphine and bupivacaine-midazolam mixtures for post-operative analgesia in children

European Journal of Anaesthesiology, 1998
Sixty children undergoing inguinal or urogenital surgery were allocated randomly to three groups to receive a caudal injection of either 0.125% bupivacaine 0.75 mL kg-1 with 0.5% midazolam 50 micrograms kg-1 (n = 20) or with 1% morphine chlorhydrate 0.05 mg kg-1 (n = 20), or bupivacaine alone (n = 20) after surgery under general anaesthesia. There were
B. Büyükkidan, N. Özcan, N. Oral, Sacit Güleç, B. Tanriverdi   +4 more
openaire   +4 more sources

Exploring Resource Recovery Technologies for Medicinal Cannabis Waste

ChemBioEng Reviews, EarlyView.
This review highlights the different types of sustainable treatment methods that are available for medicinal cannabis processing. There are challenges that occur throughout processing, mainly the legislative issues that issues from handling the waste. Several methods are discussed within this article on correctly treating medicinal cannabis waste in a ...
Kerry Jack Robertson, Rupinder Brar, Parmjit Randhawa, Christine Stark, Saeid Baroutian   +4 more
wiley   +1 more source

SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]

, 1989
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core   +1 more source

Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BMC Veterinary Research, 2020
Background Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy.
Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Max Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko   +7 more
doaj   +1 more source

Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage

Glia, EarlyView.
NBCe1 is upregulated in reactive astrocytes following ischemic stroke. Deletion of astrocytic Nbce1 reduces stroke volume, preserves AQP4 polarization, reduces BBB permeability, and improves neurological function after ischemic stroke. ABSTRACT The electrogenic sodium bicarbonate transporter 1 (NBCe1/Slc4a4), predominantly expressed in astrocytes, is ...
Okan Capuk, Elise Berthold, Kathiravan Kaliyappan, Mansi Avunoori, Rajesh Muduganti, Sanjana Krishna, Shamseldin Metwally, Mary McFarland, Shanshan Song, Victoria Fiesler, Sydney Fischer, Lesley M. Foley, T. Kevin Hitchens, Susannah Waxman, Ian A. Sigal, Shefeeq M. Theparambil, Gulnaz Begum   +16 more
wiley   +1 more source

Clinical Characteristics and Influencing Factors of Postoperative Pain in Patients Undergoing Gastric Endoscopic Submucosal Dissection

Health Care Science, EarlyView.
Endoscopic submucosal dissection (ESD) causes post‐procedural pain. Independent influencing factors for pain after gastric ESD: Female gender, diabetes mellitus concavitive lesions lesions on the gastric antrum non‐intubation general anesthesia without intraoperative electrocoagulation, prolonged operation, nasogastric tube, and postoperative vomiting.
Fen Deng, Liru Pan, Lei Tao, Xiaoyu Qiu, Bing Li, Jing Hao, Huihui Li, Zhenzhen Zhang, Weiwei Ding, Yingying Wang, Bo Ning   +10 more
wiley   +1 more source

Comparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2 mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor

Journal of Nepal Medical Association, 2007
Analgesia during labor provided by two epidural drug regimens was compared in a double blind, randomized, prospective study. Group A (n = 12) received 10 ml bolus doses of 0.1% bupivacaine with butorphanol 2 mg while Group B (n = 8) received 10 ml of 0 ...
CK Shrestha, KR Sharma, RR Shrestha
doaj   +1 more source

Leveraging Point‐Of‐Care Ultrasound to Diagnose a Rare Arterial Occlusive Thrombus in a Child: A Case Study

Journal of Clinical Ultrasound, EarlyView.
This case report illustrates the successful use of ultrasound imaging of arterial thrombosis in a child following orthopedic surgery, where regular diagnosis was difficult due to the presence of metallic orthopedic frames. ABSTRACT Pediatric arterial thromboembolism is an extremely rare and serious complication, especially rare when it is noncatheter ...
Vrushali C. Ponde, Neha Singh, Ashok N. Johari, Hanna Smeds, Karen Boretsky   +4 more
wiley   +1 more source