Results 181 to 190 of about 85,647 (228)

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Myeloid C-type lectin receptors that recognize fungal mannans interact with <i>Pneumocystis</i> organisms and major surface glycoprotein. [PDF]

J Med Microbiol, 2019
Kottom TJ, Hebrink DM, Monteiro JT, Lepenies B, Carmona EM, Wuethrich M, Santo Dias LD, Limper AH.   +7 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Genetic polymorphisms of C-type lectin receptors in Behcet's disease in a Chinese Han population. [PDF]

Sci Rep, 2017
Yang Y, Tan H, Deng B, Yu H, Su G, Hu J, Cao Q, Yuan G, Kijlstra A, Yang P.   +9 more
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Paired C-type lectin receptors mediate specific recognition of divergent oomycete pathogens in C. elegans

Liu K, Grover M, Trusch F, Vagena-Pantoula C, Ippolito D, Barkoulas M.   +5 more
europepmc   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

α‐1,3‐Glucan Is Required for Cell Wall Integrity and Full Virulence of Colletotrichum graminicola, but Not for Evasion of PAMP‐Triggered Immunity

Molecular Microbiology, EarlyView.
Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase, Lala Aliyeva‐Schnorr, Michael Melzer, Maria Ott, Julia Haufe, Matthias Menzel, Timo Engelsdorf, Christiane Rohrbach, Alan de Oliveira Silva, Lars M. Voll, Alexander S. Mickel, Maximilian Groß, Mamoru Wakayama, Holger B. Deising   +13 more
wiley   +1 more source

Osteolectin/CLEC11A‐Related Signaling Molecules in Periodontitis and Peri‐Implantitis

Oral Diseases, EarlyView.
ABSTRACT Objective Periodontal and peri‐implant tissues differ histologically and biomechanically, which may be reflected in local osteogenic and mechanosensitive signaling. This exploratory cross‐sectional study aimed to compare expression profiles of Osteolectin (CLEC11A) and related signaling molecules across periodontal health, peri‐implant health,
Gözde Işıker Kara, Feyzanur Caldiran, Hatice Balci Yuce, Busenur Sahin, Ercan Cacan   +4 more
wiley   +1 more source