Results 11 to 20 of about 14,314 (224)

Butyrylcholinesterase deficiency identified after succinylcholine administration. Case report

Iatreia, 2018
The main function of the enzyme butyrylcholinesterase is to hydrolyze exogenous esters such as those present in the neuromuscular blocking agent succinylcholine, which is frequently used in short surgical procedures.
Manzano Rincón, Yolima, Castillo Cabellos, Jhuliana Mercedes, Gualdrón Frías, Carlos Andrés, Vega Useche, Leonel Santiago   +3 more
doaj   +2 more sources

Cord Blood Butyrylcholinesterase Activities in Normal Pregnant and Preeclamptic Women

Avicenna Journal of Medical Biochemistry, 2016
Background Human placenta, a non-neural tissue, contains cholinergic system and high-affinity muscarinic receptors. The role of cholinesterases (CE) in trophoblast function and pregnancy is not clear. Objectives
Kharb, Panjeta, Kala, Ghalaut, Bala, Nanda   +5 more
doaj   +2 more sources

The role of acetylcholinesterase and butyrylcholinesterase activity in the development of delirium in acute stroke

Cerebral Circulation - Cognition and Behavior, 2021
Aim: Our study aimed to test whether plasma acetylcholinesterase and butyrylcholinesterase enzyme activity were related to the presence and intensity of delirium in acute stroke patients.
Lara Caeiro, Filipa Novais, Carlota Saldanha, Teresa Pinho e Melo, Patrícia Canhão, José M. Ferro   +5 more
doaj   +2 more sources

Influence of obstructive sleep apnea on serum butyrylcholinesterase activity and ischemia-modified albumin levels

Clinics, 2013
OBJECTIVE: To investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels.
Liu-Xue Yang, Shao-Gang Ma, Hong Liu, Wei Xu   +3 more
doaj   +2 more sources

Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase. [PDF]

PLoS ONE, 2013
Concerns about the safety of paralytics such as succinylcholine to facilitate endotracheal intubation limit their use in prehospital and emergency department settings.
Brian C Geyer, Katherine E Larrimore, Jacquelyn Kilbourne, Latha Kannan, Tsafrir S Mor   +4 more
doaj   +3 more sources

Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development

Molecules, 2017
Human butyrylcholinesterase is a performant stoichiometric bioscavenger of organophosphorous nerve agents. It is either isolated from outdated plasma or functionally expressed in eukaryotic systems.
Xavier Brazzolotto, Alexandre Igert, Virginia Guillon, Gianluca Santoni, Florian Nachon   +4 more
doaj   +2 more sources

Human cerebrospinal fluid acetylcholinesterase and butyrylcholinesterase. Evidence for identity between the serum and cerebrospinal fluid butyrylcholinesterase

Clinica Chimica Acta, 1989
Human cerebrospinal fluid contained both acetylcholinesterase (EC 3.1.1.7) and butyrylcholinesterase (EC 3.1.1.8) and they were estimated in the presence of selective inhibitors.
A S Balasubramanian
exaly   +2 more sources

Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach

Lipids in Health and Disease, 2005
Background Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide sequences downloaded from NCBI ...
Sreelatha S, Madhavi AS, Apparao Allam, Nirmala G, Sridhar GR, Rani J Sudha, Vijayalakshmi P   +6 more
doaj   +2 more sources

The interaction of amiloride with acetylcholinesterase and butyrylcholinesterase

FEBS Letters, 1990
The diuretic drug amiloride was found to be a powerful inhibitor of the reaction of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with their specific choline ester substrates. The inhibition constant is in the micromolar range.
Zemach, Lucie, Lucie Zemach, Dina Segal, Shalitin, Yechiel, Yechiel Shalitin, Segal, Dina   +5 more
core   +3 more sources

The Selectivity of Butyrylcholinesterase Inhibitors Revisited

Molecules
Acetylcholinesterase (AChE) inhibitors are the primary target for single-molecule anti-Alzheimer’s disease (AD) therapeutics. Though AChE has historically been the focus of investigation for small-molecule inhibitors, interest in another cholinergic ...
Michael D. Gambardella, Yigui Wang, Jiongdong Pang   +2 more
doaj   +4 more sources