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C-type lectins belong to a widely conserved family of lectins characterized in Metazoa. They show important functional diversity and immune implications, mainly as pathogen recognition receptors.
Amaro Saco +3 more
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Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?
Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen +3 more
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Information transfer in mammalian glycan-based communication
Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger +6 more
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C-Type Lectin Receptors in Asthma [PDF]
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe +5 more
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How C-type lectins detect pathogens. [PDF]
Glycosylation of proteins has proven extremely important in a variety of cellular processes, including enzyme trafficking, tissue homing and immune functions. In the past decade, increasing interest in carbohydrate-mediated mechanisms has led to the identification of novel carbohydrate-recognizing receptors expressed on cells of the immune system ...
Cambi, A., Koopman, M., Figdor, C.G.
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The immune role of C-type lectins in molluscs [PDF]
The phylum Mollusca is one of the largest and most important group in the animal kingdom. Recently, interest in molluscan immunity has increased due to their importance in worldwide aquaculture, their role in aquatic environmental science and their ...
L Wang, L Wang, M Huang, H Zhang, L Song
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C-type lectins and phagocytosis
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
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Lectins with Anti-HIV Activity: A Review
Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity.
Ouafae Akkouh +7 more
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Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin
The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure.
Emily Gage +4 more
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Immune characterization and expression analysis of a C-type lectin from Pinctada fucata martensii
C-type lectins are involved in nonself-recognition and pathogen clearance, and play an important role in innate immunity. Pinctada fucata martensii, which is an important shellfish in the pearl industry, is being attacked by pathogenic microorganisms ...
Zhijie Guo +5 more
doaj +1 more source

