Results 11 to 20 of about 18,984,511 (231)

Laboratory diagnostic methods for clostridioides difficile infection [PDF]

One Health & Risk Management, 2023
Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C.
Anastasia ALEXANDROV
doaj   +1 more source

Development and characterisation of an in vitro human gut model to study the biofilm mode of growth of clostridium difficile and the indigenous gut microbiota [PDF]

, 2013
Clostridium difficile infection (CDI) is associated with significant patient morbidity, mortality and financial burden. Until recently, antimicrobial treatment options were limited to metronidazole and vancomycin, but both agents are associated with ...
Crowther, Grace
core   +6 more sources

Dietary-based gut flora modulation against Clostridium difficile onset [PDF]

, 2007
Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Tuohy, K.M., Gougoulias, C., Gibson, G.R.   +2 more
core   +9 more sources

Aerial dissemination of Clostridium difficile spores [PDF]

, 2008
YesClostridium difficile-associated diarrhoea (CDAD) is a frequently occurring healthcare-associated infection, which is responsible for significant morbidity and mortality amongst elderly patients in healthcare facilities. Environmental contamination is
Sleigh, P.A., Snelling, Anna M., Beggs, Clive B., Smith, Caroline F., Kerr, Kevin G., Banfield, Kathleen R., Roberts, K.   +6 more
core   +5 more sources

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. [PDF]

, 2012
Relapsing C. difficile disease in humans is linked to a pathological imbalance within the intestinal microbiota, termed dysbiosis, which remains poorly understood. We show that mice infected with epidemic C.
Parkhill Julian, Duncan Sylvia H., Deakin, Laura J., Thomas R. Connor (125272), Schreiber Fernanda, Brandt, Cordelia, Pickard Derek J., Flint, Harry J, Harry J. Flint (125298), Parkhill, J, Flint, Harry James, Trevor D. Lawley (125265), Simon Clare, Roland Rad (125284), David Goulding (125280), Julian Parkhill (30393), Claire Raisen (125275), Schreiber, F, Clare Simon, Taane G Clark, Deakin Laura J., Connor Thomas R., Taane G. Clark (106263), Clark, Taane G., Gordon Dougan, Duncan, SH, Sylvia H. Duncan (125296), Stares, Mark D., Raisen Claire, Roland Rad, Trevor D Lawley, Rad, Roland, Derek J. Pickard (125293), Sylvia H Duncan, Walker Alan W., Harry J Flint, Goulding David, Rad, R, Derek J Pickard, Deakin, LJ, Schreiber, Fernanda, Clark, Taane G, Clark, TG, Rad Roland, Walker, Alan W, Flint Harry J., Goulding, David, Alan W. Walker (50247), Raisen, C, Stares, MD, Pickard, Derek J, Flint, Harry J., Lawley, Trevor D, Deakin, Laura J, Connor, Thomas R, Claire Raisen, Brandt, C, Walker, AW, Mark D Stares, Walker, Alan W., Duncan, Sylvia H, Dougan Gordon, Connor, Thomas Richard, Clare, Simon, Pickard, Derek J., Laura J Deakin, Fernanda Schreiber, Fernanda Schreiber (85280), Lawley, TD, Clare, S, Julian Parkhill, Alan W Walker, David Goulding, Lawley, Trevor D., Raisen, Claire, Mark D. Stares (125271), Cordelia Brandt (125287), Laura J. Deakin (125290), Brandt Cordelia, Dougan, Gordon, Pickard, DJ, Duncan, Sylvia H., Parkhill, Julian, Simon Clare (125268), Clark Taane G., Flint, HJ, Gordon Dougan (30395), Thomas R Connor, Stares Mark D., Stares, Mark D, Goulding, D, Cordelia Brandt, Connor, TR, Dougan, G, Lawley Trevor D.   +94 more
core   +1 more source

Emergence and global spread of epidemic healthcare-associated clostridium difficile [PDF]

, 2012
Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the leading cause of antibiotic-associated diarrhea worldwide. However, the key events in evolutionary history leading to its emergence and the subsequent patterns of global ...
Hawkey, P.r, Brazier, Jon, Martin, Melissa J, Fairley, Derek, Brown, D., Kim, H.J., Kuijper, Ed, Kato, Haru, Coia, JE, Kathleen B Bamford, Tse Hsien Koh, Kim, HJ, He, M., Wren, B.W., Miyajima, Fabio, Riley, Tom, Brazier, J. S., Kato, H., Harris, Simon R, D'Arc, S., Butt, E., Nick M Brown, Gerding, D, Martin, M.J., Wren, BW, Paul Roberts, Douce, G, Pirmohamed, M, Munir Pirmohamed, Louise Ellison, Songer, Glen, Songer, G, Coia, John E., He, M, Brendan W Wren, Douce, Gill, Kuijper, E., Sharon J Peacock, Pickard, Derek J, Butt, Emma, Mark Wilcox, Lawley, Trevor D, Dale Gerding, Wren, Brendan W, Songer, G., Senoh, Mitsutoshi, Haru Kato, Mitsutoshi Senoh, D'Arc, S, Hee Jung Kim, Pirmohamed, M., Connor, Thomas Richard, Ellison, Louise, Brown, Nick M, Wilcox, Mark, Miyajima, F, Pickard, Derek J., Harris, S.R., Roberts, Paul, Koh, Tse Hsien, Melissa J Martin, Julian Parkhill, Hawkey, P., Louie, T., Bamford, KB, Coia, J., Dougan, Gordon, Coia, John E, Parkhill, Julian, Hawkey, P, Ed Kuijper, Bamford, Kathleen B., Thomas R Connor, Gill Douce, Glen Songer, Pickard, D.J., Simon R Harris, Tom Louie, Derek Fairley, Fairley, D, Miyajima, F., Wilcox, M, Parkhill, J, Michell, S., Tom Riley, Louie, Tom, Harris, Simon R., Louie, T, Lawley, T.D., Bamford, K.B., He, Miao, Gerding, Dale, Connor, T.R., Peacock, Sharon J., Kuijper, E, Butt, E, Peacock, SJ, Brown, Derek, Senoh, M., Gordon Dougan, Pirmohamed, Munir, Gerding, D., Ellison, L, Peter Hawkey, Koh, T.H., Harris, SR, Brazier, J., Wilcox, M., Trevor D Lawley, Coia, J.E., Emma Butt, Ellison, L., Peacock, Sharon J, Brown, NM, Michell, S, Derek Brown, Derek J Pickard, Brown, Nick M., 김희정, Martin, MJ, Peacock, S.J., Brown, N.M., Dougan, G., Brown, D, Riley, T., Kim, Hee Jung, Brazier, J, Kato, H, Connor, Thomas R, Fairley, D., Parkhill, J., Stephanie D'Arc, Wren, Brendan W., D'Arc, Stephanie, Douce, G., Lawley, TD, John E Coia, Fabio Miyajima, Michell, Stephen, Jon Brazier, Lawley, Trevor D., Martin, Melissa J., Miao He, Stephen Michell, Roberts, P., Koh, TH, Hawkey, Peter, Pickard, DJ, Bamford, Kathleen B, Douce, G.l, Roberts, P, Riley, T, Connor, TR, Senoh, M, Dougan, G   +154 more
core   +1 more source

The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. [PDF]

, 2011
BACKGROUND: Clostridium difficile is the major cause of antibiotic associated diarrhoea and in recent years its increased prevalence has been linked to the emergence of hypervirulent clones such as the PCR-ribotype 027. Characteristically, C.
McNerney Ruth, Cartman, Stephen T, Cartman Stephen T, Bundy, Jake, Richard H Barton, Bundy Jake, McNerney, Ruth, Elizabeth H Donahue, Ruth McNerney, Nigel P Minton, Wren, Brendan W, Donahue Elizabeth H, Jake Bundy, Donahue, Elizabeth H, Barton, Richard H, Barton Richard H, Dawson Lisa F, Lisa F Dawson, Stephen T Cartman, Wren Brendan W, Minton Nigel P, Dawson, Lisa F, Minton, Nigel P, Brendan W Wren   +23 more
core   +1 more source

Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo. [PDF]

PLoS ONE, 2016
Clostridium difficile is the principal cause of antibiotic-associated diarrhea. Major metabolic requirements for colonization and expansion of C. difficile after microbiota disturbance have not been fully determined. In this study, we show that glutamate
Brintha Parasumanna Girinathan, Sterling Braun, Apoorva Reddy Sirigireddy, Jose Espinola Lopez, Revathi Govind   +4 more
doaj   +1 more source

Development of a novel method for detection of C. difficile using HS-SPME-GC-MS [PDF]

, 2014
AIMS:A novel method has been developed that allows successful differentiation between Clostridium difficile culture-positive and culture-negative stool samples based on volatile organic compound (VOC) evolution and detection by headspace solid-phase ...
Dean, John, Stanforth, Stephen, Tait, Emma, Hill, Kerry, Perry, John   +4 more
core   +1 more source

Occurrence of Clostridium difficile in two types of wastewater treatment plants

Journal of the Formosan Medical Association, 2015
Wastewater is a potential environmental source of Clostridium difficile, although a direct link with community-acquired C. difficile infection (CA-CDI) in humans has not yet been established. The present study was performed to determine the occurrence of
Mahnaz Nikaeen, Hajar Aghili Dehnavi, Akbar Hssanzadeh, Mohammad Jalali   +3 more
doaj   +1 more source