Results 1 to 10 of about 8,432 (165)
Cerebral Circulation - Cognition and Behavior, 2021 Aim: Our study aimed to test whether plasma acetylcholinesterase and butyrylcholinesterase enzyme activity were related to the presence and intensity of delirium in acute stroke patients.
Lara Caeiro +5 more
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Pharmaceuticals, 2023 Twenty-one analogs were synthesized based on benzimidazole, incorporating a substituted benzaldehyde moiety (1–21). These were then screened for their acetylcholinesterase and butyrylcholinesterase inhibition profiles.
Bushra Adalat +11 more
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Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase. [PDF]
PLoS ONE, 2013 Concerns about the safety of paralytics such as succinylcholine to facilitate endotracheal intubation limit their use in prehospital and emergency department settings.
Brian C Geyer +4 more
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Pharmaceuticals, 2022 2,5-Disubstituted 1,3,4-oxadiazoles are privileged versatile scaffolds in medicinal chemistry that have exhibited diverse biological activities. Acetyl- (AChE) and butyrylcholinesterase (BChE) inhibitors are used, e.g., to treat dementias and myasthenia ...
Václav Pflégr +5 more
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Wide awake under anesthesia: Scoline apnoea update [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2016 Butyrylcholinesterase (BChE) catalyses the hydrolysis of choline esters and thus deactivates muscle relaxants such as succinylcholine and mivacurium. The prolonged neuromuscular blockade following the use of succinylcholine, called scoline apnea, occurs ...
Marković Danica, Janković Radmilo J.
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Software for Matching Standard Activity Enzyme Biosensors for Soil Pollution Analysis
Sensors, 2021 This work is dedicated to developing enzyme biosensor software to solve problems regarding soil pollution analysis. An algorithm and specialised software have been developed which stores, analyses and visualises data using JavaScript programming language.
Valentina A. Kratasyuk +7 more
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Can Marine Products Improve Alzheimer’s Disease [PDF]
Journal of Sciences, Islamic Republic of Iran, 2020 Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore ...
Hamid-Reza Adhami, Paria Sharafi
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Surrogate Markers of the Kidney and Liver in the Assessment of Gestational Diabetes Mellitus and Fetal Outcome [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: To investigate whether serum levels of butyrylcholinesterase activity, cystatin C, and pre-albumin has the potential value as γ-glutamyl transferase in reflecting gestational diabetes mellitus and its fetal outcome. Materials and Methods:
Hong Liu +4 more
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Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold. [PDF]
PLoS ONE, 2018 This paper describes the synthesis and anticholinesterase potency of Cinchona-based alkaloids; ten quaternary derivatives of cinchonines and their corresponding pseudo-enantiomeric cinchonidines. The quaternization of quinuclidine moiety of each compound
Anita Bosak +5 more
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Molecules, 2021 Alzheimer’s disease (AD) is a progressive age-related neurodegenerative disease recognized as the most common form of dementia among elderly people. Due to the fact that the exact pathogenesis of AD still remains to be fully elucidated, the treatment is ...
Lucie Cahlíková +8 more
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