Results 41 to 50 of about 14,314 (224)

Butyrylcholinesterase–Protein Interactions in Human Serum [PDF]

International Journal of Molecular Sciences, 2021
Measuring various biochemical and cellular components in the blood is a routine procedure in clinical practice. Human serum contains hundreds of diverse proteins secreted from all cells and tissues in healthy and diseased states. Moreover, some serum proteins have specific strong interactions with other blood components, but most interactions are ...
Jacek Jasiecki, Anna Szczoczarz, Dominik Cysewski, Krzysztof Lewandowski, Piotr Skowron, Krzysztof Waleron, Bartosz Wasąg   +6 more
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Butyrylcholinesterase and Cognitive Function

International Psychogeriatrics, 2001
Butyrylcholinesterase (BuChE) is expressed in brain structures involved in cognition, but the effect of selective BuChE inhibitors on human cognitive function is unknown. We report a patient whose cognitive function deteriorated following a reduction and improved following reinstitution of ethopropazine, a selective BuChE inhibitor.
S, Darvesh, C, MacKnight, K, Rockwood
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Hupresin Retains Binding Capacity for Butyrylcholinesterase and Acetylcholinesterase after Sanitation with Sodium Hydroxide

Frontiers in Pharmacology, 2017
Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in human plasma binds to Hupresin and
Seda Onder, Seda Onder, Emilie David, Ozden Tacal, Lawrence M. Schopfer, Oksana Lockridge   +5 more
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Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase [PDF]

Chemistry – A European Journal, 2019
AbstractOrganophosphorus (OP) nerve agents and pesticides present significant threats to civilian and military populations. OP compounds include the nefarious G and V chemical nerve agents, but more commonly, civilians are exposed to less toxic OP pesticides, resulting in the same negative toxicological effects and thousands of deaths on an annual ...
Andrew J. Franjesevic, Sydney B. Sillart, Jeremy M. Beck, Shubham Vyas, Christopher S. Callam, Christopher M. Hadad   +5 more
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Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora

International Journal of Secondary Metabolite, 2017
Erica species are generally spread along the coasts of Turkey. There are five Erica species in these regions, namely; E. arborea, E. manipuliflora, E, bocquetii, E. sicula subsp. Libanotica and E. spiculifolia salisb.
Çiğdem Kuş, Mehmet Emin Duru, Selçuk Küçükaydın   +2 more
doaj   +1 more source

Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2) [PDF]

, 1990
DNA of 3 unrelated individuals carrying the human plasma butyrylcholinesterase C5 variant (CHE2) was isolated from white blood cells. Southern blot patterns of DNA restriction fragments probed with each of the 4 butyrylcholinesterase exons provided ...
Chatonnet, Arnaud, Lockridge, Oksana, Masson, Patrick, Oksana Lockridge, Patrick Masson, Arnaud Chatonnet   +5 more
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Association between butyrylcholinesterase K variant and mild cognitive impairment in the Thai community-dwelling patients

, 2017
Natsalil Pongthanaracht,1 Somchai Yanarojana,1 Darawan Pinthong,1 Supeenun Unchern,1 Amnuay Thithapandha,1 Prasert Assantachai,2 Porntip Supavilai11Department of Pharmacology, Faculty of Science, 2Department of Preventive and Social Medicine, Faculty of ...
Somchai Yanarojana, Pinthong D, Pongthanaracht N, Unchern S, Thithapandha A, Supeenun Unchern, Natsalil Pongthanaracht, Porntip Supavilai, Yanarojana S, Amnuay Thithapandha, Supavilai P, Assantachai P, Prasert Assantachai, Darawan Pinthong   +13 more
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Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma

Chemico-Biological Interactions, 2016
Five mouse anti-human butyrylcholinesterase (BChE) monoclonal antibodies bind tightly to native human BChE with nanomolar dissociation constants. Pairing analysis in the Octet system identified the monoclonal antibodies that bind to overlapping and independent epitopes on human BChE.
Peng, Hong, Brimijoin, Stephen, Hrabovska, Anna, Krejci, Eric, Blake, Thomas, Johnson, Rudolph, Masson, Patrick, Lockridge, Oksana   +7 more
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Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering

Advanced Science, 2020
Organophosphate nerve agents rapidly inhibit cholinesterases thereby destroying the ability to sustain life. Strong nucleophiles, such as oximes, have been used as therapeutic reactivators of cholinesterase‐organophosphate complexes, but suffer from ...
Libin Zhang, Stefanie L. Baker, Hironobu Murata, Nicholas Harris, Weihang Ji, Gabriel Amitai, Krzysztof Matyjaszewski, Alan J. Russell   +7 more
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Synthesis of Benzimidazole–Based Analogs as Anti Alzheimer’s Disease Compounds and Their Molecular Docking Studies

Molecules, 2020
We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and ...
Bushra Adalat, Fazal Rahim, Muhammad Taha, Foziah J. Alshamrani, El Hassane Anouar, Nizam Uddin, Syed Adnan Ali Shah, Zarshad Ali, Zainul Amiruddin Zakaria   +8 more
doaj   +1 more source