Results 11 to 20 of about 11,286 (211)
Wide awake under anesthesia: Scoline apnoea update [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2016 Butyrylcholinesterase (BChE) catalyses the hydrolysis of choline esters and thus deactivates muscle relaxants such as succinylcholine and mivacurium. The prolonged neuromuscular blockade following the use of succinylcholine, called scoline apnea, occurs ...
Marković Danica, Janković Radmilo J.
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Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold. [PDF]
PLoS ONE, 2018 This paper describes the synthesis and anticholinesterase potency of Cinchona-based alkaloids; ten quaternary derivatives of cinchonines and their corresponding pseudo-enantiomeric cinchonidines. The quaternization of quinuclidine moiety of each compound
Anita Bosak +5 more
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Molecules, 2021 Alzheimer’s disease (AD) is a progressive age-related neurodegenerative disease recognized as the most common form of dementia among elderly people. Due to the fact that the exact pathogenesis of AD still remains to be fully elucidated, the treatment is ...
Lucie Cahlíková +8 more
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Evaluation of derivatives of 2,3-dihydroquinazolin-4(1H)-one as inhibitors of cholinesterases and their antioxidant activity: In vitro, in silico, and kinetics studies [PDF]
Journal of the Serbian Chemical Society, 2023 In search of potent inhibitors of cholinesterase enzymes and antioxidant agents, synthetic derivatives of dihydroquinazolin-4(1H)-one (1–38) were evaluated as potential anti-Alzheimer agents through in vitro acetylcholinesterase (AChE) and ...
Babatunde Oluwatoyin +11 more
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Electrochemical MIP Sensor for Butyrylcholinesterase [PDF]
Polymers, 2019 Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically relevant enzyme butyrylcholinesterase (BuChE) is presented.
Ozcelikay, Goksu +7 more
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Butyrylcholinesterase–Protein Interactions in Human Serum [PDF]
International Journal of Molecular Sciences, 2021 Measuring various biochemical and cellular components in the blood is a routine procedure in clinical practice. Human serum contains hundreds of diverse proteins secreted from all cells and tissues in healthy and diseased states. Moreover, some serum proteins have specific strong interactions with other blood components, but most interactions are ...
Jacek Jasiecki +6 more
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Serum cholinesterases are differentially regulated in normal and dystrophin-deficient mutant mice
Frontiers in Molecular Neuroscience, 2012 The cholinesterases, acetylcholinesterase and butyrylcholinesterase (pseudocholinesterase), are abundant in the nervous system and in other tissues. The role of acetylcholinesterase in terminating transmitter action in the peripheral and central nervous ...
Andrea R. Durrant +2 more
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Clinics, 2013 OBJECTIVE: To investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels.
Liu-Xue Yang +3 more
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Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine
Molecules, 2022 Magnofluorine, a secondary metabolite commonly found in various plants, has pharmacological potential; however, its antioxidant and enzyme inhibition effects have not been investigated.
Lokman Durmaz +5 more
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Molecules, 2022 Transformations of 1-methoxymethylethynyl substituted isoquinolines triggered by terminal alkynes in alcohols were studied and new 3-benzazecine-containing compounds synthesized, such as 6-methoxymethyl-3-benzazecines incorporating an endocyclic C6–C8 ...
Alexander A. Titov +9 more
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