C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency [PDF]
Orphanet Journal of Rare Diseases, 2023 Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai +6 more
doaj +5 more sources
Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity. [PDF]
Front Physiol, 2023 Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Shamanaev A +9 more
europepmc +2 more sources
Orphanet Journal of Rare Diseases, 2019 Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders.
Konrad Bork +2 more
doaj +2 more sources
Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency [PDF]
Frontiers in Immunology, 2018 BackgroundHereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that
Andrea Zanichelli +16 more
core +4 more sources
International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1-Inhibitor deficiency [PDF]
Allergy. European Journal of Allergy and Clinical Immunology, 2016 BACKGROUND: The consensus documents published to date on hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) have focused on adult patients. Many of the previous recommendations have not been adapted to pediatric patients.
Agostoni +122 more
core +4 more sources
Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor [PDF]
Case Reports in UrologyAcquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless ...
Meghan V. Matheny +2 more
doaj +2 more sources
C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury [PDF]
Fluids and Barriers of the CNSBackground Preclinical studies indicate that the systemic application of C1-inhibitor, clinically used to treat hereditary angioedema, reduces secondary brain injury after ischemic stroke. This study assessed the effect of C1-inhibitor on secondary brain
Kevin Akeret +9 more
doaj +2 more sources
Editorial: C1 inhibitor deficiency and angioedema [PDF]
Frontiers in Allergy, 2022 Henriette Farkas +2 more
doaj +2 more sources
Short-term Prophylaxis for Delivery in Pregnant Women with Hereditary Angioedema with Normal C1-Inhibitor [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2021 Objective To verify the efficacy of short-term prophylaxis for vaginal or cesarean section childbirth with plasma-derived C1-inhibitor concentrate in pregnant women. They should have hereditary angioedema (HAE) and normal plasma C1-inhibitor.
Caroline Guth de Freitas Batista de Moraes +5 more
doaj +2 more sources
International Archives of Allergy and Immunology, 2021 Introduction: Acquired angioedema with C1 inhibitor deficiency (AAE-C1-INH) is rare but a potentially life-threatening disease. There are no official prevalence data, nor approved therapies for this condition.
Marta Sobotková +8 more
semanticscholar +1 more source