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Structural Aspects of C-Type Lectin Receptors
2016Numerous structural analyses (X-ray crystallography and NMR) of C-type lectin receptors (CLRs) have been performed, because CLRs are not only attractive as important molecules in immunity and infectious diseases but also as drug targets. In CLRs, high amino acid sequence similarity exists in the extracellular carbohydrate recognition domains (CRDs ...
Atsushi Furukawa +4 more
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C-type Lectin Receptor: Old Friend and New Player
Medicinal Chemistry, 2017During the last two decades, C-type lectin receptors (CLRs) have been demonstrated to play key roles in initiating the host immune response against fungal infection. It is well established that CLRs, such as Dectin-1, Dectin-2, Dectin-3 and Mincle recognize the cell wall component from the infected microorganisms by using their carbohydrate recognition
Hai, Hou +5 more
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Screening for Ligands of C-Type Lectin-Like Receptors
2011In order to execute their immune functions, leukocytes interact with a broad range of cell types through cell surface receptors, such as those of the immunoglobulin and C-type lectin families, or indirectly through soluble factors. The characterization of activating and inhibitory counterparts of NK cell receptors on myeloid cells, as well as the ...
Elwira, Pyż, Gordon D, Brown
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C-Type Lectins: Multifaceted Receptors in Phagocyte Biology
2014This chapter focuses on those members of the C-type lectin family that contain a classical carbohydrate recognition domain (CRD) and are expressed and functional on phagocytic cells of the immune system, such as neutrophils, dendritic cells (DCs), and macrophages.
Alessandra Cambi, Carl G. Figdor
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C-type lectin receptors (CLRs)
Reactome - a curated knowledgebase of biological pathways, 2015openaire +1 more source
C-Type Lectin-Like Receptor 2 (CLEC-2)
2016C-type lectin-like receptor 2 (CLEC-2) has been identified as a receptor for a platelet-activating snake venom, rhodocytin. CLEC-2 elicits powerful platelet activation signals in a manner dependent on Src, Syk kinases, and phospholipase Cγ2, similar to the collagen receptor glycoprotein (GP) VI/FcRγ-chain complex.
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Transmembrane C-type lectin receptors in immunity
Вестник Сыктывкарского университета. Серия 2: Биология. Геология. Химия. Экология, 2021openaire +1 more source
C-Type Lectin Receptors in Antimicrobial Immunity
2016Organized by Department of Medicine, the University of Hong Kong ; Sponsored by the Croucher ...
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C-type lectin receptors in the control of T helper cell differentiation
Nature Reviews Immunology, 2016Sonja Gringhuis
exaly