Results 31 to 40 of about 243,058 (345)
How C-type lectins detect pathogens. [PDF]
Glycosylation of proteins has proven extremely important in a variety of cellular processes, including enzyme trafficking, tissue homing and immune functions. In the past decade, increasing interest in carbohydrate-mediated mechanisms has led to the identification of novel carbohydrate-recognizing receptors expressed on cells of the immune system ...
Cambi, A., Koopman, M., Figdor, C.G.
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Objectives: The main purpose of the study was to study the association between circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels and various markers, including inflammatory markers such as high-sensitivity C-reactive ...
Kohzo Takebayashi +6 more
doaj +1 more source
Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Akira +39 more
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Lectins with Potential for Anti-Cancer Therapy
This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau +3 more
doaj +1 more source
C-type lectins and phagocytosis
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
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MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Mark B Richardson, Spencer J Williams
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Key thermally dimorphic fungal pathogens: shaping host immunity
Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft +2 more
doaj +1 more source
Analysis of part of the chicken Rfp-Y region reveals two novel lectin genes, the first complete genomic sequence of a class I α-chain gene, a truncated class II β-chain gene, and a large CR1 repeat [PDF]
The Rfp-Y region lies on the same microchromosome as the B-F/B-L region of the B complex, yet in contrast to the latter it is poorly characterised. To date it has been shown to contain at least two class I alpha-chain ( Y-F) genes, a class II B-chain ...
Afanassieff +55 more
core +1 more source
Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY [PDF]
Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart of mammalian FcRn (a major histocompatibility complex homolog), transfers IgY across the avian yolk sac, and ...
BENNETT +22 more
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Evolution and Immune Function of Fish Lectins [PDF]
Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as ...
Ahmad +95 more
core +1 more source

