Results 1 to 10 of about 117,459 (333)
C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency [PDF]
Orphanet Journal of Rare Diseases, 2023 Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai +6 more
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Editorial: C1 inhibitor deficiency and angioedema [PDF]
Frontiers in Allergy, 2022 Henriette Farkas +2 more
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Expression of platelet C1 inhibitor [PDF]
Blood, 1993 Abstract Human platelets contain a pool of C1 inhibitor (C1 INH) distinct from that in plasma. Twelve normal platelet samples washed by centrifugation had a mean platelet C1 INH antigen level of 19.3 +/- 2.8 ng (mean +/- SEM) per 10(8) platelets. These values contrast with the mean +/- SEM platelet C1 INH antigen level of 6.1 +/- 0.9 per
AH Schmaier +4 more
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Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate [PDF]
Orphanet Journal of Rare Diseases, 2019 Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders.
Konrad Bork +2 more
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The metabolism of C1 inhibitor and C1q in patients with acquired C1-inhibitor deficiency
Journal of Allergy and Clinical Immunology, 1986 The metabolism of 125I-labeled C1 inhibitor (C1INH) and C1q was studied in five patients with B cell lymphoproliferative disorders, C1INH deficiency, and angioedema. C1INH catabolism was markedly accelerated in these patients. The fractional catabolic rate (FCR) was 0.053 of the plasma pool per hour compared to that of normal subjects (0.025) or ...
J METARNED +3 more
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C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease [PDF]
Canadian Journal of Gastroenterology, 2000 A case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma.
Kelly W Burak, Gary R May
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Formation and properties of C1‐inhibitor polymers [PDF]
FEBS Letters, 1995 Heating of the serpin C1‐inhibitor above 55°C induced the formation of inactive polymers. Western blotting of non‐denaturing gels showed that the polymers bound to the conformation specific monoclonal antibody 4C3, suggesting that a similar conformational change to that occurring in complexed or cleaved inhibitor had taken place. N‐Terminal analysis of
P A Patston +3 more
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Structural and Functional Aspects of C1-Inhibitor
Immunobiology, 2002 C1-Inh is a serpin that inhibits serine proteases from the complement and the coagulation pathway. C1-Inh consists of a serpin domain and a unique N-terminal domain and is heavily glycosylated. Non-functional mutants of C1-Inh can give insight into the inhibitory mechanism of C1-Inh.
I BOS
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Short-term Prophylaxis for Delivery in Pregnant Women with Hereditary Angioedema with Normal C1-Inhibitor [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2021 Objective To verify the efficacy of short-term prophylaxis for vaginal or cesarean section childbirth with plasma-derived C1-inhibitor concentrate in pregnant women. They should have hereditary angioedema (HAE) and normal plasma C1-inhibitor.
Caroline Guth de Freitas Batista de Moraes +5 more
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Eurasian Journal of Emergency Medicine, 2022 Aim:We aimed first to investigate patients who received C1 inhibitor therapy in the emergency department (ED). The patients’ complaints, examination findings, length of stay in the ED and whether the patients were treated with anything other than C1 ...
Sercan Yalçınlı +2 more
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