Results 11 to 20 of about 10,504 (228)

In Vitro Evaluation of Antidiabetic, Antioxidant, and Anticholinergic Properties of Different Parts of Bilberry (<i>Vaccinium myrtillus</i> L.) From the Eastern Black Sea Region, With LC/MS-MS Analysis of Their Chemical Composition in Food Applications. [PDF]

open access: yesFood Sci Nutr
This study evaluates the phytochemical composition and biological activities of wild bilberry (Vaccinium myrtillus L.) extracts. Leaf extracts showed strong antioxidant, antidiabetic, and anticholinesterase effects, highlighting their potential in managing diabetes and Alzheimer's disease.
Yuca H   +4 more
europepmc   +2 more sources

Comparison of butyrylcholinesterase and acetylcholinesterase [PDF]

open access: yesBiochemical Journal, 1989
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are compared, the first focus being on the high homologies of the molecular forms, and the homologies in protein sequences. Cholinesterases are the prototype of a new family of related serine hydrolases. Secondly, the distribution and regulation of AChE and BChE is reviewed.
Chatonnet, Arnaud, Lockridge, O.
openaire   +5 more sources

Evolution of Acetylcholinesterase and Butyrylcholinesterase in the Vertebrates: An Atypical Butyrylcholinesterase from the Medaka Oryzias latipes [PDF]

open access: goldPLoS ONE, 2011
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are thought to be the result of a gene duplication event early in vertebrate evolution. To learn more about the evolution of these enzymes, we expressed in vitro, characterized, and modeled a recombinant cholinesterase (ChE) from a teleost, the medaka Oryzias latipes.
Leo Pezzementi   +2 more
openalex   +7 more sources

Electrochemical MIP Sensor for Butyrylcholinesterase [PDF]

open access: yesPolymers, 2019
Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically relevant enzyme butyrylcholinesterase (BuChE) is presented.
Ozcelikay, Goksu   +7 more
openaire   +4 more sources

Molecular forms of butyrylcholinesterase and obesity [PDF]

open access: yesGenetics and Molecular Biology, 2010
This study compared obese (N = 134) and unobese (N = 92) male blood donors, regarding the relative intensity (RI) and activity of different molecular forms (G1, G2, G4 and G1-ALB) of butyrylcholinesterase (BChE, EC 3.1.1.8) found in plasma, thereby searching for an association between these variables with obesity and SNPs of exons 1 and 4 of the BCHE ...
Boberg, Dellyana R.   +3 more
openaire   +6 more sources

Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Caffeine is an alkaloid with a stimulant effect in the body. It can interfere in transmissions based on acetylcholine, epinephrine, norepinephrine, serotonin, dopamine and glutamate. Clinical studies indicate that it can be involved in the slowing of Alzheimer disease pathology and some other effects. The effects are not well understood. In the present
Miroslav Pohanka, Petr Dobes
openaire   +3 more sources

Butyrylcholinesterase and the cholinergic system

open access: yesNeuroscience, 2013
The cholinergic system plays important roles in neurotransmission in both the peripheral and central nervous systems. The cholinergic neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and its action terminated by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
Sultan Darvesh   +2 more
openaire   +3 more sources

The role of acetylcholinesterase and butyrylcholinesterase activity in the development of delirium in acute stroke

open access: yesCerebral Circulation - Cognition and Behavior, 2021
Aim: Our study aimed to test whether plasma acetylcholinesterase and butyrylcholinesterase enzyme activity were related to the presence and intensity of delirium in acute stroke patients.
Lara Caeiro   +5 more
doaj  

Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach

open access: yesLipids in Health and Disease, 2005
Background Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide sequences downloaded from NCBI ...
Sreelatha S   +6 more
doaj   +1 more source

Structure–activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
To discover novel scaffolds as leads against dementia, a series of δ-aryl-1,3-dienesulfonyl fluorides with α-halo, α-aryl and α-alkynyl were assayed for ChE inhibitory activity, in which compound A10 was identified as a selective BuChE inhibitor (IC50 ...
Chengyao Wu   +7 more
doaj   +1 more source

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