Results 41 to 50 of about 4,912 (164)
Fast dehydration reduces bundle sheath conductance in C4 maize and sorghum
New Phytologist, Volume 244, Issue 6, Page 2197-2209, December 2024.Summary In the face of anthropogenic warming, drought poses an escalating threat to food production. C4 plants offer promise in addressing this threat. C4 leaves operate a biochemical CO2 concentrating mechanism that exchanges metabolites between two partially isolated compartments (mesophyll and bundle sheath), which confers high‐productivity ...
Chandra Bellasio +3 more
wiley +1 more source
miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors
Molecular Oncology, 2019 Aberrant expression of the pluripotency factor OCT4A in embryonal tumors of the central nervous system (CNS) is a key factor that contributes to tumor aggressiveness and correlates with poor patient survival.
Carolini Kaid +5 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2021 Objetivos: Dados recentes têm demonstrado que o uso do Ibrutinibe pode ser uma medida terapêutica eficaz contra a doença do enxerto contra o hospedeiro crônica (DECHc) refratária a corticoides.
AES Carvalho +4 more
doaj +1 more source
H218O vapour labelling reveals evidence of radial Péclet effects, but in not all leaves
New Phytologist, Volume 244, Issue 4, Page 1263-1274, November 2024.Summary Contradictory evidence exists regarding the relevance of Péclet‐like gradients in leaf water isotopes, making it difficult to accurately predict variation in isotope composition. Here, we use H218O vapour labelling to directly test whether leaf water isotopes diffuse back into the xylem to be carried forward to more distal leaf portions ...
Margaret M. Barbour +2 more
wiley +1 more source
Plasmodesmata and intercellular molecular traffic control
New Phytologist, Volume 243, Issue 1, Page 32-47, July 2024.Summary Plasmodesmata are plasma membrane‐lined connections that join plant cells to their neighbours, establishing an intercellular cytoplasmic continuum through which molecules can travel between cells, tissues, and organs. As plasmodesmata connect almost all cells in plants, their molecular traffic carries information and resources across a range of
Estee E. Tee, Christine Faulkner
wiley +1 more source
Understanding rare variant contributions to autism: lessons from dystrophin-deficient model
npj Genomic MedicineDuchenne and Becker Muscular Dystrophy are dystrophinopathies with a prevalence of 1:5000–6000 males, caused by pathogenic variants in DMD. These conditions are often accompanied by neurodevelopmental disorders (NDDs) like autism (ASD; ~20%) and ...
Claudia Ismania Samogy Costa +15 more
doaj +1 more source
Molecular and functional anticancer effects of GLP/G9a inhibition by UNC0646 in MeWo melanoma cells
HeliyonIn recent years, histone methyltransferases (HMTs) have emerged as important therapeutic targets in cancer due to their oncogenic role. Herein, we used the GLP/G9a inhibitor UNC0646 to assess whether the inhibition of such HMTs could induce cell death in
Luma Dayane de Carvalho Filiú-Braga +4 more
doaj +1 more source
Veterinary Dermatology, Volume 35, Issue 3, Page 325-336, June 2024.Background – Norway spruce (Picea abies) resin‐based products are used in human medicine. A resin‐based otic rinse also could be useful in supportive care of canine otitis externa (COE), yet information on its antimicrobial effect against canine pathogens or ototoxicity is lacking.
Elina Aimo‐Koivisto +5 more
wiley +1 more source
Functional traits of fossil plants
New Phytologist, Volume 242, Issue 2, Page 392-423, April 2024.Summary A minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits ...
Jennifer C. McElwain +14 more
wiley +1 more source
Translational Psychiatry, 2022 Oligogenic inheritance of autism spectrum disorder (ASD) has been supported by several studies. However, little is known about how the risk variants interact and converge on causative neurobiological pathways.
André Luíz Teles e Silva +12 more
doaj +1 more source