C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency [PDF]
Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai +6 more
doaj +3 more sources
Secreted Phospholipases A2 in Hereditary Angioedema With C1-Inhibitor Deficiency [PDF]
Background Hereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling.
Stefania Loffredo +14 more
semanticscholar +6 more sources
Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity. [PDF]
Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Shamanaev A +9 more
europepmc +2 more sources
Clinical features of genetically characterized types of hereditary angioedema with normal C1 inhibitor: a systematic review of qualitative evidence [PDF]
Background Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH) (HAEnCI) is associated with skin swellings, abdominal attacks, and the risk of asphyxia due to upper airway obstruction. Several different gene mutations linked to the HAE phenotype
Konrad Bork +5 more
openalex +2 more sources
Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders.
Konrad Bork +2 more
doaj +2 more sources
Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor [PDF]
Acquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless ...
Meghan V. Matheny +2 more
doaj +2 more sources
C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury [PDF]
Background Preclinical studies indicate that the systemic application of C1-inhibitor, clinically used to treat hereditary angioedema, reduces secondary brain injury after ischemic stroke. This study assessed the effect of C1-inhibitor on secondary brain
Kevin Akeret +9 more
doaj +2 more sources
Editorial: C1 inhibitor deficiency and angioedema [PDF]
Henriette Farkas +2 more
doaj +2 more sources
A nationwide study of acquired C1-inhibitor deficiency in France
Acquired angioedema (AAE) due to C1-inhibitor (C1INH) deficiency is rare. Treatment options for acute attacks are variable and used off-label. Successful treatment of the associated lymphoma with rituximab seems to prevent acute attacks in subjects with ...
Delphine Gobert +13 more
openalex +2 more sources
C1 inhibitor deficiency enhances contact pathway-mediated activation of coagulation and venous thrombosis. [PDF]
Grover SP +16 more
europepmc +2 more sources

