The diverse roles of C-type lectin-like receptors in immunity [PDF]
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
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Signaling C-type lectin receptors in antimycobacterial immunity. [PDF]
PLoS Pathogens, 2017 Mohlopheni J Marakalala, Hlumani Ndlovu
doaj +3 more sources
The C-type lectin of the aggrecan G3 domain activates complement. [PDF]
PLoS ONE, 2013 Excessive complement activation contributes to joint diseases such as rheumatoid arthritis and osteoarthritis during which cartilage proteins are fragmented and released into the synovial fluid.
Camilla Melin Fürst +5 more
doaj +3 more sources
Syk-coupled C-type lectins in immunity [PDF]
Trends in Immunology, 2011 The Syk-coupled C-type lectin receptor Dectin-1 was the first non-Toll like receptor described that could mediate its own intracellular signalling. It was initially identified as important for the innate recognition of and response to fungal pathogens but later studies revealed that it is also involved in triggering adaptive immune responses.
Ann M. Kerrigan, Gordon D. Brown
openalex +3 more sources
The distribution of lectins across the phylum Nematoda : a genome-wide search [PDF]
, 2017 Nematodes are a very diverse phylum that has adapted to nearly every ecosystem. They have developed specialized lifestyles, dividing the phylum into free-living, animal, and plant parasitic species. Their sheer abundance in numbers and presence in nearly
Bauters, Lander +2 more
core +9 more sources
BACL is a novel brain-associated, non-NKC-encoded mammalian C-type lectin-like receptor of the CLEC2 family [PDF]
, 2013 Natural Killer Gene Complex (NKC)–encoded C-type lectin-like receptors (CTLRs) are expressed on various immune cells including T cells, NK cells and myeloid cells and thereby contribute to the orchestration of cellular immune responses.
Lysenko, Olga +3 more
core +7 more sources
Haematologica, 2010 Background C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells.
Xiaoxian Zhao +6 more
doaj +1 more source
Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?
Insects, 2021 Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen +3 more
doaj +1 more source
High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]
, 2011 Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Ahmed +54 more
core +1 more source
The Rosetteless gene controls development in the choanoflagellate S. rosetta. [PDF]
, 2014 The origin of animal multicellularity may be reconstructed by comparing animals with one of their closest living relatives, the choanoflagellate Salpingoeca rosetta.
Greaney, Allison J +3 more
core +1 more source