Results 11 to 20 of about 17,188 (276)
c-di-GMP Inhibits Early Sporulation in Clostridioides difficile [PDF]
mSphere, 2021 The formation of dormant spores is essential for the anaerobic pathogen Clostridioides difficile to survive outside the host gastrointestinal tract. The regulatory pathways and environmental signals that initiate C.
Adrianne N. Edwards +4 more
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Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection [PDF]
Frontiers in Microbiology, 2018 Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body.
Guohui Xiao +9 more
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Polymorphism of the Signaling Molecule c-di-GMP [PDF]
Journal of the American Chemical Society, 2006 Using UV, CD, and NMR, we demonstrate that the important bacterial signaling molecule involved in biofilm formation, cyclic diguanosine monophosphate (c-di-GMP), exists as a mixture of five different but related structures in an equilibrium that is sensitive both to its concentration and to the metal present. At the lower concentrations used for UV and
Zhaoying Zhang +3 more
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Multiple activities of c-di-GMP in Pseudomonas aeruginosa [PDF]
Nucleic Acids Symposium Series, 2009 Survival strategies of many bacterial pathogens, including Pseudomonas aeruginosa, are linked to their ability to form surface associated communities called biofilms. The biofilm life style allows these organisms to persist in various tissues, avoid clearance by innate host defences and significantly enhanced their resistance to antibiotics.
Stephen Lory +2 more
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Bacterial c-di-GMP triggers metamorphosis of mussel larvae through a STING receptor [PDF]
npj Biofilms and MicrobiomesBacteria induced metamorphosis observed in nearly all marine invertebrates. However, the mechanism of bacteria regulating the larvae-juvenile metamorphosis remains unknown.
Xiao-Meng Hu +6 more
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A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa [PDF]
Nature CommunicationsCyclic dimeric guanosine monophosphate (c-di-GMP) serves as a bacterial second messenger that modulates various processes including biofilm formation, motility, and host-microbe symbiosis.
Xueliang Zhan +8 more
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Visualization of c-di-GMP in multicellular Dictyostelium stages. [PDF]
Front Cell Dev Biol, 2023 The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes. Dictyostelium cells undergo a transition from a unicellular to a multicellular state, ultimately forming a stalk and spores.
Ide H, Hayashida Y, Morimoto YV.
europepmc +4 more sources
Polarity of c-di-GMP synthesis and degradation. [PDF]
Microlife, 2023 AbstractThe bacterial cell pole has long been recognized as a defined compartment for enzymatic activities that are important or even vital for the cell. Polarity of diguanylate cyclases and phosphodiesterases, enzymes that synthesize and degrade the second messenger c-di-GMP, has now been demonstrated for several bacterial systems.
Kreiling V, Thormann KM.
europepmc +3 more sources
OpaR Controls the Metabolism of c-di-GMP in Vibrio parahaemolyticus [PDF]
Frontiers in Microbiology, 2021 Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis worldwide, has a strong ability to form biofilms on surfaces. Quorum sensing (QS) is a process widely used by bacteria to communicate with each other and control gene expression via the secretion and detection of autoinducers.
Yiquan Zhang +12 more
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Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle. [PDF]
PLoS Genetics, 2013 Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Sören Abel +6 more
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