In Vitro Evaluation of Antidiabetic, Antioxidant, and Anticholinergic Properties of Different Parts of Bilberry (<i>Vaccinium myrtillus</i> L.) From the Eastern Black Sea Region, With LC/MS-MS Analysis of Their Chemical Composition in Food Applications. [PDF]
This study evaluates the phytochemical composition and biological activities of wild bilberry (Vaccinium myrtillus L.) extracts. Leaf extracts showed strong antioxidant, antidiabetic, and anticholinesterase effects, highlighting their potential in managing diabetes and Alzheimer's disease.
Yuca H+4 more
europepmc +2 more sources
Comparison of butyrylcholinesterase and acetylcholinesterase [PDF]
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are compared, the first focus being on the high homologies of the molecular forms, and the homologies in protein sequences. Cholinesterases are the prototype of a new family of related serine hydrolases. Secondly, the distribution and regulation of AChE and BChE is reviewed.
Chatonnet, Arnaud, Lockridge, O.
openaire +5 more sources
Evolution of Acetylcholinesterase and Butyrylcholinesterase in the Vertebrates: An Atypical Butyrylcholinesterase from the Medaka Oryzias latipes [PDF]
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are thought to be the result of a gene duplication event early in vertebrate evolution. To learn more about the evolution of these enzymes, we expressed in vitro, characterized, and modeled a recombinant cholinesterase (ChE) from a teleost, the medaka Oryzias latipes.
Leo Pezzementi+2 more
openalex +7 more sources
Electrochemical MIP Sensor for Butyrylcholinesterase [PDF]
Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically relevant enzyme butyrylcholinesterase (BuChE) is presented.
Ozcelikay, Goksu+7 more
openaire +4 more sources
Molecular forms of butyrylcholinesterase and obesity [PDF]
This study compared obese (N = 134) and unobese (N = 92) male blood donors, regarding the relative intensity (RI) and activity of different molecular forms (G1, G2, G4 and G1-ALB) of butyrylcholinesterase (BChE, EC 3.1.1.8) found in plasma, thereby searching for an association between these variables with obesity and SNPs of exons 1 and 4 of the BCHE ...
Boberg, Dellyana R.+3 more
openaire +6 more sources
Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase [PDF]
Caffeine is an alkaloid with a stimulant effect in the body. It can interfere in transmissions based on acetylcholine, epinephrine, norepinephrine, serotonin, dopamine and glutamate. Clinical studies indicate that it can be involved in the slowing of Alzheimer disease pathology and some other effects. The effects are not well understood. In the present
Miroslav Pohanka, Petr Dobes
openaire +3 more sources
Butyrylcholinesterase and the cholinergic system
The cholinergic system plays important roles in neurotransmission in both the peripheral and central nervous systems. The cholinergic neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and its action terminated by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
Sultan Darvesh+2 more
openaire +3 more sources
Aim: Our study aimed to test whether plasma acetylcholinesterase and butyrylcholinesterase enzyme activity were related to the presence and intensity of delirium in acute stroke patients.
Lara Caeiro+5 more
doaj
Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach
Background Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide sequences downloaded from NCBI ...
Sreelatha S+6 more
doaj +1 more source
To discover novel scaffolds as leads against dementia, a series of δ-aryl-1,3-dienesulfonyl fluorides with α-halo, α-aryl and α-alkynyl were assayed for ChE inhibitory activity, in which compound A10 was identified as a selective BuChE inhibitor (IC50 ...
Chengyao Wu+7 more
doaj +1 more source