Results 1 to 10 of about 3,092,507 (234)

C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai   +6 more
doaj   +5 more sources

Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity. [PDF]

open access: yesFront Physiol, 2023
Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Shamanaev A   +9 more
europepmc   +2 more sources

Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders.
Konrad Bork   +2 more
doaj   +2 more sources

Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency [PDF]

open access: yesFrontiers in Immunology, 2018
BackgroundHereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that
Andrea Zanichelli   +16 more
core   +4 more sources

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1-Inhibitor deficiency [PDF]

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2016
BACKGROUND: The consensus documents published to date on hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) have focused on adult patients. Many of the previous recommendations have not been adapted to pediatric patients.
Agostoni   +122 more
core   +4 more sources

Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor [PDF]

open access: yesCase Reports in Urology
Acquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless ...
Meghan V. Matheny   +2 more
doaj   +2 more sources

C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury [PDF]

open access: yesFluids and Barriers of the CNS
Background Preclinical studies indicate that the systemic application of C1-inhibitor, clinically used to treat hereditary angioedema, reduces secondary brain injury after ischemic stroke. This study assessed the effect of C1-inhibitor on secondary brain
Kevin Akeret   +9 more
doaj   +2 more sources

Editorial: C1 inhibitor deficiency and angioedema [PDF]

open access: yesFrontiers in Allergy, 2022
Henriette Farkas   +2 more
doaj   +2 more sources

Short-term Prophylaxis for Delivery in Pregnant Women with Hereditary Angioedema with Normal C1-Inhibitor [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2021
Objective To verify the efficacy of short-term prophylaxis for vaginal or cesarean section childbirth with plasma-derived C1-inhibitor concentrate in pregnant women. They should have hereditary angioedema (HAE) and normal plasma C1-inhibitor.
Caroline Guth de Freitas Batista de Moraes   +5 more
doaj   +2 more sources

Acquired Angioedema with C1 Inhibitor Deficiency: Occurrence, Clinical Features, and Management: A Nationwide Retrospective Study in the Czech Republic Patients

open access: yesInternational Archives of Allergy and Immunology, 2021
Introduction: Acquired angioedema with C1 inhibitor deficiency (AAE-C1-INH) is rare but a potentially life-threatening disease. There are no official prevalence data, nor approved therapies for this condition.
Marta Sobotková   +8 more
semanticscholar   +1 more source

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