Results 1 to 10 of about 157,346 (209)

The multiple roles of C-type lectin receptors in cancer [PDF]

Frontiers in Oncology, 2023
C-type lectin receptors are a family of immune response receptors that can bind with a broad repertoire of ligands. It can function as innative immune receptors to surveillance bacteria, fungi, and virus invasions.
Qiao Li
doaj   +4 more sources

C-Type Lectin Receptors in Asthma [PDF]

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled ...
Sabelo Hadebe, Sabelo Hadebe, Frank Brombacher, Frank Brombacher, Gordon D. Brown, Gordon D. Brown   +5 more
doaj   +5 more sources

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia

Haematologica, 2010
Background C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells.
Xiaoxian Zhao, Shweta Singh, Cecile Pardoux, Jingsong Zhao, Eric D. Hsi, Arie Abo, Wouter Korver   +6 more
doaj   +3 more sources

C-type lectin-like receptor 2: roles and drug target [PDF]

Thrombosis Journal
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively.
Lan Sun, Zhe Wang, Zhiyan Liu, Guangyan Mu, Yimin Cui, Qian Xiang   +5 more
doaj   +2 more sources

Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?

Insects, 2021
Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen, Kristof De Schutter, Els J. M. Van Damme, Guy Smagghe   +3 more
doaj   +1 more source

Association of circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 with inflammatory markers and urinary albumin excretion in patients with type 2 diabetes

SAGE Open Medicine, 2021
Objectives: The main purpose of the study was to study the association between circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels and various markers, including inflammatory markers such as high-sensitivity C-reactive ...
Kohzo Takebayashi, Tatsuhiko Suzuki, Mototaka Yamauchi, Kenji Hara, Takafumi Tsuchiya, Toshihiko Inukai, Koshi Hashimoto   +6 more
doaj   +1 more source

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. [PDF]

PLoS ONE, 2013
Mannose-binding lectin (MBL) is a key soluble effector of the innate immune system that recognizes pathogen-specific surface glycans. Surprisingly, low-producing MBL genetic variants that may predispose children and immunocompromised individuals to ...
Matthew Brudner, Marshall Karpel, Calli Lear, Li Chen, L Michael Yantosca, Corinne Scully, Ashish Sarraju, Anna Sokolovska, M Reza Zariffard, Damon P Eisen, Bruce A Mungall, Darrell N Kotton, Amel Omari, I-Chueh Huang, Michael Farzan, Kazue Takahashi, Lynda Stuart, Gregory L Stahl, Alan B Ezekowitz, Gregory T Spear, Gene G Olinger, Emmett V Schmidt, Ian C Michelow   +22 more
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Lectins with Potential for Anti-Cancer Therapy

Molecules, 2015
This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau, Xiuli Dan, Charlene Cheuk Wing Ng, Tzi Bun Ng   +3 more
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MCL and mincle: C-type lectin receptors that sense damaged self and pathogen associated molecular patterns

Frontiers in Immunology, 2014
MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Mark B Richardson, Spencer J Williams
doaj   +1 more source

Key thermally dimorphic fungal pathogens: shaping host immunity

Open Biology, 2022
Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft, Lucian Duvenage, J. Claire Hoving   +2 more
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