Results 21 to 30 of about 16,092 (168)

Association between butyrylcholinesterase K variant and mild cognitive impairment in the Thai community-dwelling patients [PDF]

, 2017
Natsalil Pongthanaracht,1 Somchai Yanarojana,1 Darawan Pinthong,1 Supeenun Unchern,1 Amnuay Thithapandha,1 Prasert Assantachai,2 Porntip Supavilai11Department of Pharmacology, Faculty of Science, 2Department of Preventive and Social Medicine, Faculty of ...
Somchai Yanarojana, Pinthong D, Pongthanaracht N, Unchern S, Thithapandha A, Supeenun Unchern, Natsalil Pongthanaracht, Porntip Supavilai, Yanarojana S, Amnuay Thithapandha, Supavilai P, Assantachai P, Prasert Assantachai, Darawan Pinthong   +13 more
core   +1 more source

Evaluation of derivatives of 2,3-dihydroquinazolin-4(1H)-one as inhibitors of cholinesterases and their antioxidant activity: In vitro, in silico, and kinetics studies [PDF]

Journal of the Serbian Chemical Society, 2023
In search of potent inhibitors of cholinesterase enzymes and antioxidant agents, synthetic derivatives of dihydroquinazolin-4(1H)-one (1–38) were evaluated as potential anti-Alzheimer agents through in vitro acetylcholinesterase (AChE) and ...
Babatunde Oluwatoyin, Hameed Shehryar, Mbachu Kingsley Adibe, Saleem Faiza, Chigurupati Sridevi, Wadood Abdul, Ur Rehman Ashfaq, Venugopal Vijayan, Khan Khalid Mohammed, Taha Muhammad, Ekundayo Olusegun, Khan Maria Aqeel   +11 more
doaj   +1 more source

Influence of obstructive sleep apnea on serum butyrylcholinesterase activity and ischemia-modified albumin levels

Clinics, 2013
OBJECTIVE: To investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels.
Liu-Xue Yang, Shao-Gang Ma, Hong Liu, Wei Xu   +3 more
doaj   +1 more source

Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development

Molecules, 2017
Human butyrylcholinesterase is a performant stoichiometric bioscavenger of organophosphorous nerve agents. It is either isolated from outdated plasma or functionally expressed in eukaryotic systems.
Xavier Brazzolotto, Alexandre Igert, Virginia Guillon, Gianluca Santoni, Florian Nachon   +4 more
doaj   +1 more source

Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach

Lipids in Health and Disease, 2005
Background Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide sequences downloaded from NCBI ...
Sreelatha S, Madhavi AS, Apparao Allam, Nirmala G, Sridhar GR, Rani J Sudha, Vijayalakshmi P   +6 more
doaj   +1 more source

Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine

Molecules, 2022
Magnofluorine, a secondary metabolite commonly found in various plants, has pharmacological potential; however, its antioxidant and enzyme inhibition effects have not been investigated.
Lokman Durmaz, Hatice Kiziltas, Leyla Guven, Hasan Karagecili, Saleh Alwasel, İlhami Gulcin   +5 more
doaj   +1 more source

Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity

Molecules, 2022
Transformations of 1-methoxymethylethynyl substituted isoquinolines triggered by terminal alkynes in alcohols were studied and new 3-benzazecine-containing compounds synthesized, such as 6-methoxymethyl-3-benzazecines incorporating an endocyclic C6–C8 ...
Alexander A. Titov, Rosa Purgatorio, Arina Y. Obydennik, Anna V. Listratova, Tatiana N. Borisova, Modesto de Candia, Marco Catto, Cosimo D. Altomare, Alexey V. Varlamov, Leonid G. Voskressensky   +9 more
doaj   +1 more source

Critically Ill COVID-19 Patients Show Reduced Point of Care-Measured Butyrylcholinesterase Activity—A Prospective, Monocentric Observational Study

Diagnostics, 2022
A biomarker for risk stratification and disease severity assessment in SARS-CoV-2 infections has not yet been established. Point of care testing (POCT) of butyrylcholinesterase (BChE) enables early detection of systemic inflammatory responses and ...
Florian Espeter, David Künne, Lena Garczarek, Henning Kuhlmann, Annabell Skarabis, Aleksandar R. Zivkovic, Thorsten Brenner, Karsten Schmidt   +7 more
doaj   +1 more source

Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice

Biology, 2021
Butyrylcholinesterase (BChE) is detected in plaques preferentially in Alzheimer’s disease (AD) and may be associated with stress disorders. However, the physiological function of BChE in the central nervous system remains to be further investigated. BChE
Weiwei Liu, Yan Cao, Yue Lin, Keai Sinn Tan, Haishan Zhao, Haihua Guo, Wen Tan   +6 more
doaj   +1 more source

Butyrylcholinesterase: impact on symptoms and progression of cognitive impairment

The most successful approach for treating people with Alzheimer\u27s disease to date has been by improving cholinergic transmission using cholinesterase inhibitors. Many of these drugs selectively inhibit acetylcholinesterase but some agents inhibit both
Ballard CG, Perry EK, Tasker A
core   +5 more sources