Results 31 to 40 of about 3,095,271 (376)

WAO guideline for the management of hereditary angioedema [PDF]

, 2012
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel, Bork, Konrad, Bowen, Tom, Boysen, Henrik B., Craig, Timothy, Farkas, Henriette, Grumach, Anete, Katelaris, Constance H., Lockey, Richard, Longhurst, Hilary, Lumry, William, Magerl, Markus, Martinez-Saguer, Immaculada, Maurer, Marcus, Nast, Alexander, Pawankar, Ruby, Ritchie, Bruce, Zuraw, Bruce   +17 more
core   +1 more source

Successful C1 inhibitor short-term prophylaxis during redo mitral valve replacement in a patient with hereditary angioedema

Journal of Cardiothoracic Surgery, 2010
Hereditary angioedema is characterized by sudden episodes of nonpitting edema that cause discomfort and pain. Typically the extremities, genitalia, trunk, gastrointestinal tract, face, and larynx are affected by attacks of swelling.
Coleman Suzanne, Bernstein Jonathan A, Bonnin Arturo J   +2 more
doaj   +1 more source

Hereditary angioedema: approaches to diagnosis and treatment, analysis of a clinical family case

Медицинский совет, 2021
Hereditary angioedema belongs to the group of rare, orphan, genetically determined defects that represent a significant medical and social problem due to the pronounced impact on the quality of life and potential mortality, as well as the emerging ...
O. V. Skorohodkina, A. V. Luntsov, A. A. Vasileva, O. A. Bareycheva   +3 more
doaj   +1 more source

The hereditary angioedema burden of illness study in Europe (HAE-BOIS-Europe) : background and methodology [PDF]

, 2012
Background: Hereditary angioedema (HAE) is a rare but serious disease marked by swelling attacks in the extremities, face, trunk, airway, or abdominal areas that can be spontaneous or the result of trauma and other triggers.
Aygören-Pürsün, Emel, Beusterien, Kathleen, Boysen, Henrik B., Bygum, Anette, Caballero, Teresa, Gholizadeh, Shadi, Musingarimi, Patience, Wait, Suzanne   +7 more
core   +2 more sources

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain.

Blood, 2019
The plasma proteins factor XII (FXII) and prekallikrein (PK) undergo reciprocal activation to the proteases FXIIa and kallikrein by a process that is enhanced by surfaces (contact activation) and regulated by the serpin C1 inhibitor.
Ivan Ivanov, A. Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Dickeson, S. Kundu, I. Verhamme, A. Gruber, K. McCrae, D. Gailani   +10 more
semanticscholar   +1 more source

Lymphoproliferative disease and acquired C1 inhibitor deficiency

Haematologica, 2007
Angioedema due to acquired deficiency of the C1-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired C1 inhibitor deficiency: 23 have anti C1-inhibitor autoantibodies; 13 have monoclonal ...
Roberto Castelli, Daniela Lambertenghi Deliliers, Lorenza C. Zingale, Enrico Maria Pogliani, Marco Cicardi   +4 more
doaj   +1 more source

Risk of angioedema following invasive or surgical procedures in HAE type I and II : the natural history [PDF]

, 2013
Background: Hereditary angioedema (HAE), caused by deficiency in C1-inhibitor (C1-INH), leads to unpredictable edema of subcutaneous tissues with potentially fatal complications.
Aygören-Pürsün, Emel, Klingebiel, Thomas, Kreuz, Wolfhart, Martinez Saguer, Inmaculada, Schwabe, Dirk   +4 more
core   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H., Mitchell, Daniel A., Schmid, Ralf, Schwaeble, Wilhelm J., Wallis, Russell   +4 more
core   +1 more source

Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder [PDF]

, 2016
Background: Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are autoimmune demyelinating diseases distinguished clinically by selective involvement in NMOSD of optic nerves and spinal cord. Early clinical manifestations are
Evans, David R. S., Hakobyan, Svetlana, Harding, Katharine, Loveless, Samantha, Luppe, Sebastian, Morgan, Bryan Paul, Robertson, Neil P.   +6 more
core   +1 more source

Corrigendum: Breakthroughs in hereditary angioedema management: a systematic review of approved drugs and those under research

Drugs in Context, 2019
The authors wish to make corrections to their article: Nicola S, Rolla G, Brussino L. Breakthroughs in hereditary angioedema management: a systematic review of approved drugs and those under research. Drugs in Context 2019; 8: 212605. DOI: 10.7573/dic.
Stefania Nicola, Giovanni Rolla, Luisa Brussino   +2 more
doaj   +1 more source