Results 31 to 40 of about 10,504 (228)
Rambam Maimonides Medical Journal, 2010 In Alzheimer’s disease (AD), premature demise of acetylcholine-producing neurons and the consequent decline of cholinergic transmission associate with the prominent cognitive impairments of affected individuals.
Amit Berson, Hermona Soreq
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Chemico-Biological Interactions, 2016 Five mouse anti-human butyrylcholinesterase (BChE) monoclonal antibodies bind tightly to native human BChE with nanomolar dissociation constants. Pairing analysis in the Octet system identified the monoclonal antibodies that bind to overlapping and independent epitopes on human BChE.
Peng, Hong +7 more
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Alzheimer’s Disease Pharmacotherapy in Relation to Cholinergic System Involvement
Biomolecules, 2019 Alzheimer’s disease, a major and increasing global health challenge, is an irreversible, progressive form of dementia, associated with an ongoing decline of brain functioning.
Gabriela Dumitrita Stanciu +7 more
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Sensors, 2019 This study explores the use of a butyrylcholinesterase (BChE)-based, reversible reaction biosensor using screen-printed electrodes (SPEs) having a smaller working surface area than the single-use electrodes previously studied.
Christopher Edwards +4 more
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The interaction of amiloride with acetylcholinesterase and butyrylcholinesterase
FEBS Letters, 1990 The diuretic drug amiloride was found to be a powerful inhibitor of the reaction of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with their specific choline ester substrates. The inhibition constant is in the micromolar range. On the other hand, when added to a mixture of cholinesterase (AChE and BChE) and neutral substrates, amiloride,
Lucie Zemach +2 more
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Sensors, 2015 Smartphones are popular devices frequently equipped with sensitive sensors and great computational ability. Despite the widespread availability of smartphones, practical uses in analytical chemistry are limited, though some papers have proposed promising
Miroslav Pohanka
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Advanced Biomedical Research, 2023 Background: The long-term use of pesticides can cause harmful consequences to both human health and the environment. In the present research, we aimed to compare biochemical, hematological, and plasmatic measurements of butyrylcholinesterase (BChE ...
Hasnaa Sine +3 more
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Benzoylcholine, Indole-3-acetic And Human Serum Butyrylcholinesterase Interactions [PDF]
Türk Biyokimya Dergisi, 2006 In this study we studied the kinetic interaction of indole-3- acetic acid with human serum butyrylcholinesterase. Butyrylcholinesterase was purified from human serum and the benzoylcholine kinetics was analyzed.
Ebru Bodur,, A. Neşe Çokuğraş
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Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine
Molecules, 2022 Magnofluorine, a secondary metabolite commonly found in various plants, has pharmacological potential; however, its antioxidant and enzyme inhibition effects have not been investigated.
Lokman Durmaz +5 more
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Characterization of butyrylcholinesterase in bovine serum
Chemico-Biological Interactions, 2017 Human butyrylcholinesterase (HuBChE) protects from nerve agent toxicity. Our goal was to determine whether bovine serum could be used as a source of BChE. Bovine BChE (BoBChE) was immunopurified from 100 mL fetal bovine serum (FBS) or 380 mL adult bovine serum by binding to immobilized monoclonal mAb2.
Lawrence M. Schopfer +5 more
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