Results 71 to 80 of about 10,504 (228)

Decoding Chemical Profiles, Biological Functions, and Medicinal Properties of Liquidambar orientalis Extracts Through Molecular Modeling and Bioinformatic Methods

Food Frontiers, Volume 6, Issue 3, Page 1376-1408, May 2025.
In this study, we showed the potential therapeutical properties, namely, antioxidant, antimicrobial, enzyme inhibitory, and antitumor, of Liquidambar orientalis extracts from its aerial parts using methanol, ethyl acetate, and water. The methanolic extract of exhibited the highest phenolic and flavonoid content, demonstrating superior antioxidant ...
Mehmet Cengiz Baloglu, Lutfiye Yildiz Ozer, Buket Pirci, Yasemin Celik Altunoglu, Sanam Iram Soomro, Gokhan Zengin, Mehmet Veysi Cetiz, Simone Carradori, Zoltán Cziáky, József Jekő   +9 more
wiley   +1 more source

Ultrasound‐Assisted Extraction of Bioactive Compounds From Black Pine (Pinus nigra) Bark: Optimization and Evaluation of Their In Vitro Bioactivities

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
Black pine bark extract holds significant potential as a versatile bioactive ingredient for the development of functional foods. Its antioxidant, antidiabetic, and health promoting properties make it valuable for enhancing the nutritional and functional quality of food products. Its incorporation into foods can also enhance their nutritional properties 
Kubra Feyza Erol, Gozde Kutlu, Necattin Cihat Icyer, Fatih Tornuk   +3 more
wiley   +1 more source

Treating Cocaine Addiction, Obesity, and Emotional Disorders by Viral Gene Transfer of Butyrylcholinesterase

Frontiers in Pharmacology, 2018
Butyrylcholinesterase (BChE), a plasma enzyme that hydrolyses the neurotransmitter, acetylcholine relatively well, with far lower efficiency than acetylcholinesterase (AChE) but with the capability to degrade a broad range of bioactive esters.
Stephen Brimijoin, Yang Gao, Liyi Geng, Vicky P. Chen   +3 more
doaj   +1 more source

Butyrylcholinesterase Protein Ends in the Pathogenesis of Alzheimer’s Disease—Could BCHE Genotyping Be Helpful in Alzheimer’s Therapy?

Biomolecules, 2019
Late-onset Alzheimer’s disease (AD) is clinically characterized by a progressive decline of memory and other cognitive functions leading to the loss of the ability to perform everyday activities.
Jacek Jasiecki, Bartosz Wasąg
doaj   +1 more source

Opening New Roads for Multi‐Directional Functional Applications Through In Vitro Chemical and Biological Analysis of Zoegea leptaurea L. Extracts

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
Zoegea leptaurea is a promising source of bioactive compounds and warrants further investigation for its potential role in the treatment of global health problems. ABSTRACT Zoegea leptaurea L. has been traditionally used to treat digestive issues, headaches, and skin diseases.
Sakina Yagi, Giovanni Caprioli, Gabriele Rocchetti, Filomena Nazzaro, Florinda Fratianni, Francesca Coppola, Ozgur Yuksekdag, Ismail Koyuncu, Laura Acquaticci, Simone Angeloni, Mehmet Maruf Balos, Ulku Yerebasan, Gokhan Zengin   +12 more
wiley   +1 more source

Therapeutic Delivery of Butyrylcholinesterase by Brain-Wide Viral Gene Transfer to Mice

Molecules, 2017
Recent research shows that butyrylcholinesterase (BChE) is not simply a liver enzyme that detoxifies bioactive esters in food and medications. In fact, in pursuing other goals, we recently found that it has an equally important role in regulating the ...
Yang Gao, Liyi Geng, Vicky Ping Chen, Stephen Brimijoin   +3 more
doaj   +1 more source

Phenolic Content, Antioxidant Capacity, and Therapeutic Potential of Mango (Mangifera indica L.) Leaves

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
The ethanol extract of Mangifera indica L. leaves was evaluated for its phenolic profile (LC–MS/MS), antioxidant capacity (DPPH, ABTS, FRAP, CUPRAC), and enzyme inhibition activities (AChE, BChE, α‐glucosidase). The phenolic compounds exhibiting notable antioxidant activity, the extract shows enzyme inhibitory effects, suggesting it may hold ...
Mesut Işık, Emrah Dikici, Sevgi Altın, Cemalettin Alp, Kevser Kübra Kırboğa, Ekrem Köksal, Şükrü Beydemir   +6 more
wiley   +1 more source

Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase

Biomolecules, 2020
Thirteen known (1–12 and 16) and three previously undescribed Amaryllidaceae alkaloids of belladine structural type, named carltonine A-C (13–15), were isolated from bulbs of Narcissus pseudonarcissus cv.
Abdullah Al Mamun, Jana Maříková, Daniela Hulcová, Jiří Janoušek, Marcela Šafratová, Lucie Nováková, Tomáš Kučera, Martina Hrabinová, Jiří Kuneš, Jan Korábečný, Lucie Cahlíková   +10 more
doaj   +1 more source

Diagnosis of Inherited Metabolic Disease in Older Patients: A Systematic Literature Review

Journal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.
ABSTRACT Inherited metabolic diseases (IMDs) are genetic disorders that disrupt biochemical processes in the human body, due to pathogenic variants in genes encoding enzymes or transporters. While IMDs are mostly diagnosed in infancy or childhood, there is an increasing number of diagnoses in adult patients.
Maria‐Rita Moio, Julia Cordeiro Milke, Yannick Moutapam‐Ngamby‐Adriaansen, Arthur Minas Alberti, Marie Gernay, Eduardo Schütz, Ida Vanessa Doederlein Schwartz, François Maillot   +7 more
wiley   +1 more source

Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine

Molecules, 2020
Bacterial transglutaminase was used to label human plasma proteins with fluorescent tags. Protein lysines were modified with dansyl-epsilon-aminohexyl-Gln-Gln-Ile-Val-OH (dansylQQIV), while protein glutamines were modified with dansyl cadaverine. Labeled
Lawrence M. Schopfer, Oksana Lockridge
doaj   +1 more source