Results 91 to 100 of about 117,459 (333)

Hereditary Angioedema due to C1-Inhibitor Deficiency in Pediatric Patients in Croatia – First National Study, Diagnostic and Prophylactic Challenges

Acta Clinica Croatica, 2019
Hereditary angioedema (HAE) is a rare autosomal dominant disease with deficiency (type I) or dysfunction (type II) of C1 inhibitor, caused by mutations in the C1-INH gene, characterized by recurrent submucosal or subcutaneous edemas including skin ...
Ljerka Karadža-Lapić, Marko Barešić, Renata Vrsalović, Irena Ivković-Jureković, Saša Sršen, Ingrid Prkačin, Matija Rijavec, Draško Cikojević   +7 more
doaj   +1 more source

Current and Future Therapy of Hereditary Angioedema

Southern Clinics of Istanbul Eurasia, 2020
Hereditary angioedema (HAE) is an autosomal dominant disorder, mostly due to C1 esterase inhibitor (C1-INH) deficiency, known by recurring angioedema attacks that are nonpruritic, not accompanying with urticaria, and involve the dermis, intestinal ...
Öner Özdemir
doaj   +1 more source

MASP-1 Induces a Unique Cytokine Pattern in Endothelial Cells: A Novel Link between Complement System and Neutrophil Granulocytes [PDF]

, 2014
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this immediate anti-microbial action.
A Krarup, A Mantovani, A Mocsai, A Mocsai, A Tedgui, A Ueda, Attila Mócsai, BK Rada, C Michiels, CI Oie, Csaba I. Tímár, D Heja, D Storm, DY Yuen, E Stylianou, EF Foxman, Erika Kajdácsi, G Ambrus, Ger van Zandbergen, I Kim, I Oynebraten, I Oynebraten, J Dobo, J Dobo, JM Park, JS Presanis, József Dobó, K Futosi, KM Valentijn, Krisztina Futosi, L Knipe, L Martorell, László Cervenak, M Megyeri, M Oroszlan, MG Rondaij, MP Delghandi, Márton Megyeri, N Szabo-Fresnais, NW Lukacs, Péter Gál, Péter K. Jani, QX Niu, R Dewberry, R Shreeniwas, RP Cherla, S Hippenstiel, S Thiel, SR Coughlin, V Bezzerri, V Mako, Veronika Makó, Zoltán Doleschall   +52 more
core   +2 more sources

Enhanced Switching Performance in Single‐Crystalline PbTiO3 Ferroelectric Memristors for Replicating Synaptic Plasticity

Advanced Functional Materials, EarlyView.
This study demonstrated single‐crystalline PbTiO3‐based memristors with atomically sharp interfaces, well‐ordered lattices, and minimal lattice mismatch. The devices exhibited an ON/OFF ratio exceeding 105, high stability, and rich resistance‐state modulation.
Haining Li, Zhiqiang Liao, Risa Kataoka, Md Sarker Shamim, Takeshi Kijima, Hiroyasu Yamahara, Hitoshi Tabata, Munetoshi Seki   +7 more
wiley   +1 more source

Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency: A Literature-Based Analysis and Clinical Commentary on Prophylaxis Treatment Strategies

World Allergy Organization Journal, 2011
Hereditary angioedema (HAE) caused by C1-esterase inhibitor deficiency is an autosomal-dominant disease resulting from a mutation in the C1-inhibitor gene.
Richard G Gower, MD, Paula J Busse, MD, Emel Aygören-Pürsün, MD, Amin J Barakat, MD, Teresa Caballero, MD, Mark Davis-Lorton, MD, Henriette Farkas, MD, David S Hurewitz, MD, Joshua S Jacobs, MD, Douglas T Johnston, MD, William Lumry, MD, Marcus Maurer, MD   +11 more
doaj   +1 more source

Magnetic‐Field Tuning of the Spin Dynamics in the Quasi‐2D Van der Waals Antiferromagnet CuCrP2S6

Advanced Functional Materials, EarlyView.
This study reveals 2D character of the spin dynamics in CuCrP2S6, as well as complex field dependence of collective excitations in the antiferromagnetically ordered state. Their remarkable tuning from the antiferromagnetic to the ferromagnetic type with magnetic field, together with the non‐degeneracy of the magnon gaps favorable for the induction of ...
Joyal John Abraham, Yaqian Guo, Yuliia Shemerliuk, Sebastian Selter, Saicharan Aswartham, Kranthi Kumar Bestha, Laura T. Corredor, Anja U. B. Wolter, Olga Kataeva, Luka Rogić, Noah Somun, Damjan Pelc, Oleg Janson, Jeroen van den Brink, Bernd Büchner, Vladislav Kataev, Alexey Alfonsov   +16 more
wiley   +1 more source

The effect of C1-esterase inhibitor on systemic inflammation in trauma patients with a femur fracture - The CAESAR study: study protocol for a randomized controlled trial

Trials, 2011
Background Systemic inflammation in response to a femur fracture and the additional fixation is associated with inflammatory complications, such as acute respiratory distress syndrome and multiple organ dysfunction syndrome.
Strengers Paul FW, Koenderman Anky HL, van Wessem Karlijn JP, Visser Tjaakje, Heeres Marjolein, Koenderman Leo, Leenen Luke PH   +6 more
doaj   +1 more source

Molecular Genetics of C1 Inhibitor

Immunobiology, 1998
More than 100 different C1 inhibitor gene mutations have been described in hereditary angioedema (HAE) patients. Sixty-nine mutations have been reported in patients with the quantitative C1 inhibitor defect (type 1 HAE) in two recent large-scale studies. These changes were found distributed over all exons and exon/intron boundaries.
openaire   +3 more sources

Tailored Reconstruction of Polycrystalline CuO Nanorods Promotes C─C Coupling in CO2 Electroreduction

Advanced Functional Materials, EarlyView.
Controlling the polycrystallinity of CuO nanorods enables directional reconstruction into rod‐like structures that stabilize Cu(OH)2 and increase Cu+ ratios, while modulating interfacial water dynamics to enhance C─C coupling and boost C2+ product formation in CO2 electroreduction.
Hyeon‐Seok Bang, Young‐Jin Ko, Hyo Sang Jeon, Eugene Huh, Eung Dab Kim, Min Gwan Ha, Chulwan Lim, Jiho Jeon, Seohyeon Ka, Dogyeong Kim, Xiaojie Zhang, Yeongjin Kim, Kyeongsu Kim, Woong Hee Lee, Jae‐Young Choi, Hyung‐Suk Oh   +15 more
wiley   +1 more source

The deficiency of C1 inhibitor and its treatment

Immunobiology, 2007
In this article, we review the traditional therapies of hereditary angioedema (HAE) that have been used for several years. Some of these therapies were proposed before the definition of the underlying defect and the understanding of the pathogenesis of the disease. We also describe new compounds under investigation at present as potential therapies for
M. Cicardi, L.C. Zingale
openaire   +3 more sources